history and intro Flashcards

1
Q

The central dogma of DNA:

A

The central dogma of DNA:
DNA replication»transcription»RNA»translation
»protein

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2
Q

how did Fredric Michener 1871 discover genes

A

studying pus chemical composition. Wash off bandages with salt solution> treat with HCL to lyse cells> remove lipids with ether>dissolve residue with alkaline solution> obtain DNA precipitate with acid. Called mysterious stuff nuclein high in phosphate.

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3
Q

what did Erwin Chargaff

A

purifying various sources of DNA finds and comparing total amount of each base developing base pair rule A+T C+G

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4
Q

how did Rosalind Franklin wattson and crick contribute to our understanding of DNA?

A

Rosalind franklin- measuring diffraction of X-rays by Dna. hypothesis double asymmetric double helical structure.(1953)
Watson and Crick add antiparallel suggestion and talk about base pairing system.(1953)

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