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Human Neuropsychology Exam 2 > HNP Midterm2 > Flashcards

HNP Midterm2 Flashcards

1
Q

What is the largest region of the brain

A

Frontal lobes

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2
Q

Where is the location of the frontal lobes

A

everything anterior to the central sulcus

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3
Q

Name the three major divisions of the frontal lobes

A

Primary Motor Cortex
Premotor Cortex
Prefrontal Cortex

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4
Q

Primary motor cortex is for what type of movement?

A
  • elementary movement such as mouth, limbs, movement force and direction
  • This is the actual mechanism for the execution of movement
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5
Q

Premotor cortex is responsible for ?

A

Selects the movements to be executed by the motor cortex

- selects coordinated movement sequences

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6
Q

Prefrontal cortex is responsible for ?

A

cognitive processes that select appropriate movements at the correct time and place

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7
Q

3 subdivisions of prefrontal cortex

A

Orbitofrontal cortex
Dorsolateral Prefrontal Cortex
Ventromedial Prefrontal Cortex

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8
Q

What is the main input from in the orbitofrontal cortex

A

Temporal Lobes

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9
Q

Dorsolateral Prefrontal Cortex has key functions tied to?

A

Posterior parietal Cortex

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10
Q

Ventromedial Prefrontal Cortex connects subcortically with the

A

Amygdala
Hypothalamus
and can influence emotional behaviour body wide

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11
Q

What cortex is important for External Cues?

A

Orbitofrontal cortex

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12
Q

What are external Cues?

A

We get feedback about our behaviour from the environmental stimuli. Feedback cues are central to a lot of our decision-making processes.

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13
Q

What cortex is important for internal cues?

A

Dorsolateral Prefrontal Cortex

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14
Q

People with damage to their temporal memory become dependent on _____ ____ to determine their behaviour

A

environmental cues

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15
Q

People with damage to their temporal memory have difficulty suppressing movements directed at ?

A

external cues

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16
Q

External cues are also used for ?

A

Language

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17
Q

Internal Cues are a function of what cortex?

A

Dorsolateral Prefrontal Cortex

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17
Q

Internal Cues are a function of what cortex?

A

Dorsolateral Prefrontal Cortex

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18
Q

What is temporal memory or Short-Term Memory ?

A

record of recent neural events and the order in which they occur.

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19
Q

Internal Cues come from?

A

dorsal or ventral streams

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20
Q

Context Cues are a function of what cortex?

A

Orbitofrontal Cortex

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21
Q

Damage to the orbitofrontal cortex have difficulty with?

A

interpreting context and altering behaviour appropriately.

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22
Q

what is Autonoetic Awareness ?

A

Autobiographical memory, awareness of oneself or self-knowledge. Our behaviours are influenced by a lifetime of experiences

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23
Q

If you have no autobiographical memory you would have difficulty with?

A

Deficits in self-regulation

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24
Q

Patients with damage to the medial or ventral frontal-lobe injuries lose ?

A

Autonoetic Awareness

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25
Q

Left frontal lobe are important for?

A

setting tasks, language related movements (speech), and Short term memory for verbal cues

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26
Q

Right frontal lobe is in charge of?

A

monitors ongoing tasks, non-verbal movements (facial expressions), Short term memory for non-verbal cues

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27
Q

both frontal lobes play a key role in ?

A

nearly ALL behaviours (so you don’t get the same lateralization as seen in the posterior regions of the brain).

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28
Q

The interpretation of context can also relate to affect, arises from connections to the _______

A

Amygdala

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29
Q

patients who have damage to prefrontal cortex have intact ______ skills such as memory or language but they could not regulate their _____ in appropriate ways

A
  1. Cognitive

2. Behaviours

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30
Q

Symptoms of frontal-lobe lesions can be roughly grouped into five separate categories what are they?

A
  • Motor disturbances
  • Loss of divergent thinking
  • Environmental control of behaviour
  • Poor temporal memory
  • Other
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31
Q

What are the 4 key studies looking at temporal memory

A
  1. Passingham-
  2. Funahashi
  3. Mishkin & Manning
  4. Petrides
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31
Q

Examples of Loss of divergent thinking there are 3?

