History of Microbiology Flashcards
What are the first microbes to be seen the by na naked eye?
Bacteria and Protozoa
Who initiated the invention of crude microscope?
Zacharias Jansen
Who discovered the microscope?
Anton Van Leeuwenhoek
Who described microorganisms as Animacules meaning “little animals”?
Anton Van Leeuwenhoek 1623-1723
Give other discoveries of Anton Van Leeuwenhoek.
- accts of sperm
- first account of RBC
- first accounts of blood vessels
Whi developed the Cell Theory?
1665 Robert Hooke
Who developed the Theory of Spontaneous Generation?
1665 Robert Hooke
This means “living things arise from non-living things”.
Abiogenesis
Who proposed that living things arise from non-living things(Abiogenesis)?
1665 Robert Hooke
How many years did the Theory of Spontaneous Generation last?
2000 years
He is the proponent of small pox vaccine(variola).
Edward Jenner
He introduced “Biogenesis”
Rudolf Virchow (1885)
Cells arise from pre-existing cells.
BIOGENESIS
He is regarded as the •Father of Modern Bacteriology”.
Louise Pasteur
Together, they gave the final disproof for the Theory of Spontaneous Generation.
Louise Pasteur and John Tyndall (1861)
What are the other contributions of Louise Pasteur?
- Pasteurization
- Anthrax Vaccine
- Anti-rabies
The pathway of light is seen through air because it is refracted by dust particles. This is known as the __________.
Tyndall Effect
He made a specially designed box, after allowing dust particles to settle, he carefully placed the tines of sterile infusions in the box, as long as the dust os not disturbed, the infusion was sterile.
John Tyndall (1869)
What are other contributions of John Tyndall?
- Endoscope
2. Tyndallization
It means “fractional distillation”
Tyndallization
Who proved that a disease in silkworms was a result of fungal infection?
Agostino Bassi (1834)
- demontrated the transmission of child bed fever
- Ordered his students to wash their hands with chlorinated lime before examining patient.
- Reduced maternal mortality rate from 12.24%-1.27% in 2 years
Ignaz Philipp Semmelweis (1840’s)
What did Semmelweis order his students to use for handwashing?
Chlorinated lime
An English Physician credited for his attempts to prevent infection following surgery by antiseptics.
Joseph Lister(1827-1912)
What did Joseph Lister use in wound dressing and aerosole?
Carbolic acid and Phenol
It is an infection that is not present before the pt. entered the hospital or even before antibiotic was given, the infection was acquired in the hospital.
Nosocomial infection/ Hospital acquired Infection
Study of the cause of disease
Etiology
Cause of disease
Etiologic agent
A german physician known as the “Father of Bacteriologic Technique”.
Robert Koch(1843-1910)
He formulated the “Germ Theory”, which means that for every disease there is a living organism responsible.
Robert Koch (1843-1910)
What are other contributions of Robert Koch?
- anthrax
- Cholera
- MTB
