Historyyyyyy Flashcards

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1
Q

Contagion

A

Girolamo Fracastoro

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2
Q

Smallpox vaccination

A

Edward jenner

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3
Q

Attenuated chicken cholera, anthrax, rabbies vaccine

A

Louis Pasteur

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4
Q

Blood immunized with staphylococci

A

Richet and Hericourt

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5
Q

Serum of animal immunized with pseudomonas aeroginosa

A

Charrin and Rodger

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6
Q

Specificity of the protective effects of immunization

A

Pfeiffer

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7
Q

Discovered the role of leukocytes in phagocytosis

A

Ellie Metchnikoff

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8
Q

Inflammation in animals

A

Celsus

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9
Q

Changes occur in CT

A

Virchow

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10
Q

Local vascular lesion

A

Arnold and conheim

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11
Q

Action of an immune system on microbes

A

Fodor

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12
Q

Neutralizing antitoxic activity of sera

A

Emil von behring and kitasato

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13
Q

Similar neutralizing activity against snake venom

A

Calmette

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14
Q

The Pfeiffer phenomenon

A

Pfeiffer and issaef

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15
Q

Reconciled humoral and cellular theories

A

Jules bordet

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16
Q

Opsonin

A

Wright and Douglas

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17
Q

Ehrlich’s side chain theory

A

Paul ehrlich

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18
Q

First to explain the appearance of antibodies in the circulation

A

Paul ehrlich

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19
Q

Negation to ehrlichs theory

A

Bordet
Arrhenius and Madsen

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20
Q

Father of immunohematolgy
Haptens

A

Landsteiner

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21
Q

Complement Fixation Test

A

Bordet and Gengou

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22
Q

Template theory

A

Breinl and Haurowitz

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23
Q

Antibodies are immunoglobulins

A

Tiselius snd kabat

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24
Q

Variable folding theory of antibody formation

A

Pauling

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25
Q

Isoantibody

A

Bordet

26
Q

Anamnesis

A

Wassermann and von dugern

27
Q

Anaphylaxis

A

Richet and Portier

28
Q

Local necrotic lesion

A

Shwartzman

29
Q

Serum sickness

A

Von pirquet

30
Q

Allergic reaction as manifested by smooth muscle contraction

A

Schultz-dale

31
Q

Hay Fever; allergic rhinitis

A

Wolf-eisner

32
Q

Passive transfer of allergic reactivity to an allergen

A

Prausnitz-kustner

33
Q

Role of histamine in inflammatory reactions

A

Riley and west

34
Q

Self tolerance or immunologic tolerance

A

Burdet and fenner

35
Q

Felton phenomenon

A

Felton

36
Q

Acquired immune tolerance in bone marrow chimeras in mice injected with allogeneic bone marrow at or before birth

A

Billingham, brent, medaward

37
Q

Immunofluorescence

A

Coons

38
Q

Blood chimeras (in bovine twins)

A

Owen

39
Q

Antibodies are made in plasma cells

A

Fagraeus

40
Q

Classify antibody through ultracentrifugation

A

Svedberg

41
Q

Double helix of DNA

A

Watson and Crick

42
Q

2 Fab’s and 1 Fc

A

Porter

43
Q

H and L chain

A

Edelman

44
Q

Constant and variable region

A

Putnam, Hilschmann, and Craig

45
Q

First complete a.a sequence of an immunoglobulin

A

Edelman

46
Q

T cell receptor

A

Allison and Haskins

47
Q

Abs are developed in the spleen, bone marrow, and lymph nodes

A

Pfeiffer and Marx

48
Q

Immunoglobulins are heterogeneous, detected the existence of IgA

A

Grabbar and William

49
Q

Idiotypes

A

Grubb

50
Q

Allotypes

A

Oudin

51
Q

Role of thymus in immune system

A

Waksman and Yankowic

52
Q

1st to perform cholera vaccination in india

A

Haffkine

53
Q

BCG

A

Calmette and Guerin

54
Q

Tetanus toxoid

A

Lowenstein

55
Q

Diptheria toxoid

A

Glenny

56
Q

Polio vaccine

A

Salk

57
Q

Use of adjuvants in vaccines

A

Le moignic and Pinoy

58
Q

1st synthetic vaccine- diptheria vaccine

A

Alouf, chedid, and boquet

59
Q

Histocompatibility antigens on leukocytes

A

Dausset and Rapaport

60
Q

1st to produce immune serum against tissue components

A

Lindemann

61
Q

Prepared immune serum against leukocytes (anti-leukocyte antiserum)

A

Metchnikoff and besredka

62
Q

Antisera against lymphoid tissue/ anti- lymphocyte antiserum

A

Bogomoletz