HIV Flashcards

0
Q

CD4 cells direct and coordinate other cells in the immune system to

A

Battle infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

HIV infects and destroys an important type of cell in the body’s immune system known as the

A

T-helper (TH) cell, also known as the CD4 cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When CD4 cells are destroyed, the body loses _____________.

A

its ability to fight off infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

HIV Infection is characterized by

A

a steady decline in the number of CD4 cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Infections that develop as a result of HIV-inflicted damage to the immune system are called

A

“opportunistic infections” or “OIs”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

When someone with HIV develops an opportunistic infection, they are diagnosed with

A

AIDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In the past, virtually all patients diagnosed with AIDS did what?

A

died within a few years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Now,withtreatment, many patients diagnosed with AIDS are _____.

A

surviving many years with the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The HIV viral load is simply a measure of the quantity of HIV

A

in a drop (mL) of a patient’s blood, and it is usually measured in copies/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In general,the-higher the viral load, the faster ______________.

A

CD4 cells are destroyed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How to handle coping____________.

A

• Ask about sources of social support – Friends, family

– Community organizations
• Offer counseling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

• What are some risk factors for acquiring HIV?

A

injection drug user (for years).

unprotected sex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Why do we care about when HIV IS contracted?

A

• Resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is resistance?

A

– Increasing transmission of drug-resistant HIV strains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When is resistance testing indicated?

A

– Resistance testing generally indicated for patients infected within the past 2-3 years, even if antiretroviral therapy is not being considered in the near future.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a flaw of resistance testing?

A

ability of currently available resistance assays to detect resistance wanes with time.

16
Q

– Loss of HIV-specific CD4 cells occurs immediately after _____.

A

• Primary HIV Infection (PHI)

17
Q

HIV Infection is characterized by a steady decline in _________.

A

the number of CD4 cells

18
Q

high risk of opportunistic infections when cd4 cels fall below

A

200 cell/mm

19
Q

How do you explain elevated transaminases?

A

Up to 19 % of HIV POSITIVE INDIVIDUALS with chronic hepatitis C HCV have negative ab titers

20
Q

HCV RNA PCR (viral load testing) is indicated if

A

Chronic hepatitis c is suspected

21
Q

What are benefits of Antiretroviral Therapy (ART)?

A

Reduced morbidity and mortality

– immune system recovery

22
Q

What are the drawbacks of Antiretroviral Therapy (ART)?

A

Toxicity
Lifestyle changes
Potential for resistance development

23
Q

Initiation of ART: Key Considerations: name

A
  • Symptoms & opportunistic infections
  • CD4 count
  • HIV viral load
  • Anticipated adherence - patient ‘readiness’