HLA Flashcards
1
Q
A3
A
Hemochromatosis
2
Q
B27
A
PAIR:
Psoriasis, Ankylosing Spondylitis, IBD, Reiter’s syndrome
3
Q
DQ2/DQ8
A
Celiac disease
4
Q
DR2
A
MS, hay fever, SLE, Goodpasture’s
5
Q
DR3
A
DM 1, Grave’s disease
6
Q
DR4
A
Rheumatoid Arthritis, DM 1
7
Q
DR5
A
Pernicious anemia -> B12 deficiency, Hashimoto thyroiditis
8
Q
MHC I
A
HLA-A, HLA-B, HLA-C binds TCR & CD8 on ALL nucleated cells (not RBCs) Ag loaded in RER mediates viral immunity B2-microglobulin
9
Q
MHC II
A
HLA-DR, HLA-DP, HLA-DQ
binds TCR & CD4
only on APCs