History - medicine Flashcards

1
Q

Industrial revolution

A

Period from 1750 - 1900 when Britain changed from a country based on agriculture to industry

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2
Q

Anaesthetic

A

Substance that stops you feeling pain

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3
Q

Antiseptic

A

A substance that is applied to a wound to kill germs

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4
Q

Chloroform

A

Simpson discovered that this chemical could be used to prevent people from feeling pain in surgery

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5
Q

Carbolic acid

A

A spray that was used to clean sewers - lister found that this could be used to kill germs and prevent infection in surgery

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6
Q

Compulsory

A

When people are required to do something by law

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7
Q

Microbe

A

Bacteria that can cause disease

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8
Q

Epidemic

A

A widespread outbreak of disease

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9
Q

Cesspit

A

A place for collecting and storing sewage

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10
Q

Tax

A

Money collected by the government

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11
Q

What was the most widely accepted cause of disease before 1861?

A

Miasma (bad air)

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12
Q

When did Pasteur publish germ theory?

A

1861

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13
Q

Who published germ theory?

A

Louis pasteur

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14
Q

When did Robert Koch find the bacterium that was causing a disease called anthrax?

A

1876

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15
Q

When was the first time anyone identified a specific bacteria that caused an individual disease?

A

1876

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16
Q

Who found the bacterium causing anthrax?

A

Robert koch

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17
Q

When was the bacteria causing typhoid discovered?

A

1882

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18
Q

When was the bacteria causing the plague discovered?

A

1894

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19
Q

Who noticed that milkmaids who caught cowpox didn’t catch smallpox?

A

Edward Jenner

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20
Q

When did edward Jenner publish his work describing how to prevent smalllpox?

A

1798

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21
Q

In Edward jenners published work, how did he describe how to prevent smallpox?

A

By infecting people with cowpox first, to make them immune (vaccination)

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22
Q

When was smallpox completely wiped out?

A

In the 1970s

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23
Q

What was the problem with Edward jenners work?

A

He did not know how vaccination worked so it could only be used to prevent smallpox

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24
Q

When did the government make it compulsory to be vaccinated for smallpox?

A

1853

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25
Q

When was the first successful vaccination since smallpox and what was it for?

A

1885 for rabies

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26
Q

When was there a cholera outbreak in London?

A

1854

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27
Q

What did John snow say regarding the cholera outbreak?

A

That it was caused by dirty water

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28
Q

What did John snow do to investigate the cholera outbreak?

A

He mapped out the deaths in his local area and found that most deaths were of people who got their water from the broad street pump. He removed the pump and there were no more deaths in the area

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29
Q

What was later found regarding the broad street pump?

A

That a cesspit was leaking into the water

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30
Q

Why did many people not believe snow?

A

Because they believed that miasma caused disease

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31
Q

When were Snows findings accepted?

A

After the germ theory was published

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32
Q

When did the government introduce the first public health act?

A

1848

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33
Q

Why was the 1848 public health act introduced?

A

To improve towns but most of the rules weren’t compulsory so made little diference

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34
Q

What did the 1875 public health act state?

A

That it was compulsory for local councils to improve sewers and drainage, provide fresh water supplies, and to appoint medical officers to insert public health facilities

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35
Q

Give two reasons for why the 1875 public health act was introduced?

A

1) germ theory had proved that there was a scientific link between dirt and disease

2) in 1857 working men received the vote which meant that the government had to pass laws to help everyone

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36
Q

Which war was Florence nightingale a nurse in?

A

The Crimean war

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37
Q

What was Florence nightingale appalled by? What did she concentrate on?

A

The dirty conditions, she concentrated on cleaning the hospitals and the death rate fell.

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38
Q

Wheee and when did Florence nightingale set up her first ‘nightingale school for nurses’

A

In Britain, 1860

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39
Q

When did Florence nightingale write ‘notes on nursing’?

A

1859, leading to better trained nurses

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40
Q

When did Florence nightingale write ‘notes on hospitals’?

A

1863

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41
Q

What did nightingale emphasise due to her belief that miasma caused disease?

A

Hygiene and good air

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42
Q

What did nightingale make sure of in hospitals?

A

That they had good sanitation, ventilation, food supplies, clean clothing and washing facilities

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43
Q

When did James Simpson discover that chloroform was an effective anaesthetic?

