History Flashcards by Kirby Leij Santos

Q

430 BC

A

Thucydides (Athens) “immune”

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Q

1000 AD

A

inhaling dried powders from smallpox lesions

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Q

1700’s

A

milk maids were immune to smallpox because of their contraction of cowpox

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Q

1798

A

Edward Jenner

smallpox vaccine

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Q

1862

A

Haeckel

Phagocytosis

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Q

1880-1881

A

Louis Pasteus

cholera and anthrax vaccine; germ theory

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Q

1882-1905

A

Metchnikoff

cellular immunity through phagocytosis

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Q

1885

A

Pasteur’s vaccine for rabies

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Q

1890

A

Von Behring, Kitasata’s

humoral theory of immunity

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Q

1891

A

Koch’s

demonstration of cutaneous hypersensitivity

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Q

1900

A

Ehrlich’s

antibody formation theory

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Q

1902

A

Portier and Richet’s

immediate-hypersensitivity anaphylaxis

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Q

1903

A

Arthus

reaction of intermediate hypersensitivity

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Q

1938

A

Marrack’s

hypothesis of antigen-antibody binding

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Q

1944

A

Allograft rejection hypothesis

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Q

1949

A

Salk and Sabin’s

polio vaccine

Q

1951

A

Reed’s

vaccine for yellow fever

Q

1956

A

graft-vs-host reaction

Q

1957

A

Burnet’s

clonal selection theory

Q

1957

A

Interferon

Q

1958

A

Human leukocyte antigens (HLAs)

Q

1964-1968

A

T-cell and B-cell cooperation in immune response

Q

1972

A

Antibody molecule

Q

1975

A

Kohler’s

first monoclonal antibodies

Q

1985-1987

A

Genes for T cell receptor

Q

1986

A

Monoclonal Hepatitis B vaccine

Q

1986

A

Mosmann’s

Th1 vs Th2 model of helper cell function

Q

1996-1998

A

Identification of toll-like receptors

Q

2001

A

FOXP3, the gene directing regulatory of human T cell development

Q

2005

A

Frazer’s

HPV vaccine