HIV Flashcards
How many RNA copies has the HIV virus?
2 copies
Named the 3 structural Genes of HIV
1- gap 2- pol 3- env
The gene gap codify for ?
P24 caspid protein P17 matrix protein
The gene env codify for
1- gp 120 2- gp 41
The gene pol codify for
Revrese transcriptase and Integrase
CCR5 receptor infects
Macrophages and dendritic cells early infection
CXCR4
Infects CD4 T cells late infection
Mutación homozygous para CCR5
Immunity
Mutación heterozygous para CCR5
slow course
ELISA Test
High sensitivity high FP
Western Blood
confirm the Dx bc is high specificity identifies TP
New test for HIV
p24 antigen
PCR test
viral load
Window period
Acute phase no antibodies present
Criteria to Dx AIDS
1- CD4 count < 200 2- CD4 % < 14% 3- Opportunistic Infections
CD4 < 200
PCP infection
CD4< 50
TB and MAC
CD4< 150
Histoplasma capsulatum
Meningitis in HIV
Cryptococcal
Ring enhaced lesions
Toxoplasmosis
CD4< 50
CMV retinitis
CMV on HIV fundoscopic findings
Cotton whool spot
Treatment for CMV
Ganciclovir
Named and causal agent of this lession

Owl eyes CMV infection
Progressive multifocal leukoencephalopathy causal agent on HIV
JC virus latent infection
Chronic watery diarrhea on HIV Patient
Cryptosporidosis
CD4< 100
Candidiasis Oral Trush or esophageal
Hairy leukoplakia on HIV
EBV
Kaposi sarcoma
HHV-8
Kaposi sarcoma causes
Increase on blood vessel production
named the lesion

Kaposi sarcoma
Non-Hodgkin lymphoma in HIV patients cause:
Primary CNS tumor, Large B cell lymphoma, EBV
HPV cancer on HIV patients
Squamous cell cancer of the cervix/anus
PCP prophylaxis
1- TMP- SMX if sulfa allergy Dapsone
Toxoplasmosis prophylaxis
TMP-SMX if sulfa allergy use Dapsone+Pentamidine+ leucovorin
Prophylaxis for MAC
Azythromycin weekly