Homeostasis Flashcards
Blood glucose concentration regulation
-Pancreas detects and islets of Langerhans release insulin from the b cells and glucagon from the a cells
-Adrenaline causes more glucose to be released from the hydrolysis of glycogen in the liver
How does insulin lower blood glucose
-Liver cells become more permeable to glucose
-Enzymes are activated to cause glycogenesis
-Glucose to glycogen
Attaches to receptors to change tertiary structure of channel proteins so more facilitated diffusion , vesicles containing glut 4 glucose channel protein fuse with cell surface membrane
How does glucagon increase blood glucose
-Activates enzymes to hydrolyse glycogen
-Glycogen hydrolysed to glucose
Attaches to receptor to change shape into adenylate cyclase and converts ARP into cyclic ATP which activates Kinase protein to hydrolyse glycogen and also activates enzymes in gluconeogenesis
How does adrenaline increase blood glucose
-Causes G protein to be activated and convert ATP into CAMP