History of BB

Question 1

other term for Blood Banking

Answer 1

Immunohematology

Question 2

study about antigens and antibodies related to blood groups

Answer 2

Blood Banking

Question 3

first blood transfusion patient

Answer 3

1492: Pope Innocent VII

Question 4

he developed Haemolytic Transfusion Reaction after failed blood tranfusion

Answer 4

1492: Pope Innocent VII

Question 5

animal to man blood transfusion

Answer 5

1667: Denys and Emmerez

Question 6

animal blood transfusion donor

Answer 6

Sheep (1667: Denys and Emmerez)

Question 7

Sodium Phosphate as an anticoagulant

Answer 7

1869: Braxton Hicks

Question 8

Father of Blood Banking

Answer 8

1900: Karl Landsteiner

Question 9

Discovered ABO Blood Groups and Rh Blood group

Answer 9

1900: Karl Landsteiner

Question 10

antigen present in blood type O

Answer 10

H antigen

Question 11

Bombay phenotype

Answer 11

Type O

Question 12

Law of Heredity

Answer 12

1865: Gregor Mendel

Question 13

Phenomenon of Isoimmunization of goats

Answer 13

Ehrlich and Morgenroth

Question 14

an antibody that activates a complement leading to red cell lysis

Answer 14

Immune hemolysin (Ehrlich and Morgenroth)

Question 15

Discovered type AB

Answer 15

1902: Descatelo and Sturle

Question 16

1st to succeed in vein to vein transfusion of blood

Answer 16

1913: Lindemann

Question 17

Discovered the use of multiple syringes with a special canula that can puncture the skin leading to the vein

Answer 17

1913: Lindemann

Question 18

Disadvantages of drawbacks

Answer 18

1. Time consuming
2. Very complicated
3. Need of few skilled assistants

(1913: Lindemann)

Question 19

Syringe-valve apparatus

Answer 19

Unger

Question 20

Anticoagulant discovered by Hustin in 1914

Answer 20

Sodium Citrate

Question 21

Glucose acts as a __________

Answer 21

Diluent / suspending medium (1914: Hustin)

Question 22

stated the correct min. amount of anticoagulant to blood

Answer 22

1915: Lewisohn

Question 23

ratio for anticoagulant to blood

Answer 23

1:9 (1915: Lewisohn)

Question 24

Citrate Dextrose Solution

Answer 24

1916: Rous and Turner

Question 25

role of Citrate Dextrose Solution under 1916: Rous and Turner

Answer 25

preservative

Question 26

Discovered the Rh blood group

Answer 26

1939-1940: Lansteiner and Weiner

Question 27

Blood from Rhesus monkeys were injected to __________

Answer 27

Rabbits (1939-1940: Lansteiner and Weiner)

Question 28

Rh +

Answer 28

D antigen | immunogenic/reactive

Question 29

Rh -

Answer 29

C, c, E, e antigens | non immunogenic/nonreactive

Question 30

Acid Citrate Dextrose

Answer 30

1943: Loutit and Mollison

Question 31

1957: Gibson

Answer 31

Citrate Phosphate Dextrose

Question 32

1970: Beutler

Answer 32

Additive solutions

Question 33

Saline Adenine Glucose

Answer 33

1971: Hogman

Question 34

1980: Lovric

Answer 34

CP2D + SAG

Question 35

lifespan of CP2D

Answer 35

21 days (Lovric)

Question 36

lifespan of CPDA-1

Answer 36

35 days

Question 37

Additive solutions

Answer 37

1. Saline: to suspend the solute 2. Adenine: to increase survival of RBC 3. Glucose: to provide energy for RBC 4: Mannitol: RBC membrane stabilizing agent

Question 38

Study of transmission of inherited characteristics/traits from parents

Answer 38

Genetics

Question 39

Genes present

Answer 39

Genotype

Question 40

Genes expressed

Answer 40

Phenotype

Question 41

Total genetic composition of an individual; maternally and paternally derived genes

Answer 41

Genotype

Question 42

Possible genotypes for A1

Answer 42

A1A1, A1O, A1A2

Question 43

Possible genotypes for A2

Answer 43

A2A2, A2O

Question 44

Possible genotype for A1B

Answer 44

A1B

Question 45

Possible genotype for A2B

Answer 45

A2B

Question 46

Possible genotypes for B

Answer 46

BB, BO

Question 47

Possible genotypes for O

Answer 47

OO

Question 48

Chromosome # 1

Answer 48

Rh, Duffy

Question 49

Chromosome # 4

Answer 49

MNS

Question 50

Chromosome # 7

Answer 50

Kell

Question 51

Chromosome # 9

Answer 51

ABO

Question 52

Chromosome # 18

Answer 52

Kidd

Question 53

Chromosome # 19

Answer 53

H, Lewis, Lutheran

Question 54

Chromosome # 22

Answer 54

P1

Question 55

Blood group resistant to malaria

Answer 55

Duffy

Question 56

Most important system in transfusion and transplantation therapy

Answer 56

ABO blood group system

Question 57

Inherited thru codominance

Answer 57

ABH genes

Question 58

Anti A

Answer 58

Methylene Blue

Question 59

Anti B

Answer 59

Acriflavine

Question 60

Anti AB and Anti D

Answer 60

Colorless

Question 61

alternative for NSS solution

Answer 61

22% Bovine Albumin or Bovine Serum albumin

Question 62

Reading time for slide method

Answer 62

2 mins

Question 63

Why is tube method the preferred one?

Answer 63

it does not dry up easily

Question 64

Cell Typing

Answer 64

Direct/ Forward

Question 65

Serum Typing

Answer 65

Reverse/ Indirect

Question 66

Specimen for Backward Typing

Answer 66

Serum

Question 67

Reagent in direct method

Answer 67

Antisera

Question 68

Reagent in indirect typing

Answer 68

Known cells

Question 69

shelf life of known cell suspension

Answer 69

24 hrs

Question 70

typing sera

Answer 70

Antigen

Question 71

Known cells

Answer 71

Antibodies

Question 72

Agglutination is due to

Answer 72

ag-ab reaction

Question 73

substance found in the surface of the blood

Answer 73

ABO Secretor cells