HLST200 7-12 Flashcards
Final review
Define ‘‘Cancer’’
the uncontrolled growth and spread of abnormal cells. Term cancer refers to a group of more than 100 diseases characterized by abnormal cell growth.
How does cancer (general) progress?
Normal cells follow the code of instructions embedded in DNA, cancer cells do not. If the DNA within the nucleus becomes altered, the cells become out of control. The nucleus no longer regulates growth. The abnormal cell divides to create other abnormal cells, which again divide, eventually forming neoplasms or tumours, which can either be benign (slightly abnormal, not considered life-threatening) or malignant (cancerous).
What are the 4 types of cancer?
●Carcinoma: most common kind, starts in the epithelium, the layers of cells that cover the body’s surface or line internal organs and glands
● Sarcoma: forms in the supporting or connective tissues of the body: bones, muscles, blood vessels
●Leukemia: begins in the blood-forming tissues (bone marrow, lymph nodes, and the spleen)
●Lymphoma: arises in the cells of the lymph system, the network that filters out impurities
Define neoplasm
a new abnormal growth of a tissue in the body which can be cancerous
What are the risk factors for breast cancer?
risk increases with age.
-age at menarche, age at birth of first child, breast biopsies, estrogen, family history
How can breast cancer be detected?
Combo of clinical breast exams and mammograms, routine BSE no longer recommended but should check for abnormalities.
What is the treatment for breast cancer?
Surgery, radiation, drugs
Lumpectomy, modified radial mastectomy, exemestane
What is cervical cancer?
- starts in the cells of the cervix
- Squamous cell cancer, the most common cervical cancer, starts in cells that line the surface of the cervix
What are the risk factors for cervical cancer?
Infection with certain types of HPV (not every HPV becomes cervical cancer), early age of first intercourse, multiple sex partners, genital herpes, significant exposure to second hand smoke
How can you prevent cervical cancer?
HPV vaccine and regular Pap tests
What are the risk factors for colon and rectal cancer?
age (especially those over 50), polyps (small growths on the inner wall of the colon and rectum), a family history, diet, obesity, physical inactivity, heavy alcohol consumption, smoking, and living with inflammatory bowel disease
What are colon polyps and what are the risks?
fleshy growths that usually begin growing in the epithelium lining of the bowel, common especially in older adults, many are benign, but when some are left untreated they can grow into the muscle layers underneath the epithelial lining, go through the bowel wall, and develop into an adenoma, special type of polyp that is likely to become cancerous
What is an adenocarcinoma?
malignant tumour in the epithelial tissue
Symptoms of colorectal cancer are..?
bleeding from the rectum, blood in the stool, or a change in bowel habits
Screening methods for colorectal cancer
the fecal occult blood test, detects blood in a person’s stool.
The flexible sigmoidoscopy, can detect between 50 and 65 percent of colon rectal cancers (CRC). This test examines the sigmoid colon, where 60 percent of colorectal cancers are found. A colonoscopy examines the entire colon. During this procedure, lesions or polyps can be removed. This screening method is advised for people who are at a high risk for CRC
Treatment of colorectal cancer
surgery, radiation therapy, chemotherapy
What is lung cancer
begins with development of abnormal cells in the lungs, cells form lumps and can grow into tumours, which can be benign or malignant.
What are the 2 types of lung cancer
1) non–small cell lung cancer (NSCLC): most common type and grows slowly
2) small cell lung cancer (SCLC): which grows quickly and can spread to other parts of the body
Risk factors for lung cancer
smoking, others include air pollution, family history of lung cancer, previous diagnosis of lung cancer, exposure to asbestos, arsenic, chromium, nickel, radon gas
symptoms of lung cancer
early stages usually show no symptoms but as it progresses symptoms may include:
- cough that wont go away
- shortness of breath or wheezing
- constant chest pain, especially when you cough
- frequent chest infections
- coughing up blood
- deep sense of fatigue
- loss of appetite/ unexplained weight loss
How is lung cancer diagnosed?
x-rays, ultrasounds, CT scans, MRIs, sputum cytology, biopsies of the tumour site, blood tests
Treatment of lung cancer
- Surgery is most common for non-small cell lung cancers that have not grown to a large size and have not spread to other tissues. Surgeon can remove a wedge section, the lobe of the lung containing the tumour, or the entire lung.