A
  1. Reduced spontaneity
  2. Poor strategy formation
  3. Poor frequency estimate
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32
Q

Examples of motor disturbances

A 
1 Loss of fine movements
2 Loss of strength
3 Poor movement programming
4 Poor voluntary eye gaze
5 Poor corollary discharge
6 Broca’s aphasia
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32
Q

Examples of Environmental control of behaviour

A
  1. Poor response inhibition
  2. Impaired associative learning
  3. Risk taking and rule breaking
  4. Gambling
  5. Self-regulatory disorder
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33
Q

Examples of Poor Temporal Memory

A
  1. Poor working memory

2. Poor delayed response

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34
Q

Examples of Other Symptoms ?

A
  1. Impaired social behavior
  2. Altered sexual behavior
  3. Impaired olfactory discrimination
  4. Disorders associated with damage to the facial area
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35
Q

What were the findings of the Passingham study?

A

Animals with DLPFC lesions were terrible and constantly opened the same door

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36
Q

What are the findings of the Funahashi study?

A

Damage to DLPFC, impaired ability to remember the location of the target in the contralateral visual field

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37
Q

What are the findings of the Mishkin & Manning study?

A

damage to MPFC impairs this task

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38
Q

What are the findings of the Petrides study?

A

DLPFC must play a role in monitoring self-generated response

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39
Q

What is Psuedodepression symptoms? What side is the damage on?

A

outward apathy and indifference, loss of initiative, reduced sexual interest, litter overt emotion, little or no verbal output

DAMAGE TO LEFT HEMISPHERE

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40
Q

What are Pseudopsychopathic symptoms? What side is the damage on?

A

immature behaviour, lack of tact of restraint, coarse language, promiscuous sexual behaviour, increased motor activity, and general lack of social graces.

DAMAGE TO RIGHT HEMISPHERE

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41
Q

Does laterality exist?

A 
Yes, laterality exist
OFC damage (LEFT) introduces abnormal sexual behaviours like public masturbation. DLPFC damage (RIGHT) appears to reduce interest in sexual behaviour
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42
Q

damage to the ______ results in more dramatic personality changes than damage to the _____

A
  1. orbitofrontal cortex

2. DLPFC

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43
Q

Context cues provide context to?

A

Context cues provide context to our memories and helps to explain social behaviours.

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44
Q

Right Temporal cortex damage does what to memories?

A

impaired facial recognition, spatial position, maze learning, nonverbal, trouble with corsi block-tapping test

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45
Q

Left Temporal cortex damage does what to memories?

A
  • impairs memory for word lists, lists of consonants, and nonspatial associations, verbal, hebb digits test trouble
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46
Q

Language processing has a dorsal and ventral pathway. What do the Dorsal Pathways convey?

A

Dorsal pathway conveys phonological info for articulation

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47
Q

Language processing has dorsal and ventral pathway. What does the Ventral Pathways convey?

A

The ventral pathway provides semantic info for meaning

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48
Q

What are the three classifications of aphasic syndromes

A

Fluent Aphasia, Nonfluent Aphasia, and Pure Aphasia

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49
Q

What are the four behavioural components of emotion?

A

1) Psychophysiology
2) Distinctive Motor Behaviour
3) Self-reported cognition
4) Unconscious behaviour

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50
Q

Name the four social brain networks

A

Amygdala network
Mentalizing network
Empathy network
Mirror/stimulation/action–perception network

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51
Q

Amygdala network Function does what?

A
  • triggering emotional responses

- detecting socially relevant stimuli

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52
Q

Mentalizing network function?

A

it provides a mechanism for understanding others’ actions

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53
Q

Empathy network function?

A

The empathy network can attribute intentions to others, something we humans do automatically.

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54
Q

Mirror/stimulation/action–perception network function ?

A

thought to be involved in developing our concept of self

55
Q

What causes Kluver-Bucy syndrome?

A

It is caused by removing the amygdala

inferior temporal lobe bilaterally

56
Q

Key features of Kluver-Bucy syndrome

A

lack of affect, those with KB show no fear whatsoever of threatening stimuli.

57
Q

Why were frontal lobotomies done?

