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IH LEC > History > Flashcards

History Flashcards

1
Q

Received blood from three individuals (hemophilia)

A

Pope Innocent VII (1492)

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2
Q

discovered blood circulation; afterward, the earliest known blood transfusion was
attempted

A

William Harvey (1628)

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3
Q

Performed the first animal-to-human transfusion on June 15, 1667, by bloodletting a 16-year-old boy and
exchanging three (3) ounces of boy’s blood for nine (9) ounces of lamb’s blood

A

Jean Baptiste Denis (June 15, 1667)

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4
Q

who received calf’s blood and then suffered a transfusion reaction but
survived and became well

A

Anton Mauroy

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5
Q

first recorded successful blood transfusion occurs in England; keeps dogs alive by blood
transfusion from other dogs

A

Richard Lower (1665)

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6
Q

Transfused sheep blood to a student

A

Richard Lower (1667)

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7
Q

performed the first human-to-human transfusion in 1795 (not confirmed)

A

Philip Syng Physick (1795)

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8
Q

subsequently performed and published a set of animal experiments that proved that the
donor and recipient must be of the same species

A

John Henry Leacock

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9
Q

Successfully transfused a woman dying from postpartum hemorrhage with blood from her husband

A

James Blundell (August 1825)

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10
Q

he performed ten transfusions, five of which proved beneficial to his patients, and
published these results

A

James Blundell (bet 1825 and 1830)

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11
Q

first successful whole blood transfusion to treat hemophilia in 1840

A

Samuel Armstrong Lane (1840)

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12
Q

first surgery using direct blood transfusion

A

George Washington Crile (1906)

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13
Q

Observed red cell lysis in the blood of a woman who died after receiving a transfusion of sheep blood

A

Emil Ponfick

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14
Q

Incompatible transfusions were associated with hemorrhage and congestion of the kidneys, lungs, and liver

A

Emil Ponfick

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15
Q

Incompatible transfusions were associated with hemorrhage and congestion of the kidneys, lungs, and liver

A

Emil Ponfick

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16
Q

observation that human red cells would lyse when mixed in vitro with the sera of other animals

A

Leonard Landois

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17
Q

Set the stage for the study of the immunologic basis of blood incompatibility

A

Leonard Landois

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18
Q

Discovered the ABO blood group and explained the serious reactions that occur in humans as a result of
incompatible transfusion

A

Karl Landsteiner (1901)

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19
Q

Noticed that human blood mixed in test tubes with other specimens of human blood sometimes resulted in
agglutination

A

Karl Landsteiner (1901)

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20
Q

By incubating red cells from some individuals with serum from others, he identified agglutination patterns,
leading to the initial identification of three blood groups: A, B, and C

A

Karl Landsteiner (1901)

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21
Q

Discovered blood type AB

A

Alfred von Descatello and Adriano Sturlie (1902)

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22
Q

Discovered subgroups of A

A

von Dungern/Dungren and Hirszfeld (1911)

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23
Q

Discovered the Rh blood group

A

Karl Landsteiner, Alex Wiener, Philip Levine, and Rufus Stetson(1939/40)

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24
Q

Created the impellor and gravitator for blood collection and transfusion.