A

1847

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44
Q

Who discovered chloroform? (Anaesthetic)

A

James simpson

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45
Q

When was surgery’s ’black period’

A

1850s - 1870s

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46
Q

What was the surgery’s ’black period’?

A

When the number of patients dying in surgery increases (mostly due to infection’)

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47
Q

When did Joseph lister discover that carbolic acid can be used as an antiseptic?

A

1867

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48
Q

Who discovered that carbolic acid could be used as an antiseptic?

A

Joseph lister

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49
Q

After the discovery of carbolic acid, what was the difference in death rates in operations?

A

Death rates in operations fell from 46% in 1866 to 15% in 1870

50
Q

When has aseptic surgery developed

A

By the late 1980s

51
Q

What is meant by aseptic surgery?

A

Removing all germs from the operating theatre?

52
Q

How did the government start taking in a bigger role in medicine in the 1800s

A

They gave Jenner £30000 to develop vaccinations and made them compulsory. They also stopped taxing soap so more people could afford it in 1853. They a.so introduced laws to improve public health

53
Q

How did new technology lead to progress in the industrial period?

A

Listers microscope helped identify bacteria. New engineering allowed Bazalgette to design and build the new London sewer in 1858

54
Q

Who is bazalgette?

A

He designed and built the new London sewer in 1858

55
Q

How did the discovery of the germ theory in 1861 lead to progress in medicine?

A

It meant that people now understood the actual cause of disease and treatments and preventative methods could be developed

56
Q

What time period were individuals such as: Koch, Pasteur, lister, nightingale and Jenner from?

A

The industrial / enlightenment period

57
Q

What is a magic bullet?

A

Chemical that targets a specific germ

58
Q

What is an antibiotic?

A

Drug made from bacteria that kills other bacteria and so cures an infection

59
Q

What is streptococci and staphylococci?

A

Harmful bacteria that caused infections

60
Q

What is a gene?

A

Parts of a cell that determines how our bodies look and work, they are passed from parents to children

61
Q

What is an electron microscope?

A

Microscopes which allowed people to see much smaller objects in much finer detail

62
Q

What is crystallography ?

A

Crystallography uses radiation to take high power x ray photos

63
Q

What is a genome?

A

Complete set of genes in a living creature

64
Q

What two improvements in technology allowed scientists to discover that DNA existed and somehow controlled what we are like?

A

1) electron microscopes
2) better x rays using crystallography

65
Q

When did crick and Watson discover the structure of DNA?

A

1953

66
Q

Who discovered the structure of DNA?

A

Crick and Watson

67
Q

What did crick and Watson prove?

A

That DNA was present in every cell and showed how it passed information on from parents to children

68
Q

Who did crick and Watson work with?

A

Rosalind Franklin and Maurice Wilkins

69
Q

What was Rosalind Franklin the first to develop?

A

A technique to photograph DNA

70
Q

When did the human genome project start and end?

A

1986 - 2001

71
Q

What was the purpose of the human genome project?

A

To identify the purpose of each gene in the body

72
Q

What have scientists discovered since the human genome project

A

Scientists have discovered specific genes which pass on particular conditions such as downs syndrome

73
Q

When did Paul Ehrlich develop the first chemical drug that killed bacteria inside the body? what was it called?

A

1909, Salvarsan 606

74
Q

What did Paul Ehrlich develop in 1909?

A

First chemical drug that killed bacteria inside the body

75
Q

What was the problem with Salvarsan 606?

A

It not only killed the bacteria that caused syphilis but also the patient

76
Q

What did Domagk find in the 1930s?

A

That prontosil cured blood poisoning in mice and humans

77
Q

What was Prontosil?

A

The first chemical care

78
Q

What did scientists discover was the important chemical in both Salvarsan and Prontosil?

A

Sulphonamide

79
Q

Drug companies developed sulphonamide cures for disease such as……..?

A

Pneumonia and scarlet fever

80
Q

Who accidentally discovered penicillin?

A

Alexander flemming

81
Q

When did Alexander Fleming accident,y discover penicillin?

A

1928

82
Q

What did Fleming notice when penicillin mould had grown in a petri dish?

A

That around the mould the staphylococci bacteria had dissapeared

83
Q

When did Fleming write about how penicillin can used to fight infection in a medical journal?

