HIV Flashcards
How many RNA copies has the HIV virus?
2 copies
Named the 3 structural Genes of HIV
1- gap 2- pol 3- env
The gene gap codify for ?
P24 caspid protein P17 matrix protein
The gene env codify for
1- gp 120 2- gp 41
The gene pol codify for
Revrese transcriptase and Integrase
CCR5 receptor infects
Macrophages and dendritic cells early infection
CXCR4
Infects CD4 T cells late infection
Mutación homozygous para CCR5
Immunity
Mutación heterozygous para CCR5
slow course
ELISA Test
High sensitivity high FP
Western Blood
confirm the Dx bc is high specificity identifies TP
New test for HIV
p24 antigen
PCR test
viral load
Window period
Acute phase no antibodies present
Criteria to Dx AIDS
1- CD4 count < 200 2- CD4 % < 14% 3- Opportunistic Infections