HLA Subtypes Associated with Disease

Question 1

HLA-A3

Answer 1

• Hemochromatosis

Question 2

HLA-B8

Answer 2

Don’t Be late (8), Dr. Addison, or else you’ll send my patient to the grave

• Addison disease
• Myasthenia gravis
• Graves disease

Question 3

HLA-B27

Answer 3

PAIR

• Psoriatic arthritis
• Ankylosing spondylitis
• IBD- associated arthritis
• Reactive arthritis

Question 4

HLA DQ2/DQ8

Answer 4

• Celiac disease

I ate (8) too (2) much gluten at Dairy Queen

Question 5

HLA-DR2

Answer 5

Multiple hay pastures have dirt

• Multiple sclerosis
• hay fever
• SLE
• Goodpasture syndrome

Question 6

HLA-DR3

Answer 6

2,3 S-L-E

• Diabetes mellitus type 1
• SLE
• Graves Disease
• Hashimoto thyroiditis
• Addison disease

Question 7

HLA-DR4

Answer 7

There are 4 walls in a rheum (room)

• Rheumatoid arthritis
• DM type 1
• Addison disease

Question 8

HLA-DR5

Answer 8

Hashimoto is an odd doctor (DR3, DR5)

• Hashimoto thryoiditis