A

1929

84
Q

What did Fleming write about in his 1929 medical journal?

A

How penicillin can be used to fight infection

85
Q

Who decided to carry out the research on penicillin?

A

Florey and chain

86
Q

When did Florey and chain decide to carry out the research on penicillin?

A

1938

87
Q

What did Florey and chain find with the governments money?

A

That penicillin could help mice recover from imfectiom

88
Q

What did Florey and chain do in 1941?

A

Test penicillin on a policeman who had an infection

89
Q

What went wrong when Florey and chain tested penicillin on an infected policeman

A

They ran out of antibiotics after five days and he died

90
Q

What did the American government do during ww2 since penicillin cost a lot of money to mass produce?

A

Gave loans to drug companies so that they could mass produce penicillin to use to treat wounded soldiers

91
Q

When was the NHS set up?

A

July 1948

92
Q

What was the purpose of the NHS when it was created in 1948?

A

To deliver free care for all since around 8 million people had NEVER seen a doctor before this

93
Q

What did the labour government do when the nhs was set up?

A

Rebuild many hospitals and supply doctors and nurses with new, better equipment

94
Q

Give an example of specialist skills nurses developed when the nhs was set up?

A

Caring for cancer patients who had undergone chemotherapy

95
Q

What happened as a result of the nhs ?(hint.. pregnancy)

A

There were fewer women dying in childbirth and life expectancy increased

96
Q

Who discovered blood groups?

A

Karl landsteiner

97
Q

Who are forced to check care in hospitals and force hospitals to make improvements if necessary?

A

The care quality commission

98
Q

When did Karl Landsteiner discover blood groups?

A

1901

99
Q

How was the problem of solving blood solved in WW1?

A

Adding sodium citrate to prevent clotting and storing the blood at a cool temperature

100
Q

Who discovered x rays In 1895?

A

Wilhelm rontgen

101
Q

When did wilhelm rontgen discover x rays

A

1895

102
Q

How did x rays revolutionise medicine?

A

They changed the care of pregnant woman as it became easier to monitor the development of the baby in the womb

They were also used a lot during ww1 to locate bullets

103
Q

Who discovered radium?

A

Marie curie

104
Q

How has radium revolutionised medicine?

A

Been used to diagnose and treat cancers (in radiotherapy)

105
Q

When was the first kidney transplant?

A

1954

106
Q

When was the first liver transplant?

A

1963

107
Q

When was the first heart transplant?

A

1967

108
Q

What is keyhole surgery?

A

When surgeons operate through a tiny hole using an endoscope (which is controlled by surgeons using a miniature camera) fibre optic cables and computers

109
Q

What does keyhole surgeries allow surgeons to do?

A

Rejoin vessels and nerves

110
Q

When were anaesthetics developed that could be injected into the bloodstream?

A

1930s

111
Q

When was a vaccine for polio made?

A

1954

112
Q

When was a vaccine for measles made?

A

1964

113
Q

What does genetic screening do?

A

Can identify potential illness allowing doctors to act before an illness has developed

114
Q

What has the NHS created to encourage people to adopt healthier lifestyles?

A

Health campaigns

115
Q

Give an example of a campaign the NHS has created to encourage people to adopt healthier lifestyles?

A

‘Five a day’

116
Q

What is legislation?

A

Reducing pollution and increasing food safety

117
Q

Give 4 factors that led to progress in medicine

A

Technology, changes to the franchise, ww1, ww2

118
Q

How did technology lead to progress in medicine ?

A

More powerful microscopes allowed for the discover of dna.

Advances in tech have allowed for more complex surgery to be developed
E.g. keyhole surgery

119
Q

How did changes to the franchise lead to progress in medicine?

A

In 1918 all men and women over 30 could vote.
In 1928 this was given to adults over the age of 21

This meant that the government had to win the support of everybody

120
Q

How did ww1 lead to progress in medicine?

A

There were many diff injuries so there was a need to develop new treatments

Treatments also had to be adapted for the western front, leading to the development of storing blood.

121
Q

How did ww2 lead to progress in medicine?

A

Made the government out more money into developing treatment

E.g. the American government put a lot of money into the development of penicillin to treat soldiers

122
Q

Name individuals that led to progress in medicine in the 20th century

A

Curie, crick, Watson, Franklin, Watkins, Fleming