A

Because removal of the frontal lobe in ONE single chimpanzee made the animal more relaxed
- thought it would cure depression

58
Q

What were the behaviours following frontal lobotomies

A

severe effects on social and affective behaviour across the board.

62
Q

What are some of the common standard neuropsychological tests of frontal lobe functioning? There are 6

A 
Thurstone word fluency test
Finger tapping
Token test
Tower of London
BRIEF 
Self-ordering
63
Q

Adolescents who score higher on IQ tests produce more _____ and _______ in childhood?

A

Produce more synapses in childhood and prune more of them

64
Q

Do frontal lobe injuries interfere with divergent or convergent thinking more?

A

Divergent thinking

65
Q

What evidence suggests that the prefrontal cortex is related to human intelligence?

A

The size of the prefrontal cortex has expanded rapidly in human evolution which suggest this region is related to human intelligence

66
Q

What is Crystallized Intelligence?

A

The ability to apply previous learning

67
Q

What is Convergent Thinking?

A

When there is one correct answer

68
Q

What is Fluid Intelligence?

A

Involves seeing relationships and drawing logical conclusions

69
Q

What is Divergent Thinking?

A

Open ended questions that do not have one single correct answer

70
Q

What type of intelligence and thinking is tested with a standard IQ test?

A

Crystallized intelligence and convergent thinking

71
Q

What areas of the brain is related to IQ?

A

posterior parietal cortex
prefrontal cortex
the amount of gray matter

72
Q

What are the three major categories of memory?

A
  1. Explicit (Conscious) Memory
  2. Implicit (unconscious) Memory
  3. Emotional Memory
73
Q

What is Explicit Memory and it’s subdivisions?

A

Memory for events and facts that can be spontaneously recalled

  1. Episodic = autobiographical
  2. Semantic = Factual and general knowledge
74
Q

What is Implicit Memory?

A

Unconscious

Memory for skills, conditioned responses and those that require priming.

75
Q

What is Emotional Memory?

A

Conscious and non-conscious

Memory for recalling affective properties of stimuli or events

76
Q

Which types of memory was H.M. impaired on?

A

H.M. was impaired in both his episodic, semantic (retained some) and emotional memory (his amygdala was removed)

77
Q

What is Hemispheric Encoding and Retrieval Asymmetry (HERA)?

A

“An interesting pattern of hemispheric asymmetry emerges in comparisons between memory encoding and retrieval.”

These are active cortical areas that are revealed with PET scans during the acquisition or recall of VERBAL information.

78
Q

Which hemisphere is responsible for retrieval?

A

The RPFC

The retrieval of episodic memories (spatial)

79
Q

Which hemisphere is responsible for encoding?

A

LPFC

Encoding semantic and episodic memory (language)

80
Q

Why would there be hemispheric differences in encoding and retrieval?

A

Because information storage may require language but the retrieval of information may use spatial processing

81
Q

What are the 3 Theories of Memory?

A
  1. Consolidation Theory
  2. Multiple-Trace Theory
  3. Reconsolidation Theory
82
Q

What is the Consolidation Theory of Memory?

A

A process where the HPC dependant memories become independent of the HPC. Memories are held in the HPC until they can be moved to the cortex.

83
Q

What is the Multiple-Trace Theory of Memory?

A

This theory hypothesized that in any learning event, memories are encoded separately in different brain regions,

84
Q

What is the Reconsolidation Theory of Memory?

A

This theory states that memories will rarely consist of a single trace or neural substrate, suggesting that every time you recall a memory and do something with it, the memory is restored and reconsolidated and stored as a new memory.

85
Q

What are the major components of sound/ Components of sound-based language? (7 of them)

A
  1. Phonemes - fundamental sounds
  2. Morphemes - smallest meaningful units of a word. (Ex: “ing” or “s”)
  3. Lexicon- word memory (dictionary)
  4. Syntax- Grammar/ word order
  5. Semantics- word meaning
  6. Prosody- innotation, often reflects the emotional state of the speaker and can modify the literal meaning of the words and sentences (Ex: Sarcasm)
  7. Discourse- highest level of language processing, creating meaningful narratives
86
Q

What Is the relationship between age of language acquisition and injury?

