Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

3rd Year - Immunology and Serology Lecture > History of Immunology > Flashcards

History of Immunology Flashcards

1
Q
  • 430 BC
  • Plague in Athens
  • Individuals who had previously contracted the disease recovered from the illness.
A

THUCYDIDES

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What year?
Immunization by inhaling dried powders derived from the crusts of smallpox lesions

A

Chinese 1000 AD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What year?
Powdered smallpox crusts were inserted with a pin into the skin instead of inhalation

A

Chinese 15th Century

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Privately published a small booklet entitled “An inquiry into the causes and effects of the Variolae Vaccinae, a disease discovered in some of the
Western countries of England, particularly Gloucestershire and known by the name of Cow Pox”.

A

Edward Jenner

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
  • DAIRYMAID
  • She had fresh cowpox lesions on her
    hands and arms
A

Sarah Nelmes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q
  • 8-year-old boy
  • Developed mild fever and discomfort
  • After 9 days = felt cold and
    had a loss of appetite
  • Next day = he felt much better
A

James Phipps

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
  • Date when Edward Jenner inoculated James Phipps again with a matter of fresh smallpox lesion
  • NO disease was developed
  • Concluded that protection was
    COMPLETE
A

July 19, 1796

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

First one to recognize phagocytosis

A

ERNST HAECKEL (1862)
Ernst Heinrich Philip August Haeckel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Discovered the Cellular theory of immunity through Phagocytosis

A

ELIE METCHNIKOFF (1883-1905)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Discovered the live attenuated chicken cholera and anthrax vaccines

A

LOUIS PASTEUR
1880-1881

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

First report of live “attenuated” vaccine for rabies

A

LOUIS PASTEUR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Father of Immunology

A

LOUIS PASTEUR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Discovered the Humoral Theory of Immunity

A

VON BEHRING & KITASATO (1890)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

They coined the term antitoxin

A

VON BEHRING & KITASATO (1890)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Demonstrated cutaneous (or delayed-type) hypersensitivity

A

ROBERT KOCH (1891)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Discovered the Antibody Formation Theory (or Side Chain Theory of Antibody Production)

A

PAUL EHRLICH (1900)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Discovered Immediate Hypersensitivity Anaphylaxis

A

PORTIER AND RICHET (1902)

15
Q

Developed the first effective vaccine
against polio

A

JONAS SALK (1949)

15
Q

Pioneered the more easily administered
oral polio vaccine (OPV)

A

ALBERT SABIN (1949)

15
Q
  • Proved that Yellow Fever is transmitted by the bite of a mosquito
  • Developed the Yellow Fever vaccine
A

WALTER REED (1951)

15
Q

Discovered the 1st monoclonal antibodies

A

GEORGES KӦHLER (1975)

15
Q

isolated the functionally distinct T-helper 1 (Th1) and T-helper 2 (Th2) clones (the Th1 vs. Th2 model of T-helper
cell function)

A

TIM MOSMANN (1986)

16
Q

What does the T-helper 2 cells make to supress T-helper 1 cells?

A

Interleukin 10

16
Q

He developed the Human papillomavirus vaccine

A

IAN FRAZER (2005)

17
Q

Provide the Year
Arthus reaction of intermediate hypersensitivity

17
Q

Provide the Year
Hypothesis of allograft rejection

17
Q

Provide the Year
Marrack: Hypothesis of antigen-antibody binding

17
Q

Provide the Year
interferon

17
Q

Provide the Year
graft -versus-host reaction

17
Q

Provide the Year
Human leukocyte antigens ( HLA)

17
Q

Provide the Year
T- cell and B- cell cooperation in immune response

18
Q

Provide the Year
Identification of genes for T-cell receptor

A

1972
1985-1987

18
Q

Provide the Year
Identification of genes for T-cell receptor

A

1985-1987
1972

18
Q

Provide the Year
Identification of toll-like receptors

18
Q

Provide the Year
FOXP3 the gene directing regulatory T cell development

18
Q
  • A foreign substance that can stimulate the production of antibodies.
  • Immunogens (another term)
18
Q

The structures, cells, and soluble constituents of the circulating blood that allow the host to recognize and respond to antigens.

A

IMMUNE SYSTEM

18
Q

Condition of being resistant to infection

18
Q

Provide the Year
Monoclonal hepatitis B vaccine

18
Q
  • Specific glycoprotein produced in response to an antigenic challenge.
  • Immunoglobulins (another term)
18
Q

ROLE OF THE IMMUNE SYSTEM

A
  • Defending the body against infections
  • Recognizing and responding to foreign antigens
  • Defending the body against the development of tumors
19
Q

IMMUNOLOGY Consists of the following:

A
  1. The study of molecules cells organs and systems response responsible for the recognition and disposal of foreign or non-self-material
  2. How body components respond and interact
  3. The desirable and undesirable consequences of immune interaction
  4. The ways in which an immune system can be advantageously manipulated to protect against or treat disease

3rd Year - Immunology and Serology Lecture (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions