Homeostasis Flashcards

0
Q

Endotherm

A

Animal that maintains a constant body temperature (mammal that does homeostasis)

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1
Q

Ectotherm (definition)

A

Animal which regulates it’s temperature by exchanging heat with its surroundings (doesn’t do homeostasis) e.g. Reptiles

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2
Q

Temperature control:

When an endotherm becomes too cold, what happens?

A
  • Thermoreceptors detect the fall in temperature
  • sends an impulse to hypothalamus in the brain
  • effector: arterioles muscles
  • response: vasoconstriction of arterioles near skin surface so blood is kept away from surface preventing heat loss
  • effector: hair erector muscles
  • response: hairs stand up and trap warm air close to skin
  • effector: skeletal muscles contract (shivering)
  • response: generates heat by respiration
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3
Q

Temperature control:

When an endotherm becomes too hot, what happens?

A
  • thermoreceptors detect rise in temperature
  • sends an impulse to hypothalamus in brain
  • effector: arterioles muscles
  • response: vasodilation of arterioles near skin so blood flows close to surface allowing heat loss by radiation through the skin
  • effector: sweat glands
  • response: secretion of sweat so skin loses heat (from blood) by evaporation
  • effector: salivary glands
  • response: panting allows heat (from blood) to be lost by evaporation
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4
Q

Heart rate control:

Why and how does the heart rate increase?

A
  • blood CO2 is high (due to respiration)
  • detected by chemoreceptors in the aorta
  • impulse sent to medulla oblongata
  • impulse sent back to heart muscle
  • SAN causes heart rate to speed up (via sympathetic nerves)

SOMETIMES: (in extreme situations)
-adrenal gland is stimulated to secrete adrenaline to speed up heart rate

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5
Q

Heart rate control:

Why and how does the heart rate slow down?

A
  • blood CO2 is low
  • detected by chemoreceptors in aorta
  • impulse sent to medulla oblongata
  • impulse sent back to heart muscle
  • SAN causes heart rate to slow down (via parasympathetic nerves)
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6
Q

Which nervous system speeds things up?

A

Sympathetic nervous system

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7
Q

Which nervous system slows things down?

A

Parasympathetic nervous system

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8
Q

What does the sympathetic nervous system do?

A

Speed things up

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9
Q

What does the parasympathetic nervous system do?

A

Slows things down

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10
Q

What do endocrine glands do?

A

Secrete hormones into the blood

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11
Q

What kind of glands secrete hormones?

A

Endocrine glands

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12
Q

Hormone definition

A

A protein that is secreted into the blood, binds to target cells with the complementary receptor.
Can have a widespread (long term) effect and spread by diffusion

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13
Q

What do exocrine glands do?

A

Secrete a product via a duct onto the surface next to the gland (e.g. Saliva, sweat)
Stimulated by hormone secretion
E.g. Pancreatic secretions in small intestine

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14
Q

Is the pancreas an endocrine gland or an exocrine gland?

A

Both

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15
Q

Why is the pancreas an endocrine gland?

A

It secrete hormones

Insulin and glucagon to control blood glucose

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16
Q

Why is the pancreas an exocrine gland?

A
  • enzymes are secreted (e.g. Amylase, trypsin)
  • secretions are controlled by nerves and hormones
  • pancreatic secretions go into small intestine
  • pancreatic secretions make small intestine alkaline
17
Q

Which two hormones regulate blood glucose?

A

Insulin and glucagon

18
Q

Where are the alpha and beta cells?

A

In the islets of Langerhans in the endocrine tissue of the pancreas

19
Q

When and where from is insulin secreted?

A
  • secreted from Beta cells

- when blood glucose is too high

20
Q

What happens when blood glucose is too high?

A
  • high blood glucose is detected by beta cells
  • insulin is secreted into the blood from beta cells in islets of Langerhans in pancreas
  • insulin binds to receptors on liver cells
  • activating carrier proteins, increasing membrane permeability to glucose
  • allows glucose to be taken into cells
  • activates enzymes involved in glycogenesis which converts glucose into glycogen
21
Q

What happens when blood glucose is too low?

A
  • low blood glucose is detected by alpha cells
  • glucagon is secreted into the blood from alpha cells in the islets of Langerhans in the pancreas
  • glucagon binds to receptors on liver cells
  • activates enzymes used in glycogenolysis (converting glycogen to glucose)
  • glucose diffuses into blood
22
Q

What is Gluconeogenesis?

A

Making glucose from glycerol and fats when glucose is very low (in extreme situations)

23
Q

How does adrenaline increase blood glucose concentration?

A

-adrenaline binds to a receptor on the cell membrane
(Adrenaline is too big to pass through cell membrane by diffusion)
(Adrenaline must use channel protein to pass into cell)

-inside cell, ATP is converted to cAMP
-cAMP activates the protein channel
-protein channel changes shape so adrenaline can pass through
-enzymes in the cell are activated
-glycogenolysis and Gluconeogenesis occur to make glucose
(Glycogenesis is inhibited)

24
what is cAMP
- a secondary messenger | - ATP with 2 phosphate groups removed
25
When does type 1 diabetes occur?
When there is a lack of insulin because the immune system destroys most/all beta cells in pancreas Tends to be present from birth (genetic)
26
How is type 1 diabetes managed?
Regular injections of insulin
27
When does Type 2 Diabetes occur
When the body does not produce enough insulin/ insulin produced doesn't affect target cells Usually doesn't develop until 40s+
28
How can type 2 diabetes be managed?
Can be controlled by diet (e.g more complex carbohydrates and less simple carbohydrates) and exercise But sometimes insulin injections are required
29
How can type 2 diabetes be caused?
- increasing age - genetics - obesity - high sugar intake - lack of exercise - high blood pressure - excessive alcohol intake - more common in some ethnic groups - more common in males
30
How can insulin be made for diabetics?
- pig insulin (taken from pigs) | - bacteria produced human insulin
31
Why might people disagree with the use of pig insulin?
- religious, ethical reasons - health scares (e.g. Swine flu) - some people react to it as it is pig insulin
32
Why might bacteria produced insulin be better than the use of pig insulin?
- pigs are expensive to look after - pig insulin may be ineffective in some people - bacteria produced insulin is cheaper to produce - less space is required for producing insulin with bacteria - bacteria produce human insulin, so there will be no reactions against it and a better tolerance
33
What is the Oestrous cycle?
Changes in hormone concentrations in mammalian fertility
34
How is the oestrous cycle controlled?
Controlled by negative and positive feedback loops
35
What does oestrogen do?
- prepares the follicle in the ovary for the release of an egg - thickens uterus lining - causes positive feedback as FSH and LH are produced
36
What does FSH do?
- stimulated development of follicles in the ovary to ripen eggs - causes positive feedback and LH is then produced
37
What does LH do?
- further triggers ovulation a (release of an egg) | - causes positive feedback as progesterone is then produced
38
Where is progesterone secreted from?
The corpus luteum (after realise of an egg)
39
What does progesterone do?
- maintains the uterus lining (thickening) ready for implantation of an egg - causes negative feedback as it stops production of all other hormones
40
If egg is fertilised, what happens to level of progesterone?
Stays HIGH
41
If egg is not fertilised, what happens to hormone levels?
Progesterone level decreases, allowing cycle to begin again