A

James Blundell

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25
Used a complex device in which the donor’s back was lanced multiple times and capillary blood extracted using suction cups
Gesellius
26
In Bellevue hospital (1876)
Aveling device (1876)
27
First to succeed in coming up with an appropriate device for performing transfusion
Edward E. Lindemann
28
Carried out vein-to-vein transfusion of blood by using multiple syringes and a special skin cannula for puncturing the vein through the skin
Edward E. Lindemann
29
Designed syringe-valve apparatus for practical blood transfusion
Unger
30
Recommended the use of sodium phosphate as an anticoagulant for blood transfusion
Braxton Hicks (1869)
31
Reported the use of sodium citrate as an anticoagulant solution for blood transfusion
Albert Hustin (1914)
32
Determined the minimum amount of citrate used for anticoagulation and demonstrated its nontoxicity in small amounts
Richard Lewisohn (1915)
33
Found that citrated blood could be refrigerated for several days before use
Richard Weil (1915)
34
Introduced a citrate-dextrose solution for the preservation of blood
Rous and Turner (1916)
35
First transfusion of stored blood (in Word War I)
Oswald Robertson
36
Introduced the formula for the preservative acid-citrate-dextrose (ACD)
John Loutit and Patrick Mollison (1943)
37
Long-term red cell preservation by freezing Showed that glycerol could prevent freeze-thaw damage
Smith and colleagues (1950)
38
Introduced an improved preservative solution, citrate-phosphate-dextrose (CPD), which was less acidic and eventually replaced ACD as the standard preservative used for blood storage
Gibson (1957)
39
Approved the use of adenine for blood preservation
US Food and Drug Administration (1978)
40
Established the first blood donor service
Percy Oliver (1921)
41
The first true predecessor of the modern blood bank
Mayo clinic (1935)
42
First to coin the phrase “blood bank” for operation because blood could be stored and saved for future use o Blood was collected into glass flasks containing sodium citrate, sealed, and stored in a refrigerator o Pilot tubes were prepared for typing and serology testing
Bernard Fantus
43
Organized a highly successful mobile blood bank that could be transported wherever needed
Federico Duran-Jorda (1936-1939)
44
Transfused plasma to a patient
Joseph Elliot
45
Appointed as the first director of the American Red Cross. His pioneer work during World War II is the development of techniques in blood transfusion and blood preservation, leading to the establishment of a wide system of blood banks
Charles Drew (1941)
46
Father of Modern Blood Bank Head of America's plasma for Britain program First to develop and implement strict procedures for blood collection and testing on a large industrial scale.
Charles Drew (1941)
47
Landmark publication involving the efforts of several countries for blood preservation
Journal of Clinical Investigation (1947)
48
Described a system in which the blood was collected into a collapsible bag of polyvinyl resin o Plastic had the flexibility to permit the removal of plasma following sedimentation or centrifugation
Carl Walter and William Murphy (1952)
49
fractionation method that yielded albumin, fibrinogen, and immunoglobulins Developed the first cell separator - in what yr
Edwin Cohn 1951
50
established the efficacy of albumin
Prof Isodor Ravdin
51
Used centrifugation technology to separate whole blood into plasma and red blood cells to perform the first reported therapeutic plasmapheresis procedure
A. Solomon and J. L. Fahey (1960s)
52
developed the “Latham bowl” and the first apheresis machine was introduced
Alan Latham (1971)
53
used to extract one cellular component, returning the rest of the blood to the donor
Apheresis (1972)
54
the first attempt at crossmatch procedure; major and minor crossmatch began
Weil and Ottenberg (1907)
55
Antibody screen began
1950s
56
AABB made the minor crossmatch unnecessary
1976
57
Abbreviated, or immediate-spin, crossmatch was implemented in the absence of antibodies in the current antibody screen or the patient’s past record
1980s
58
The blood banking community proposed the elimination of in vitro crossmatch under certain defined circumstances, and the adoption of the computer crossmatch
1990s
59
HBsAg
Before 1980
60
HBc ab
1986
61
HCV ab
1990
62
HCV NAT testing
1999 under IND/licensed in 2002
63
HIV 1/2 antibody
HIV-1: 1985; HIV-2: 1992
64
HIV-1 p24 antigen
1996, discontinued 2002
65
HIV-1 NAT testing
1999 under IND/licensed in 2002
66
HTLV-I/II antibody
1997
67
Syphilis
Before 1980
68
Trypanosoma cruzi antibody/Chaga’s disease
2007/currently not mandated
69
West Nile Virus NAT testing
2003 under IND/licensed in 2007
70
published research about a technique to prepare something like an immunosorbent to fix antibodies or antigens to the surface of a container
Wide and Jerker Porath (1966)
71
at Stockholm University invented ELISA
Peter Perlmann and Eva Engvall (1971)
72
Independently published papers for performance of EIA/ELISA
Anton Schuurs and Bauke van Weemen in Netherlands
73
Gel Technology was developed by
Dr. Yves Lapierre
74
Nucleic acid amplification test (NAT) for HIV and hepatitis C virus (HCV) licensed by
FDA (2002)

IH LEC (1 decks)

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