HIV Drugs Flashcards
Zidovudine
AZT
Nucleoside RTI
Lactic acidosis, peripheral neuropathy, anemia
Emtricitabine
FTC
Nucleoside RTI
Lactic acidosis, periph neuropathy
Abacavir
ABC
Nucleoside RTI
Lactic acidosis, periph neuropathy, hypersensitivity syndrome
Lamivudine
Nucleoside RTI
Lactic acidosis, peripheral neuropathy
Tenofovir
Nucleotide RTI
Neprho, bone toxicity, Fanconi’s
Efiravenz
1G NNRTI
Efiravenz effs with your dreams and your baby
Neuro/teratogen/resistance
Nevirapine
1G NNRTI
Neuro/teratogen/resistance
Etravirine
2G NNRTI
Rash, liver, DDI - CYP3A4
Lopinavir
PI
Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4
Atazanavir
PI
Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4
Ritonavir
PI
Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4
** used as a booster for the other PIs
Darunavir
PI
Dyslipidemia + atherosclerosis, GI, DDI- CYP3A4
Enfuvirtide
Blocks gp41 envelope protein & prevents fusion
Binds enfelope proteins
Injectible only
Injection side effects
Used for MDR HIV
Maraviroc
CCR5 antagonist
Rockblocks CCR5
Raltegravir
Integrase inhibitor
Resistance, 2x/day, headache, rash