Hodgkin & Non-hodgkin lymphoma Flashcards
1
Q
Describe the basic anatomy of a normal lymph node and the common abnormal lymph node patterns seen in lymphomas.
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2
Q
- Define lymphadenopathy and list the common disease categories associated with lymphadenopathy.
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3
Q
- Explain the basic principles for the WHO Classification of lymphomas. (Do not need to memorize the entire classification system.)
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morphology, immunophenotype, genetic findings, location, and age.
4
Q
- Define common non-Hodgkin lymphomas based on the cytology, pattern of growth, immunophenotype and genetic alteration.
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5
Q
- Define indolent, aggressive and highly aggressive as these terms relate to lymphoma. Be familiar with some common types of indolent and aggressive lymphomas.
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6
Q
- List and describe the common types of lymphoma in adults and children.
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7
Q
- Explain the importance of rearrangements involving the BCL2, BCL1 and MYC genes in the pathogenesis of lymphoma.
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8
Q
- List and describe the major subtypes of classical Hodgkin lymphoma (CHL).
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9
Q
- Describe and recognize the Reed-Sternberg (RS) cell in CHL.
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10
Q
- Describe the classification systemfor plasma cell neoplasms and explain the major differences among different subtypes.
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11
Q
- Identify the common location of plasma cell myeloma and plasmacytoma, and describe the morphologic features of the tumor cells.
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12
Q
- Describe typical radiographic and clinical laboratory findings in a patient presenting with plasma cell myeloma.
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13
Q
- Define MGUS, smoldering myeloma and indolent myeloma.
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