HIV Flashcards
1
Q
Initial binding to CD4 cells
- formation of neutralising Abs
A
gp120
2
Q
Binds CD4 cells - induces conformational change
- formation of neutralising Abs
A
gp41
3
Q
- formation of non-neutralising Abs
A
p24
4
Q
Chemokines produced by CD8+ to prevent entry of HIV into CD4+
A
MIP-1a
MIP-1b
RANTES
5
Q
Given to pregnant women
Reverse transcriptase inhibitor
SE: BMS
A
Zidovudine
6
Q
Anti-HIV medication
Examples: ritonavir, indinavir
SE: hyperlipidaemias, fat redistribution and T2 diabetes
A
Protease inhibitors
7
Q
ENTRY of HIV into CD4 cells
A
CXCR4/CCR5
