History Taking Notes Flashcards
Levels of TNF-a are decreased in patients with cancer and can contribute to weight lost relating to the cancer
False
Rhinovirus and coronovirus tend to produce a scratchy throat
True
Dysphagia experienced on swallowing of both solids and liquids make a neuromuscular cause less likely
False
In heart failure breathlessness can be associated with lying down
True
Increasing fatigue maybe symptoms of sleep apnoea better
True
Cachexia is mediated by a variety of cytokines
True
TNF-a act to increase fat metabolism without sparing muscle mass
False
Amphetamines can result in rapid weight gain
False
Melanocytes are located within the basal layer of the epidermis
True
Eumelanin is the most dominant form of melanin in the skin
True
Levels of melanin in skin remain constant with varying hormone levels
False
Melasma is a condition common is pregnant women where skin patches become lighter
False
Albanism is often associated with blindness
True
It is important to ask females about their menstrual cycle when the present with skin changes
True
In infective mononucleosis caused by EBV symptoms typically take about 2-3 days to reach their peak
False
The Centor criteria is used to identify GAS infections
True
Patients with strep throat commonly present with cough
False
It is common for patients with viral throat infection to complain of a metallic taste in their mouth
False
The sensation food bolus lodged in the cervical reigon is likely to be eosophageal dysphagia
True
Emotion disorders are linked to globus pharyngeus
True
Cough due to pulmonary oedema associated with CHF is more prominent at night
True
Chronic bronchitis is defined as the presence of cough and sputum production on most days over at least a 3 month period over a year
False
Bradykinin related cough may take up to 4 weeks to resolve after discontinuing medication
True
Sputum commonly turns yellow in the presence of WBC
True
Wheeze associated with asthma tends to ease early morning and night
False
Heavy rapid breathing is characteristic of cardiac de-conditioning
True
An overdose of aspirin can produce de-conditioning and low temperature
False
Restless leg syndrome describes involuntary jerking movements of ones leg during activity
False
Epworth sleepiness scale is used to differentiate daytime sleepiness from fatigue and sleep apnoea
True
Narcolepsy typically begins in 50-60 age group
False
Sleeping without dentures decreases your risk of obstructive sleep apnoea
True
A score of 12 or more on the Epworth sleepiness scale has 100% specificity and 93.5% sensitivity for daytime sleepiness
True
Myocardial ischaemia is not a common cardiac cause of chest pain.
False
The cardiovascular system is the most common cause of chest pain presentation in general practice and to the emergency department
False
Unstable angina is described as symptoms worsening over time without being precipitated by activity
True
During a myocardial infarction pain is felt along the corresponding somatic sensory distribution (T1-4) of the chest rather than the visceral organ.
True
Pericarditis does not cause chest pain.
False
Respiratory chest pain is often pleuritic in nature.
True
The phrenic nerves originate from C3, 4, 5 and innervate the diaphragm
True
Gastrointestinal disorders that can cause chest pain include oesophageal spasm, reflux and cholecystitis.
True
Costochondritis may be described as either sharp pain or dull, aching pain.
True
Esophageal spasm and reflux readily radiate to the epigastrium but can also radiate to the right arm, much like cardiac pain.
True
Palpitation is an objective sensory symptom with the patient experiencing a conscious awareness of their heart beating.
True
Psychiatric causes of palpitations account for around 30% of cases in the emergency setting and around 45% of cases in the primary setting.
True
Conditions that predispose patients to palpitations include those that cause a parasympathetic overdrive, such as anxiety or panic states, anaemia, heart failure and some medications.
True
The most common cause of nausea and vomiting in all age groups is acute gastroenteritis.
True
Vomiting is associated with activation of the gag reflex and is mediated by cranial nerve IX and X.
True
Nausea and vomiting require a conscious perception of the toxic condition.
True
Severe abdominal pain is not an indication of an upper gastrointestinal cause of nausea and vomiting.
False
Red flags for a patient with nausea and vomiting are weight loss, blood-stained vomitus and faeculant vomitus
True
Peripheral oedema is caused by an increase in the interstitial fluid volume.
True
Hydrostatic pressure within the blood vessels pulls water and other diffusible solutes into the blood vessels.
False
An indentation of the skin is known as pitting oedema. It reflects the movement of excess interstitial fluid in response to pressure.
True
The most common cause of bilateral oedema is DVT
False
A large number of medications may precipitate ankle oedema. These include NSAIDs, steroids and antihypertensives.
True
Causes of ankle oedema include increased capillary osmotic pressure, lymphatic obstruction, hyperalbuminaemia and decreased capillary permeability.
True
Dyspepsia refers to a vague range of symptoms and is commonly seen in general practice.
True
Dyspepsia includes symptoms such as nausea, heartburn and regurgitation of food.
True
Gastric motor dysfunction refers to delayed gastric emptying secondary to the failure of the gastric fundus to relax and allow for distension.
True
The most common causes of upper abdominal pain are peptic ulcer disease, pancreatitis and biliary pain
True
Peptic ulcers penetrate the muscularis mucosae but don’t go any deeper.
False
The two major causes of peptic ulcer disease are Helicobacter pylori infection and the use of NSAIDS.
True
Most exacerbations of pancreatitis can be linked to excessive alcohol consumption or the presence of gall stones.
True
Cholecystokinin is released in response to protein in the small intestine and causes the gall bladder to contract.