- Radiation treatment is used to treat a tumour. Radiation damages the cancerous cells. Unfortunately, the beam of radiation can also damage any cells in the path of the external beam. Other side effects include fatigue and skin damage where the treatment was given. Chemotherapy may also be used as a treatment option. Pills or injection are the two most common chemotherapy options
What is the leading cause of death from gynaecological cancers?
ovarian cancer
what are the 3 types of ovarian cancer?
Epithelial cell cancer: begins in the cells that cover the outer surface of the ovary.
Germ cell tumours: begin in the egg cells within the ovary. This type is more common in young women and can even develop in young children.
Stromal tumours: start in the connective tissue cells that hold the ovary together
Risk factors for ovarian cancer
family history of ovarian or breast cancer, obesity, infertility (abnormality that interferes with conception may also play a role in cancer development), low levels of transferase
symptoms of ovarian cancer
often don’t develop symptoms until advanced stages but may experience: painless swelling of the abdomen, irregular bleeding, lower abdominal pain, digestive and urinary abnormalities, fatigue, backache, bloating, and weight gain
types of skin cancer
basal cell: involving the base of the epidermis, the top level of the skin
and squamous cell (involving cells in the epidermis).
- Malignant melanoma: deadliest type of skin cancer, starts in the melanocytes (cells that produce brown pigment and colour of skin). When the skin is exposed to the sun, the melanocytes make more melanin and cause the skin to get even darker. When melanocytes cluster together they form moles. While not usually cancerous, moles can be a site for melanoma.
-can start in any part of the body where melanocytes are found, such eyes, mouth, vagina, or under the fingernails. Often metastasizes to other parts of the body and is difficult to treat once that has occurred
-occurs more often in people over 40 but is increasing in younger (particularly those who had severe sunburns as a child) early diagnosis is key for successful treatment
risk factors of skin cancer
smoking, exposure to certain hydrocarbons in asphalt, coal tar, pitch may increase risk of squamous
-other risk factors include occupational exposure to carcinogens and inherited skin disorders, such as xeroderma pigmentosum and familial atypical multiple-mole melanoma.
Individuals at increased risk for skin cancer
- fair skin, light eyes, or fair hair -a tendency to develop freckles and to burn instead of tan
- a personal or family history of melanoma
- a large number of nevi, or moles (200 or more, or 50 or more if under age 20) or dysplastic (atypical) moles
Detection of skin cancer
Skin lesions (actinic keratoses), change in existing mole or development of new and changing pigmented mole. Important indicators - ABCDE asymmetry, border, colour, diameter, evolving
Treatment of melanoma
biopsies are usually taken for a microscopic exam. Treatment is based on type of melanoma and the size, location, depth of the tumour.
-Highly curable if caught early usually with surgery alone. Once it has spread, chemotherapy with single drug or combination can temporarily shrink tumours in some people
Survival rate of metastatic melanoma
5 year survival is less than 10%
Risks of prostate cancer
increases with age, family history, exposure to the heavy metal cadmium, high number of sexual partners, and history of frequent sexually transmitted infections. An inherited predisposition may account for 5 to 10 percent of cases.
How can prostate cancer be detected
screening test that measures prostate-speific antigen (PSA) has revolutionized diagnosis: Canadian cancer society reminds us PSA cannot diagnose cancer, but can help detect a problem with the prostate. If PSA levels are high, follow up tests are needed (which can help find the cancer before it spread)
What is testicular cancer?
starts in the cell of the testicle
risk factors of testicular cancer
men with an undescended testicle, college/ uni age men at highest risk (18-35)
signs of testicular cancer
Often first sign is a slight enlargement of one testicle. May be a change in the way it feels when touched. Sometimes men with testicular cancer report a dull ache in the lower abdomen or groin, along with a sense of heaviness or sluggishness. Lumps on the testicles also may indicate cancer
Treatment for testicular cancer
generally involves surgical removal of the diseased testis, sometimes along with radiation therapy, chemotherapy, and the removal of nearby lymph nodes. The remaining testicle is capable of maintaining a man’s sexual potency and fertility. Only in rare cases is removal of both testicles necessary. Testosterone injections following such surgery can maintain potency. The chance for a cure is very high if testicular cancer is spotted early.
