History Flashcards
First time a blood transfusion was recorded in history.
Pope Innocent VII, 1492
How many young men where blood was taken and transfuse to the Pope?
3
Found the first example of blood preservation research. What is the first anticoagulant suggested for use in blood transfusion.
Braxton Hicks, 1869
Sodium phosphate
Discovery of ABO Blood Groups
Karl Landsteiner, 1901
Vein to vein transfusion.
Edward E. Lindeman
Designed his syringe valve apparatus.
Unger
Discovered the sodium citrate as an anticoagulant. He has observed that patients that time suffer from
citrate toxicity.
Hustin, 1914
Causes hypocalcemia and hypomagnesemia
Citrate toxicity
Two electrolytes that citrate chelates
Calcium and magnesium
He propose minimum of citrate needed for anticoagulation. Development of preservative solutions to enhance
the metabolism of the RBC.
Lewisohn, 1915
Introduced a citrate-dextrose solution for the preservation of blood.
Rous and Turner
He develop techniques in blood transfusion and blood preservation.
Dr. Charles Drew
Founder of Red Cross and Red Crescent
Dr. Charles Drew
When was Dr. Drew was appointed as the First American Red Cross blood bank at the Presbyterian Hospital.
Febuary 1941
Introduced the formula for the preservative acid-citrate dextrose (ACD).
Loutit and Mollison, 1943
Use in apheresis or hemapheresis where you will just get the particular component like platelets.
acid-citrate dextrose (ACD)
The Journal of Clinical Investigation was published.
July 1947
This journal contains dozens of papers to blood preservation or basically a compiled researches regarding blood preservations.
The Journal of Clinical Investigation
Introduced an improved preservative solution called CPD.
Gibson, 1957
Not only the whole blood is what can be transfused to the patient, it can also be packed red blood cells, plasma only, or platelets only, or granulocytes only depending on the need of the patient.
Component Therapy
Problem arise due to frequent transfusion and the massive use of blood
circulatory overload