A

When two languages are learned in childhood they share the same parts of the brain, but when a second language is learned in adulthood it is anatomically separated from the first.
Ex: patient K.H.

87
Q

What were the major findings in the video we watched on babies and language acquisition?

A

The benefits of human interaction in language acquisition

Ex: A baby can not learning Spanish from only watching Dora

88
Q

What is the Achievement Gap?

A

The achievement gap describes between group differences in educational outcomes . (SES)

89
Q

What is the Achievement Gap in learning new words in early life? Why?

A

The number of spoked words by professional families is roughly 1100 at 36 months compared to 500 in children from welfare families.
May be due to the number of words spoken to the child

90
Q

What are the two major theories of langauge?

A

Continuity Theory

Discontinuity Theory

91
Q

What is the Continuity Theory of language and what evidence is used to support it?

A

This theory argues that language evoked gradually. Similarities in genes and behaviours from ancestral species were modified in modern humans and produced language

92
Q

What is the Discontinuity Theory of language and what evidence is used to support it?

A

Discontinuity theories emphasize the syntax of human languages and proposes that language arose quite suddenly in modern humans
- human larynx

93
Q

We watched a video about still face and early life comprehension, what was the finding?

A

Children have great emotional processing

94
Q

What were the results of the William And Bargh 2008 study?

A

People who drink hot beverages are perceived by others are more caring
People who drink colder drinks are perceived as more negative

95
Q

What are the neural correlates of an emotional response?

A 
the cortex
thalamus
HPC, 
hippocampal formation 
amygdala
96
Q

What is the PFC responsible for in emotion?

A

Specifically the OFC and VMPFC and amygdala hold the key to understanding the nature of the emotional experience

97
Q

What is the OFC responsible for in emotion?

A

Represents positive and negative rewards and learns which previously neutral stimuli are associated with positive and negative rewards and when these associations change

98
Q

What is the Amygdala responsible for in emotion?

A

Emotional processing especially for fear, then sends stress response which releases stress hormones, then autonomic NS to suppress pain and stimulate arousal and attention with fearful stimuli

99
Q

What is the Hippocampus responsible for in emotion?

A

provides context to memories and spatial memory

100
Q

What are the results of the Downer Experiment

A

Depending on which side of the amygdala they removed, it would change how they view the stimulus. Whether they are scared or it or they are not.
- Patients showed intense fear from the intact side

101
Q

What role does dopamine play in adolescence?

A

There appears to be a shift in dopamine production and utilization. Seen in the PFC
- These levels can be altered by drug use and lead to additions

102
Q

What is ‘Reward Deficiency Syndrome’

A

Low levels of dopamine in limbic system characterized by
experimentation with addictive drugs
novelty seeking

103
Q

What Are the 3 major attention networks?

A

Alerting network
Orienting Or Engage/ Disengage Network
Executive Network

103
Q

What are the ventral spatial behaviour networks?

A

Ventral Stream- projects through the temporal lobes to FL to mediate perception

104
Q

How can we model spatial behaviour in rodents?

A

Morris water maze

105
Q

How was Homer able to locate his car in the video we watched?

A

Place cells: active when entering a specific location in the environment
Head-direction Cells: discharge whenever a rat points its head in a particular direction and different populations of cells have different preferred directions
Grid Cells: fire a regularly used nodes used to divide the environment into a grid and cells divide the environment into equilateral triangles

106
Q

What is the dorsal attention stream?

A

Dorsal –right lateralized and key to neglect - Top-down synchronization of visuospatial information

107
Q

How can we model spatial behaviour in rodents?

A

Morris water maze

108
Q

What is the ventral attention stream?

A

Ventral – Pulvinar nuclei, winner takes all, like the monkeys with the rewarding vs non rewarding stimuli. Is a bottom-up process for disengaging.

109
Q

What is the neurological evidence for attention? There are 4

A

Divided attention
selective attention
parallel processing
cross modal parallel

110
Q

What is divided attention?