What are some general ways you can prevent cancer?
- Eliminating tobacco use
- Reducing alcohol consumption
- Reducing prolonged exposure to sunlight/ eliminating artificial tanning
- Reducing exposure to infections
What is type 2 diabetes?
the pancreas doesn’t produce sufficient insulin to meet the body’s needs or does not properly use the insulin it does make. It is a progressive
what is gestation diabetes mellitus
temporary condition that occurs during pregnancy. Defined as hyperglycemia or high blood sugar with the first recognition of pregnancy. It carries an increased risk of developing diabetes for both mother and child.
Example of a simple carbohydrate
lactose in milk, fructose in fruit, added sugars (in candy etc)
Example of a complex carbohydrate
nuts, grains, vegetables, beans
Difference between dietary and functional fibre
Dietary fibre is a non-digestible form of carbohydrate (naturally in plants). Functional fibres is a non-digestible form of carbohydrate that has been isolated and extracted to be added to food. Total fibre is the sum of both.
types of insoluble fibre
cellulose, lignin, and hemicellulose
saturated fats
o Saturated fats: carbon atom is saturated with hydrogen atoms ex: animal fat and butter. When you eat a diet high in saturated fats a rise in bad LDL cholesterol rises
unsaturated fats
are fats with more than one double bonded (unsaturated) carbon in the molecule.
Monounsaturated: improve bad cholesterol (olive oil and peanut oil)
Polyunsaturated fat: include omega 3 (fish, walnut, flax) which helps prevent blood clots and lower triglycerides and omega 6(safflower oil, sunflower oil, corn oil and sunflower seeds) lower LDL and may lower HDL so eat in moderation.
Trans fat: is a partially hydrogenated oil which is a unsaturated fat and can be found in baked goods and fried food. This unsaturated fat acts like a saturated fat by increasing LDL and lowering HDL cholesterol and gram for gram trans fat is twice as damaging as saturated fat. No safe amount
vitamins
essential to put macronutrients to use for growth regulation, tissue maintenance and releasing energy from foods.
symptoms of too much vitamin E
blurred vision, diarrhea, headache, nausea, etc
too much b6
can cause neurological damage, numbness in mouth and tingling in the hands
minerals
essential for vitamin absorption, help build ones and nervous system.
mineral recommended amounts
100mg for major minerals (sodium, potassium, chloride, calcium, phosphate)
10mg of trace minerals (iron, zinc, selenium, molybdenum, iodine, copper, manganese, fluoride, chromium)
1mg of calcium
Sodium
maintains proper fluid balance, regulates blood pressure, transmits muscle impulses. Too much sodium is usually okay for canadians but those with blood pressure problems and stroke must watch their intake as it can be dangerous
reasons for variety in the diet
- helps maintain healthy and interesting diet
- wider access to variety of micronutrients and phytochemical
- dilution of food toxins
- food enjoyment
- disease prevention (diabetes, cancer, CVD)
I want antioxidant benefits. Should I? Supplements or fruit?
During the normal course of functioning, the body produces “free radicals,” which react with other compounds and can lead to the damage of living cells. Antioxidants can neutralize free radicals and may lower the risk of developing cancer, heart disease, and other illnesses.
