HIV Flashcards
1
Q
what is CD4
A
-CD4 receptors are the target site for HIV
-CD4 is a glycoprotein found on the surface of: T helper lymphocytes, dendritic cells, macrophages, microglial cells
2
Q
what effect does HIV infection have on the immune response
A
-reduced circulating CD4+ cells
-reduces proliferation of CD4+ cells
-reduction CD8+ (cytotoxic) T cell activation
-reduction in antibody class switching
-chronic immune activation
3
Q
how long does HIV take to establish itself as an infection
A
72 hours
