HIV Flashcards

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1
Q

How many RNA copies has the HIV virus?

A

2 copies

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2
Q

Named the 3 structural Genes of HIV

A

1- gap 2- pol 3- env

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3
Q

The gene gap codify for ?

A

P24 caspid protein P17 matrix protein

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4
Q

The gene env codify for

A

1- gp 120 2- gp 41

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5
Q

The gene pol codify for

A

Revrese transcriptase and Integrase

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6
Q

CCR5 receptor infects

A

Macrophages and dendritic cells early infection

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7
Q

CXCR4

A

Infects CD4 T cells late infection

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8
Q

Mutación homozygous para CCR5

A

Immunity

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9
Q

Mutación heterozygous para CCR5

A

slow course

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10
Q

ELISA Test

A

High sensitivity high FP

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11
Q

Western Blood

A

confirm the Dx bc is high specificity identifies TP

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12
Q

New test for HIV

A

p24 antigen

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13
Q

PCR test

A

viral load

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14
Q

Window period

A

Acute phase no antibodies present

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15
Q

Criteria to Dx AIDS

A

1- CD4 count < 200 2- CD4 % < 14% 3- Opportunistic Infections

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16
Q

CD4 < 200

A

PCP infection

17
Q

CD4< 50

A

TB and MAC

18
Q

CD4< 150

A

Histoplasma capsulatum

19
Q

Meningitis in HIV

A

Cryptococcal

20
Q

Ring enhaced lesions

A

Toxoplasmosis

21
Q

CD4< 50

A

CMV retinitis

22
Q

CMV on HIV fundoscopic findings

A

Cotton whool spot

23
Q

Treatment for CMV

A

Ganciclovir

24
Q

Named and causal agent of this lession

A

Owl eyes CMV infection

25
Q

Progressive multifocal leukoencephalopathy causal agent on HIV

A

JC virus latent infection

26
Q

Chronic watery diarrhea on HIV Patient

A

Cryptosporidosis

27
Q

CD4< 100

A

Candidiasis Oral Trush or esophageal

28
Q

Hairy leukoplakia on HIV

A

EBV

29
Q

Kaposi sarcoma

A

HHV-8

30
Q

Kaposi sarcoma causes

A

Increase on blood vessel production

31
Q

named the lesion

A

Kaposi sarcoma

32
Q

Non-Hodgkin lymphoma in HIV patients cause:

A

Primary CNS tumor, Large B cell lymphoma, EBV

33
Q

HPV cancer on HIV patients

A

Squamous cell cancer of the cervix/anus

34
Q

PCP prophylaxis

A

1- TMP- SMX if sulfa allergy Dapsone

35
Q

Toxoplasmosis prophylaxis

A

TMP-SMX if sulfa allergy use Dapsone+Pentamidine+ leucovorin

36
Q

Prophylaxis for MAC

A

Azythromycin weekly

37
Q
A