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BLOOD BANKING LEC > History of BB > Flashcards

History of BB Flashcards

1
Q

other term for Blood Banking

A

Immunohematology

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2
Q

study about antigens and antibodies related to blood groups

A

Blood Banking

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3
Q

first blood transfusion patient

A

1492: Pope Innocent VII

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4
Q

he developed Haemolytic Transfusion Reaction after failed blood tranfusion

A

1492: Pope Innocent VII

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5
Q

animal to man blood transfusion

A

1667: Denys and Emmerez

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6
Q

animal blood transfusion donor

A

Sheep (1667: Denys and Emmerez)

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7
Q

Sodium Phosphate as an anticoagulant

A

1869: Braxton Hicks

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8
Q

Father of Blood Banking

A

1900: Karl Landsteiner

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9
Q

Discovered ABO Blood Groups and Rh Blood group

A

1900: Karl Landsteiner

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10
Q

antigen present in blood type O

A

H antigen

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11
Q

Bombay phenotype

A

Type O

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12
Q

Law of Heredity

A

1865: Gregor Mendel

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13
Q

Phenomenon of Isoimmunization of goats

A

Ehrlich and Morgenroth

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14
Q

an antibody that activates a complement leading to red cell lysis

A

Immune hemolysin (Ehrlich and Morgenroth)

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15
Q

Discovered type AB

A

1902: Descatelo and Sturle

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16
Q

1st to succeed in vein to vein transfusion of blood

A

1913: Lindemann

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17
Q

Discovered the use of multiple syringes with a special canula that can puncture the skin leading to the vein

A

1913: Lindemann

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18
Q

Disadvantages of drawbacks

A
  1. Time consuming
  2. Very complicated
  3. Need of few skilled assistants

(1913: Lindemann)

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19
Q

Syringe-valve apparatus

A

Unger

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20
Q

Anticoagulant discovered by Hustin in 1914

A

Sodium Citrate

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21
Q

Glucose acts as a __________

A

Diluent / suspending medium (1914: Hustin)

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22
Q

stated the correct min. amount of anticoagulant to blood

A

1915: Lewisohn

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23
Q

ratio for anticoagulant to blood

A

1:9 (1915: Lewisohn)

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24
Q

Citrate Dextrose Solution

A

1916: Rous and Turner

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25
Q

role of Citrate Dextrose Solution under 1916: Rous and Turner

A

preservative

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26
Q

Discovered the Rh blood group

A

1939-1940: Lansteiner and Weiner

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27
Q

Blood from Rhesus monkeys were injected to __________

A

Rabbits (1939-1940: Lansteiner and Weiner)

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28
Q

Rh +

A

D antigen

immunogenic/reactive

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29
Q

Rh -

A

C, c, E, e antigens

non immunogenic/nonreactive

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30
Q

Acid Citrate Dextrose

A

1943: Loutit and Mollison

31
Q

1957: Gibson

A

Citrate Phosphate Dextrose

32
Q

1970: Beutler

A

Additive solutions

33
Q

Saline Adenine Glucose

A

1971: Hogman

34
Q

1980: Lovric

A

CP2D + SAG

35
Q

lifespan of CP2D

A

21 days (Lovric)

36
Q

lifespan of CPDA-1

A

35 days

37
Q

Additive solutions

A
  1. Saline: to suspend the solute
  2. Adenine: to increase survival of RBC
  3. Glucose: to provide energy for RBC
    4: Mannitol: RBC membrane stabilizing agent
38
Q

Study of transmission of inherited characteristics/traits from parents

A

Genetics

39
Q

Genes present

A

Genotype

40
Q

Genes expressed

A

Phenotype

41
Q

Total genetic composition of an individual; maternally and paternally derived genes

A

Genotype

42
Q

Possible genotypes for A1

A

A1A1, A1O, A1A2

43
Q

Possible genotypes for A2

A

A2A2, A2O

44
Q

Possible genotype for A1B

A

A1B

45
Q

Possible genotype for A2B

A

A2B

46
Q

Possible genotypes for B

A

BB, BO

47
Q

Possible genotypes for O

A

OO

48
Q

Chromosome # 1

A

Rh, Duffy

49
Q

Chromosome # 4

A

MNS

50
Q

Chromosome # 7

A

Kell

51
Q

Chromosome # 9

A

ABO

52
Q

Chromosome # 18

A

Kidd

53
Q

Chromosome # 19

A

H, Lewis, Lutheran

54
Q

Chromosome # 22

A

P1

55
Q

Blood group resistant to malaria

A

Duffy

56
Q

Most important system in transfusion and transplantation therapy

A

ABO blood group system

57
Q

Inherited thru codominance

A

ABH genes

58
Q

Anti A

A

Methylene Blue

59
Q

Anti B

A

Acriflavine

60
Q

Anti AB and Anti D

A

Colorless

61
Q

alternative for NSS solution

A

22% Bovine Albumin or Bovine Serum albumin

62
Q

Reading time for slide method

A

2 mins

63
Q

Why is tube method the preferred one?

A

it does not dry up easily

64
Q

Cell Typing

A

Direct/ Forward

65
Q

Serum Typing

A

Reverse/ Indirect

66
Q

Specimen for Backward Typing

A

Serum

67
Q

Reagent in direct method

A

Antisera

68
Q

Reagent in indirect typing

A

Known cells

69
Q

shelf life of known cell suspension

A

24 hrs

70
Q

typing sera

A

Antigen

71
Q

Known cells

A

Antibodies

72
Q

Agglutination is due to

A

ag-ab reaction

73
Q

substance found in the surface of the blood

A

ABO Secretor cells

BLOOD BANKING LEC (1 decks)

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