A

Our perceptual system does not always work at peak efficiency: we have limited capacity and mush share attentional processes

111
Q

What is selective attention

A

more attention = more neural energy needed

112
Q

What are the major impairments of spatial ability? There are 6

A
  • Topographic disorientation
  • Egocentric Disorientation (uni or bilaterally)
  • Heading Disorientation (right)
  • Landmark Agnosia (bilaterally or right)
  • Anterograde Disorientation (Right)
  • Spatial distortion
113
Q

What is parallel processing?

A

our ability to deal with multiple stimuli simultaneously

114
Q

What is Cross Modal processing?

A

We receive a lot of stimuli and we must allocate our attention to both within and between modalities

114
Q

What are the two types of attention processing?

A

Automatic Process

Attentive Processing

115
Q

What is automatic attention processing? Bottom up or Top Down?

A

Involuntary, those that are performed without intention and without producing interference with ongoing activities, may be an innate property of sensory processing. Bottom-up (prompted by external stimuli)

116
Q

Is automatic attention processing Bottom-Up or Top-Down?

A

Bottom- up

117
Q

Is attentive attention processing Bottom-Up or Top-Down?

A

Top-Down

118
Q

What attention network is disturbed by Aging, ADHD

A

The alerting network

119
Q

What attention network is disturbed by Autism, PTSD, Neglect

A

Orienting network

120
Q

What attention network is disturbed by Anxiety, Depression, OCD

A

Executive network

121
Q

The ventral visual stream role in consciousness?

A

is important for recognizing objects, is part of consciousness,

122
Q

The dorsal visual stream role in consciousness?

A

The dorsal visual stream, which guides movement, is NOT part of consciousness.

123
Q

What evolutionary advantage might there be for faster detection of sad versus happy faces?

A

We see the frown face in the sea of happy faces because we are genetically brought up to see things that can cause us danger first

124
Q

What is attentional blink?

A

Attention to the first stimuli prevents awareness of the second. Imaging studies show that you unconsciously processed the 2nd image, just can’t recall it. If told to ignore the first stimuli, easily see the second.

125
Q

What is parietal-lobe neglect?

A

Patients with lesions at the right temporoparietal junction behave as if the left side of the surrounding space had ceased to exist

126
Q

What is topographic disorientation?

A

Inability to navigate using salient environmental cues, even in familiar environments

127
Q

What is frontal lobe neglect?

A

it tends to be directed only to the region related to perceiving grasping space, leaving the perception of distal space intact

128
Q

What are the major impairments of spatial ability? There are 6

A 
Topographic orientation
Egocentric disorientation
Heading disorientation
Landmark agnosia
Anterograde disorientation
Spatial distortion
129
Q

What is Egocentric disorientation?

A

Difficulty perceiving the relative location of objects with respect to the self

130
Q

What is Heading disorientation?

A

Patients are unable to plan a course to a destination, even if they can identify landmarks and describe where they want to go

131
Q

What is landmark agnosia?

A

Unable to use landmarks and information about their environment to orient themselves

132
Q

What is Anterograde disorientation

A

Patients can navigate familiar locations, but not novel ones. Unable to recognize novel visual information, such as landmarks

133
Q

What is spatial distortion?

A

Distortion in spatial perception of self – seeing themselves as too small or too large relative to their spatial world

134
Q

Where does the damage occur for someone to have egocentric disorientation?

A

posterior parietal cortex, unilaterally or bilaterally

134
Q

Where does the damage occur for someone to have heading disorientation?

A

right posterior cingulate cortex

135
Q

Where does the damage occur for someone to have landmark agnosia?

A

medial occipital lobe, specifically the lingual gyri either bilaterally or in the right hemisphere

136
Q

Where does the damage occur for someone to have anterograde disorientation?

A

right parahippocampal gyrus

137
Q

Consolidation Theory is associated with______ amnesia

A

This theory explains why new memories are lost and old ones are preserved in HPC damage (Anterograde Amnesia).

138
Q

Which form of Amnesia is associated with Multiple-Trace Theory: ?

A

All amnesia

139
Q

What are the dorsal spatial behaviour networks?

A

Dorsal Stream- originates in the visual cortex and projects through the parietal lobes to FL to guide actions

Human Neuropsychology Exam 2 (1 decks)

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