Homeostasis Flashcards
What is homoeostasis?
It means keeping things constant.
Comes from two Ancient Greekwords:
‘homeo,’meaning’similar,‘
‘stasis,’ meaning’stable.’
Homeostasis definition:
The condition of a relatively stable internal environment, maintained within narrow limits. When deviations (increases or decreases) occur in the internal environment of a healthy organism, mechanisms act to restore values to the normal (optimum) state.
What internal conditions need to be controlled?
Carbon dioxide, oxygen, wastes, temperature, salts, water, pH & glucose
What does SR MERF (Steady State Control Systems) stand for?
Stimulus- change in internal environment
Receptor- detects the change
Modulator- control centre (processes info from receptors, compares info to optimum, sends message to effector)
Effector- carries out the response (muscle or gland)
Response- counteracts the stimulus
Feedback- original stimulus changed
What is a negative feedback loop?
An increase in one thing leads to a decrease in another. Eg increased insulin production leads to decreased glucose in the blood
What is a positive feedback loop?
An increase in one thing leads to an increase in another. Eg increased eostrogen secretion leads to increased LH secretion
What does the human body do when it gets cold to decrease heat loss?
Constriction of blood vessels in the skin, reduction in sweating, conscious behaviour such as putting on a jumper or sheltering from the wind and reduction of surface area such as by curling into a ball.
What does the human body do when it gets cold to increase heat production?
Shivering, increase in voluntary activity and increased metabolic rate (long term response).
What does the human body do when it gets too hot to increase heat loss?
Dilation of blood vessels in the skin, sweating, conscious behaviour such as removing clothing or turning on a fan and increase surface area by spreading out.
What does the human body do when it gets too hot to decrease heat production?
Decrease in voluntary activity and decreased metabolic rate (long term response).
SR MERF for when the human body gets hot:
S- ↑Temp of blood
R- Thermoreceptors in hypothalamus
M- Hypothalamus
E - sweat glands, blood vessels, Skeletal muscle, Thyroid
R - ↑ sweat production, vasodilation, seek shade/ ↑ surface area, ↓ thyroxine ↓MR
F- ↓temp of blood
An increase in body temperature brings about a range of responses that serve to decrease the body temperature (negative feedback)
SR MERF for when the human body gets cold:
S- ↓Temp of blood
R- Thermoreceptors in hypothalamus
M- Hypothalamus
E - Blood vessels, Skeletal muscle, Thyroid
R - vasoconstriction, shivering/↓ surface area/seek warmth, ↑Thyroxine ↑MR
F- ↑temp of blood
A decrease in body temperature brings about a range of responses that serve to increase the body temperature (negative feedback)
Why do body levels need to be maintained within limits?
- Carbon dioxide - when dissolved in water forms carbonic acid, lowering pH and affecting enzyme activity
- Oxygen - to supply energy (ATP) for cellular functioning
- Nitrogenous Wastes - toxic - high concentrations inhibit the reactions that form them, also raises pH
- Temp - affects enzyme activity (metabolism)
- Salts - Na+ from NaCl important in regulating fluid levels as well as nerve transmission and muscle contraction
- Water - maintains conc. of cell contents at correct level for cellular reactions. Solvent for metabolic reactions
Heat lost through radiation:
- No physical contact
- Waves of energy
- The sun
- 65% of body heat lost this way
Heat lost through conduction:
- Contact
- Passes from one molecule to another
- 2% of body heat lost this way in air
Heat lost through convection:
- Cool air that comes into contact with a warm body is heated, expands, becomes less dense, so rises
- Approx 15% of body heat lost this way (in air)
Heat lost through evaporation:
- To break their cohesive bonds (evaporate) water molecules must be 100oC
- Takes a relatively large amount of heat with it
- Water has a cooling power approx. 50x greater than air
- Approx 20% of body heat lost this way
85% of heat is lost this way during intense activity
What is an ectotherm?
- Gain heat from external environment (sun/warm rocks/water)
- Body temp fluctuates
- May regulate temp through behaviour
- Most invertebrates, reptiles, amphibians and fish
Advantages of an ectotherm:
- Little energy required (low MR)
- Can feed less often
- Stay in shelter longer
Disadvantages of an ectotherm:
- Inactive in cold, night
- More likely to get eaten
- Restricted geographic range
What is an endotherm?
- Body heat from metabolic activity (internal)
- High metabolism
- Relatively constant temp
- Birds, mammals, some fast fish (tuna), some insects (bumble bees)
Advantages of an endotherm:
- Body temp constant
- Active at any temp (24hrs/day, any geographic region)
- Able to avoid predators
- Makes them good predators
Disadvantages of an endotherm:
- Large energy requirement (high MR)
- Need insulation and/or cooling mechanisms
Ectotherm vs endotherm body temperature:
- Generally an endotherm’s body temperature remains relatively stable despite the environmental temperature whereas as ectotherms temperature varies with that of the environment
- Endotherms require less energy to maintain their body temperature as the temperature of their surroundings increases.
- Oxygen consumption is a measure of aerobic respiration (metabolism)