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Immunology and Serology - history > History > Flashcards

History Flashcards

1
Q

worked on serum therapy

A

Emil Adolf von Behring

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2
Q

known for his work on malaria, where he discovered the life cycle of Plasmodium in mosquito.

A

Ronald Ross

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3
Q

founder of modern bacteriology

known for his role in identifying the specific causative agents of tuberculosis, cholera, and anthrax

A

Robert Koch

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4
Q

 discovered pathogenic agent for malaria

A
  1. Charles Louis Alphonse Laveran
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5
Q

 Received the Nobel prize in recognition of his work on vascular suture and the transplantation of blood vessels and organs

A
  1. Alexis Carrel
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6
Q

 Studied, coined and treated “anaphylaxis”

A
  1. Charles Robert Richet
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7
Q

 led to an increased understanding of how the immune system affects the chances of getting cancer

A
  1. Leonell Strong & Clarence Little
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8
Q

 Discovery of Hapten (smallest antigen)

A
  1. Karl Landsteiner
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9
Q

for his discoveries relating to immunity (Complement)

A
  1. JULES BORDET
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10
Q

with Octave Gengou, he isolated Bordetella pertussis in pure culture in 1906 and posited it as the cause of whooping cough.

A
  1. JULES BORDET
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11
Q

For work on cutaneous allergic reactions

A
  1. CARL PRAUSNITZ (AND HEINZ KÜSTNER
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12
Q

Found lysosome

A
  1. ALEXANDER FLEMING
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13
Q

He cured syphilis with malaria therapy.

A
  1. Julius Wagner-Jauregg
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14
Q

the first to test the efficacy of transfusing humans with cadaver blood.

A
  1. Dr. Serge Yudin
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15
Q

He demonstrated that the specific arrangement between antigen, antibody, and complement is accompanied by the manufacture of anaphylatoxin

A
  1. Ernst Friedberger
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16
Q

 Production of the anti-diphtheria serum

A

Pierre Paul Emile Roux

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17
Q

 Discovered the antigen-antibody hypothesis

A

John MArrack

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18
Q

 Quantitative precipitin reaction

A

Michael Heidelberger

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19
Q

the first major histocompatibility complex discovered.

A

histocompatibility-2 (H-2)

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20
Q

 Identification of the H-2 antigen in mice

A

Peter Gorer

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21
Q

the world’s foremost authority on the serology and serological genetics of tissue transplantation.

A

Peter Gorer

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22
Q

 Identification of Rh antigens

A

Karl Landsteiner / Alexander Weiner

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23
Q

 Developed the immunofluorescent technique

A
  1. Albert Coons
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24
Q

 Immunological hypothesis of allograft rejection

A
  1. Peter Medwar
25
Q

 Establish theorems of transplantation immunity

A
  1. Peter Medwar
26
Q

 helped develop a Japanese encephalitis vaccine to protect American troops in the World War II Pacific theater of operations

A
  1. Maurice Hilleman
27
Q

antibody production in relation to the development of plasma cells.

A
  1. Astrid Fagraeus
28
Q

genetically determined structures on the cell surface that regulate immunological reactions

A
  1. George Davis Snell
29
Q

discovered the suppressor T cells

A
  1. Richard Gershon
30
Q

 Published Yellow Fever in 1951

A
  1. Max Theiler
31
Q

 He is also known as “The Father of Modern Vaccines”

A
  1. John Franklin Enders
32
Q

 Discovery in 1937 of antihistamines which block the neurotransmitter histamine and are used

A
  1. Sir Daniel Bovet
33
Q

his discovery relating to synthetic compounds for the blocking of the effects of certain substances occurring in the body, especially in its blood vessels and skeletal muscles

A

Sir Daniel Bovet

34
Q

 Discovery of acquired immunological tolerance.

A
  1. Sir Frank McFarlane
35
Q

discovered that Major Histocompatibility Complex (MHC) is also responsible for antigen recognition of T cells from the infected cells aside from the virus antigen

A
  1. PETER C. DOHERTY and 2. Rolf Martin Zinkernagel
36
Q

demonstrated the relationship between hormones and certain types of cancer

A
  1. CHARLES HUGGINS
37
Q

Discovered a virus that can cause cancer in chickens

A
  1. FRANCIS PEYTON ROUS
38
Q

Interpretation of the genetic code and its function in protein synthesis.

A
  1. Robert W. Holley, Har Gobind Khorana and Marshall w. Nirenberg
39
Q

 Discoveries concerning the replication mechanism and the genetic structure of viruses

A
  1. Max Delbrück, Alfred D. Hershey and Salvador E. Luria
40
Q

 Discovery on the interaction between tumor viruses and the genetic material of the cell

A

David Baltimore and 2. Renato Dulbecco and 1. Howard Martin Temin

41
Q

Hepatitis B virus, and later developed its diagnostic test and vaccine.

A

Baruch Samuel Blumberg

42
Q

Developed radioimmunossay (RIA) techniques; used RIA to analyze peptide hormones in the brain

A

Rosalyn S. Yalow/Roger C.L. Guillemin/ Andrew Schally

43
Q

restriction enzymes and their application to problems of molecular genetics

A

Werner Arber/ Daniel Nathans/ Hamilton Smith

44
Q

biochemistry of recombinant DNA

45
Q

sequencing of DNA

A
  1. Walter Gilbert and Frederick Sanger
46
Q

 discoveries concerning prostaglandins and related biologically active substances

A
  1. Sune K. / John Vane / Bengt Ingemar Samuelsson
47
Q

mobile genetic elements

A
  1. Barbara McClintock
48
Q

PCR

A
  1. Kary Mullis
49
Q

concerning the specificity in development (lymphocyte clonality

A
  1. Niels Jerne
50
Q

production of monoclonal antibodies

A
  1. Cesar Milstein/ Georges Koehler
51
Q

the genetic mechanism that produces antibody diversity

A
  1. Susumu Tonegawa (利根川 進 Tonegawa Susumu)
52
Q

discovery of the cellular origin of retroviral oncogenes.

A
  1. Harold Vermus and J. Micheal Bishop
53
Q

“organ and cell transplantation in the treatment of human disease.”

A
  1. J.E. Murray and E.D. Thomas
54
Q

how the immune system recognizes virus-infected cells uncovered the general mechanisms of the immune system to distinguish foreign agents from its own cells and tissues

A
  1. ROLF M. ZINKERNAGEL and PAUL C. DOHERTY
55
Q

 specificity of the cell mediated immune defense (“dual recognition”).

A
  1. ROLF M. ZINKERNAGEL and PAUL C. DOHERTY
56
Q

 for their discovery of human immunodeficiency virus

A
  1. Françoise Barré-Sinoussi and Luc Montagnier
57
Q

 discoveries concerning the activation of innate immunity

A
  1. B.A. Beutler and J.A. Hoffmann
58
Q

 discovery of the dendritic cell and its role in adaptive immunity

A
  1. R. M. Steinman

Immunology and Serology - history (2 decks)

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