history and intro Flashcards
The central dogma of DNA:
The central dogma of DNA:
DNA replication»transcription»RNA»translation
»protein
how did Fredric Michener 1871 discover genes
studying pus chemical composition. Wash off bandages with salt solution> treat with HCL to lyse cells> remove lipids with ether>dissolve residue with alkaline solution> obtain DNA precipitate with acid. Called mysterious stuff nuclein high in phosphate.
what did Erwin Chargaff
purifying various sources of DNA finds and comparing total amount of each base developing base pair rule A+T C+G
how did Rosalind Franklin wattson and crick contribute to our understanding of DNA?
Rosalind franklin- measuring diffraction of X-rays by Dna. hypothesis double asymmetric double helical structure.(1953)
Watson and Crick add antiparallel suggestion and talk about base pairing system.(1953)