HIV Drugs Flashcards

1
Q

Zidovudine

A

AZT

Nucleoside RTI

Lactic acidosis, peripheral neuropathy, anemia

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2
Q

Emtricitabine

A

FTC

Nucleoside RTI

Lactic acidosis, periph neuropathy

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3
Q

Abacavir

A

ABC

Nucleoside RTI

Lactic acidosis, periph neuropathy, hypersensitivity syndrome

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4
Q

Lamivudine

A

Nucleoside RTI

Lactic acidosis, peripheral neuropathy

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5
Q

Tenofovir

A

Nucleotide RTI

Neprho, bone toxicity, Fanconi’s

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6
Q

Efiravenz

A

1G NNRTI

Efiravenz effs with your dreams and your baby

Neuro/teratogen/resistance

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7
Q

Nevirapine

A

1G NNRTI

Neuro/teratogen/resistance

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8
Q

Etravirine

A

2G NNRTI

Rash, liver, DDI - CYP3A4

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9
Q

Lopinavir

A

PI

Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4

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10
Q

Atazanavir

A

PI

Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4

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11
Q

Ritonavir

A

PI

Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4

** used as a booster for the other PIs

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12
Q

Darunavir

A

PI

Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4

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13
Q

Enfuvirtide

A

Blocks gp41 envelope protein & prevents fusion

Binds enfelope proteins

Injectible only

Injection side effects

Used for MDR HIV

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14
Q

Maraviroc

A

CCR5 antagonist

Rockblocks CCR5

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15
Q

Raltegravir

A

Integrase inhibitor

Resistance, 2x/day, headache, rash

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16
Q

Elvitegravir

A

Integrase inhibitor

Resistance, 2x/day, headache, rash

Combo with cobicistat + tenofovir/emtricatabine