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HIV > HIV Structure: Accessory Proteins > Flashcards

HIV Structure: Accessory Proteins Flashcards

1
Q

TAT

A

TXN

cellular and viral genes

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2
Q

REV

A

transport of viral mRNA into the cytoplasm

splicing of viral RNA to mRNA

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3
Q

NEF

A

diminishes expression of CD4 and MHC

improves virus’ ability to establish large viral load

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4
Q

VIF

A

promotes virus assembly

blocks action of APOBEC (antiviral protein)

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5
Q

VPU

A

enhances release from cell

decreases expression of CD4

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6
Q

VPR

A

arrests cells at G2 phase

enhances transport of proviral DNA into the nucleus

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HIV (2 decks)

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