Homeostasis Flashcards
1
Q
What is homeostasis?
A
- Motivation to maintain optimal conditions for your body e.g., water, sodium, temperature etc.
- Many homeostatic systems are a combination of physiology and behaviour i.e., balance of water and sodium includes a behavioural component of drinking water (thirst).
2
Q
What is the basic concept of homeostasis?
A
- A homeostatic system requires a set point, a detection mechanism, and mobilisation of behaviour when deviation occurs.
3
Q
What is fluid balance?
A
- Very little surplus water is stored in the body.
- We coordinate physiology and behaviour to maintain body water concentration at a predetermined set point.
- 67% of water is located inside cells, 7% is blood plasma, and 26% is interstitial fluid (between cells fluid).
4
Q
What is osmotic thirst?
A
- The motivation to seek and ingest water (Fitzsimons., 1988).
- The body’s extracellular fluid contains 8.5g of sodium chloride per litre.
- Ingestion of salt increases the concentration of sodium chloride in the extracellular fluid, which creates osmotic pressure and forces fluid out of the cell.
- Osmotic thirst = remedied by drinking water
5
Q
What is Endocrine Regulation of Osmotic Thirst?
A
- Osmoreceptor cells in the hypothalamus detect an increase in osmolarity.
- Antidiuretic hormone (ADH; also called vasopressin) is made by the hypothalamus, and then transported down the nerve fibres to the posterior pituitary gland where it is released into the bloodstream.
- ADH acts to conserve water as blood moves through the kidneys, increasing permeability of renal tubules, and releasing more fluid back into circulation.
6
Q
What is Hypovolemic Thirst?
A
- Fluids can also be lost by blood loss, vomiting, or diarrhoea without depleting the intracellular fluid -> water solutes are lost.
7
Q
What is Endocrine Regulation of Hypovolemic Thirst?
A
- Loss of blood volume causes low blood pressure and prevents the kidneys from extracting water efficiently.
- When loss of blood volume is detected, ADH restricts the blood vessels, increasing blood pressure (Gauer & Henry., 1963).
8
Q
Behavioural regulation of hypovolemic thirst:
A
- Water is consumed > body fluids are diluted > reduced blood plasma osmolality > stimulus to stop drinking.
- Hypovolemic thirst is best remedied by the replacement of water