While it may be tempting to consider using antioxidant supplements, as Hales and Lauzon (2015) suggests, the evidence supporting their positive impact is conflicting and weak. Most studies that examine the effect of nutrients on a particular disease are studying foods rather than pure substances. This distinction is important because something other than antioxidants in these foods may be producing a positive effect on free radicals, or an interrelationship between several nutrients may be the underlying mechanism that leads to a particular health benefit. The best way to obtain the positive effects of antioxidants is from a diet rich in fruits and vegetables.
potential deficiencies of vegan/vegetarian diet
protein, iron, b12, calcium and vitamin D
dietary differences between men and women
they can eat same foods- but different nutritional needs. most men are bigger and taller than women and should consume more calories. Eating more means its easier for them to get the nutrients they need
how much folic acid should pregnant women take
multivitamin with 400 micrograms
benefits of folic acid for men
may cut the risk of heart disease, stroke, and colon cancer.
list factors that contribute to obesity
race and ethnicity, more calories, bigger portions, fast food, hunger and satiety, physical inactivity, passive entertainment, prenatal factors, developmental factors, genetics, emotional influences, social networks, social determinants
list symptoms of disordered eating
- Restricting calories or food intake
- Excessive or compulsive exercise
- Self-induced vomiting
- Drug use to control eating or weight gain
- Frequent weighing
- Emotional discomfort after eating
- Pre-occupation with food and calories
- Rigidity in eating and exercise schedule
- Excessive weight-lifting to increase muscularity
- Strained interpersonal relationships because of food, eating patterns, or rigid exercise schedules
- Frequent weight fluctuation
- Throat problems
- Puffy cheeks
- Swollen glands
- Callused knuckles
what is NEAT
non-exercise activity thermogenesis would be unplanned physical activities such as fidgeting and pacing.
set point theory
individual has an unconscious control system in the brain for regulating appetite to keep fat at a predetermined set point. a healthy caloric intake and regular physical activity is the only way to work with personal set points.
energy-balance equation theory
suggests that our weight will remain constant if our caloric input (energy in) and caloric output (energy out) is balanced. Any calories consumed in excess of what our body uses will be converted to fat tissue. If we do not take in enough calories, the result will be weight loss.
dietary fat theory
Some studies have shown that consuming a diet high in fat calories will result in being overweight or obese. The dietary fat theory differs from the energy-balance equation theory in that it suggests that all calories are not the same. Weight-control intervention studies that focused on low-fat diets have found promising results.
list different types of relationships
- friendships
- hooking up
- dating
- friends with benefits
intimacy
the open, trusting sharing of close, confidential thoughts and feelings—comes from the Latin word for within. Intimacy doesn’t happen at first sight or in a day or a week or a number of weeks. Intimacy requires time and nurturing; it is a process of revealing rather than hiding, of wanting to know another and to be known by that other. Although intimacy doesn’t require sex, an intimate relationship often includes a sexual relationship.
love
Social scientists have distinguished between romantic love (intimacy and passion), companionate love ( intimacy and commitment), fatuous love (passion and commitment), and consummate love ( intimacy, passion, and commitment). Mature love is a complex combination of intimacy, passion, and commitment—or consummate love, as Sternberg describes it.
types of families
traditional family that once included two heterosexual parents and children has shifted into a more complex variation of married couples that include families without children, same-sex marriages, remarriages, stepfamilies, empty- nesters, multiple generations living together, and Canadians living alone
crucial ingredients for commitment according to Robert Sternberg
- shared values
- willingness to change in response to each other
- willingness to tolerate flaws
- a match in religious beliefs
- ability to communicate effectively
health issues for GLBT individuals
- mental health
- physical health
- violence and safety
- nutritional, fitness and weight
hysterectomy
involves surgically opening the uterus and removing the fetus. This is generally done from week 16 to week 24 of the pregnancy, primarily in emergency situations when the woman’s life is in danger or when other methods of abortion are considered too risky.
examples of preconception care
Preconception care—the enhancement of a woman’s health and wellbeing prior to conception in order to ensure a healthy pregnancy and baby—includes risk assessment (evaluation of medical, genetic, and lifestyle risks), health promotion (such as good nutrition and regular physical activity), and interventions to reduce risk (such as treatment of infections and other diseases and assistance in quitting smoking or drug use).
primary causes of infertility
age, abnormal menstrual patterns, suppression of ovulation, and blocked fallopian tubes
fertility ranges
peaks between ages 20 and 30 and then drops quickly: by 20 percent after 30, by 50 percent after 35, and by 95 percent after 40