False
Patients with biliary colic may also experience vomiting and diarrhoea and pain that radiates to the back.
True
Food can make pain associated with gastric ulcers better.
True
Haematemesis and malaena associated with upper abdominal pain are red flags as they are indicative that an ulcer has eroded into an artery or vein.
True
Appendicitis refers to the inflammation of the appendix, which can be due to localized ischaemia or obstruction.
True
High intraluminal pressure is thought to be the cause of diverticulum formation.
True
The majority of diverticula are located in the transverse colon.
False
Diverticulitis is the inflammation of one or many diverticulum.
True
Haemorrhage in diverticular disease can be severe resulting in per rectum bleeding, anaemia or dizziness.
True
As inflammation progresses in appendicitis it can begin to activate the pain receptors in the visceral peritoneum.
True
Mesenteric ischaemia is when vascular supply to the gastrointestinal tract is impeded and can result in diffuse abdominal pain.
True
Intestinal obstruction is caused by the interruption of normal faecal flow by some sort of occlusion.
True
Intestinal obstruction can cause dehydration.
True
When peritonitis occurs the patient is very ill with fever, tachycardia and other signs of shock.
True
In Spontaneous Bacterial Peritonitis there is usually an identifiable cause for the infection.
False
Diffuse abdominal pain associated with feeling hot and cold is suggestive of either intestinal obstruction or peritonitis due to the systemic shock that occurs after perforation.
True
Endometriosis is a condition that occurs when endometrial tissue assumes an extrauterine position within the pelvis
True
The implantation theory of endometriosis suggests that during menstruation, some of the shed endometrial cells make their war from the uterus to sites within the pelvis
True
The main concern for patients suffering from endometriosis is the increased risk of infertility inherent in endometriosis
True
Chlamydia Trachomatis and Treponema Pallidum are the most common infective agents associated with pelvic inflammatory disease
False
With a ruptured ovarian cyst, patients will often experience pain just after their expected menstruation or they may notice their period occurs later
False
The most common time for onset of symptoms of an ectopic pregnancy is within 6 - 8 weeks of their last menstruation
True
Haematemesis is the vomiting of blood and can appear as frank, red blood-stained vomitus or as “coffee-grounds: vomitus
True
The dark colouring of melaena is due to the blood having been in the gastrointestinal tract for at least 24 hours and becoming partially digested
True
Duodenal ulcers are four times more common than gastric ulcers
True
Mallory-Weiss tears are vertical tears in the mucosal lining of the oesophagus that commonly cause bleeding after an episode of forceful or persistent vomiting
True
In patients with known portal hypertension or cirrhosis the most likely source of bleeding is the oesophageal varix
True
Haemorrhagic gastropathy (erosive gastropathy or gastritis) refers to small mucosal lesions or areas of haemorrhage and can be a result of of chronic NSAID ingestion, heavy alcohol consumption, and stress
True
During the process of digestion on average a total of 9 L of fluid enters the lumen of the gastrointestinal tract, however only 1 L of this fluid is present by the time the luminal content passes through the small intestine
True
70 % of gastrointestinal secretion and absorption occurs within the small intestine
False
Changes in the mechanical phase of digestion is often the most at blame for causes of change in bowel habit
True
The migrating motor complex, which acts to clear non-digestible contents of the bowel, is initiated every 60 - 90 minutes and contractions cycle for 4 minutes
True
The mucosal walls of the large intestine do not have great absorptive capacity, but can absorb water, hence allowing for eh compaction and concentration of faecal matter
True
There are four types of diarrhoea: secretory, osmotic, inflammatory, and functional
True
Facitial diarrhoea is rarely seen in patients with eating disorders or Munchausen Syndrome
True
Antibiotic-associated diarrhoea can occur within 5 - 10 days of initiating treatment and is an overgrowth of the bacterium Clostridium Difficile
True
● constipation refers to the condition where patients experience a persistent difficulty passing stool, their bowel motions are infrequent or they have a sensation of incomplete defecation
True
● in > 90 % cases of constipation, there is an identifiable cause
False
● slow transit time is related to constipation as there is more opportunity for the gut mucosa to reabsorb the fluid from the stool and therefore create a hard, pellet-like motion
True
● patients with irritable bowel syndrome will alternate between episodes of diarrhoea and constipation
True
● some anticonvulsants like phenytoin and carbamazepine can cause constipation
True
● fibre is a partially-digestible component of a healthy diet which acts as an osmotic agent within the bowel lumen and draws water into the hardened stool to soften and improve the symptoms of constipation
True
rectorrhagia is rectal bleeding that occurs independently of defecation
True
60 % of gastrointestinal bleeding resulting in a per rectal bleed is most likely caused by a pathology in the lower gastrointestinal system (distal to the Ligament of Trietz)
False
● in rectal bleeding, the nature of the blood is usually the best indicator of anatomical source
True
● substantial bleeding is associated with angiodysplasia and diverticular disease
True
● haemorrhoids can be internal or external, and internal haemorrhoids are clinically graded 1 - VIII based upon the degree of prolapse
False
● both ischaemic and inflammatory colitis can result in rectal bleeding, however rectal bleeding is not a common presentation
True
● the colour of urine changes from day-to-day and even hour-to-hour depending on the body’s normal physiological fluid balance
True
● when the blood is seen immediately upon initiation of urine with the stream becoming clear near termination, this suggests the source of the blood is the bladder
False