HNS01 Overview of the CNS

Question 1

Name three receptors that are responsible for homeostatic coordination of brain processes. Classify them as metabotropic / ionotropic.

Answer 1

1. Metabotropic
   - Metabotropic glutamate R
   - GABA_B R
2. Ionotropic
   - AMPAR
   - NMDAR
   - GABA_A R

Question 2

Name three receptors involved in depression. Classify them as metabotropic / ionotropic.

Answer 2

1. Metabotropic
   - Serotonin R (5-HT_3 R)
   - Norepinephrine R
2. Ionotropic
   - Serotonin R (5-HT_1,2,7 R)

Question 3

Name a receptor involved in Parkinson’s disease and addiction. Classify it as metabotropic / ionotropic.

Answer 3

Dopamine R (metabotropic)

Question 4

Classify acetylcholine receptors into metabotropic / ionotropic.

Answer 4

Muscarinic -> metabotropic
Nicotinic -> ionotropic