HIV / AIDS Cycle

Question 1

Step 1 Binding

Answer 1

HIV cell binds to receptor on CD4 cell

Question 2

Step 2 Fusion

Answer 2

HIV envelope & CD4 cell membrane fuse; HIV enters CD4 cell

Question 3

Step 3 Reverse transcription

Answer 3

Inside CD4 cell HIV release and reverse transcriptase to convert its genetic material - HIV RNA into HIV DNA; allowing HIV to enter CD4 nucleus and combine with CD4 genetic material

Question 4

Step 4 Integrate

Answer 4

Inside CD4 cell nucelus, HIV release integrase. HIV uses integrase to insert its viral DNA into the DA=NA of CD4 cell

Question 5

Step 5 Replication

Answer 5

Once integrated into CD4 cell DNA, HIV begins to use CD4 to make long chains of HIV proteins

Question 6

Step 6 Assembly

Answer 6

New HIV protien and HIV RNA move to the surface of the cell and assemble into immature noninfectious HIV

Question 7

Step 7 Bidding

Answer 7

New HIV push itself out of host CD4 cell; rlease protease. Protease breaks up long protein shian in immature virus, creating mature virus