History of Immunology Flashcards
When and who discovered smallpox vaccination ?
1798 Jenner
When and who discovered phagocytosis ?
1862 Haeckel
When and who discovered live, attenuated chicken cholera and anthrax vaccine ?
1880-1881 Pasteur
When and who discovered cellular immunity through phagocytosis ?
1883-1905 Metchnikoff
When and who discovered therapeutic vaccination and first report of live “attenuated” vaccine for rabies ?
1885 Pasteur
When and who discovered humoral theory of immunity proposed ?
1890 Von Behring, Kitasata
When and who discovered demonstration of cutaneous (delayed-type) hypersensitivity ?
1891 Koch
When and who discovered passive immunization ?
1894 Emil Roux
When and who discovered antibody formation therapy ?
1900 Ehrlich
When and who discovered immediate-hypersensitivity anaphylaxis ?
1902 Portier, Richet
When and who discovered Arthus reaction of intermediate hypersensitivity ?
1903 Arthus
When and who discovered hypothesis of antigen-antibody binding ?
1938 Marrack
When and who discovered hypothesis of allograft rejection ?
1944
When and who discovered development of polio vaccine ?
1949 Salk, Sabin
When and who discovered vaccine against yellow fever ?
1951 Reed
When and who discovered graft-versus-host reaction ?
1953
When and who discovered clonal selection theory ?
1957 Burnet
When and who discovered interferon ?
1957
When and who discovered Human Leukocyte Antigens (HLAs) ?
1958-1962
When and who discovered T-cell and B-cell cooperation in immune response ?
1964-1968
When and who discovered identification of antibody molecule ?
1972 Edelman, Porter
When and who discovered first monoclonal bodies ?
1975 Köhler
When and who discovered the existence of genes that control graft rejection ?
1980 George Snell
When and who discovered the technique to identify molecules found on the surface of cells, thereby decreasing graft rejection ?
1980 Jean Dausset
When and who discovered Inheritance of an animal’s ability to make antibodies to defined molecules;
ability to respond to an antigen determining resistance and susceptibility ?
1980 Baruj Benacerraf
When and who discovered the identification of genes for T-cell receptor ?
1985-1987
When and who discovered monoclonal hepatitis B vaccine ?
1986
When and who discovered Th1 versus Th2 model of T-helper cell function ?
1986 Mosmann
When and who discovered kidney and bone marrow organ transplantation ?
1990 Murray, Thomas
When and who discovered the identification of toll-like receptors ?
1996-1998
When and who discovered FOXP3, the gene directing regulatory T-cell development ?
2001
When and who discovered the development of human papilloma virus vaccine ?
2005 Frazer
Who was the Nobel prize winner on the research of Serum antitoxins ?
Emil Von Behring 1901
Who was the Nobel prize winner on the research of Cellular immunity in TB ?
Robert Koch 1905
Who was the Nobel prize winner on the research of phagocytosis ?
Elie Metchnikoff 1908
Who was the Nobel prize winner on the research of immunity ?
Paul Ehrlich 1908
Who was the Nobel prize winner on the research of anaphylaxis ?
Charles Richet 1913
Who was the Nobel prize winner on the research of complement ?
Jules Bordet 1919
Who was the Nobel prize winner on the research of Human blood group antigens ?
Karl Landsteiner 1930
Who was the Nobel prize winner on the research of discovery of immunologic tolerance ?
Macfarlane Burnet, Peter Medawar 1960
Who was the Nobel prize winner on the research of structure of antibodies ?
Gerald Edelman, Rodney Porter 1972
Who was the Nobel prize winner on the research of Radioimmunoassay ?
Rosalyn Yalow 1977
Who was the Nobel prize winner on the research of Major histocompatibility complex ?
George Snell, Jean Dausset, Baruj Benacerraf 1980
Who was the Nobel prize winner on the research of immunoregulation ?
Niels Jerne 1984
Who was the Nobel prize winner on the research of Monoclonal antibody ?
Georges Koehler, Cesar Milstein 1984
Who was the Nobel prize winner on the research of antibody diversity ?
Susumu Tonegawa 1987
Who was the Nobel prize winner on the research of transplantation ?
Edward Donnall Thomas, Joseph Murray 1991
Who was the Nobel prize winner on the research of Cytotoxic T cell recognition of virally infected cells ?
Peter Doherty, Rolf Zinkernagel 1996
Who was the Nobel prize winner on the research of prions ?
Stanley Prusiner 1997
Who was the Nobel prize winner on the research of signal transduction ?
Gunter Blobel 1999
Who was the Nobel prize winner on the research of HIV ?
Françoise Barré – Sinoussi, Luc Montagnier 2008
