Histories Flashcards

1
Q

IHD

A

Risk factors:
- Previous IHD, CTCA, Ca score
- Metabolic: hyperlipidaemia, HTN, obesity, exercise, DM
- FHx
- Smoking and details
- Premature menopause, OCP
- Chronic inflammatory disease, long term use of COX2i and NSAIDs
- High serum homocysteine levels
- Erectile dysfunction
And make sure to ask about successful management of risk factors

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2
Q

IE

A

Presenting Sx
Sx of emboli
Antibiotic allergies

Risk factors:

  • Recent dental, endoscopic or operative procedures
  • Rheumatic fever
  • Other heart disease, heart operations
  • IVDU
  • Previous abx use
  • Congenital heart disease
  • Immune suppression
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3
Q

CCF

A

Sx of heart failure

  • Orthopnoea
  • PND
  • Reduced ET and quantification
  • Change in weight

MUST include NYHA

Risk factors:

  • Arryhthmias
  • Discontinuation of medications
  • MI
  • Anaemia
  • Infection/fever
  • Thyrotoxicosis
  • Surgery
  • PE
  • High salt intake, meds that can cause salt/water retention
  • Pregnancy
  • FHx, haemochromatosis
  • Other Coronary risk factors (see IHD)

Ix - make sure to to ask re TTE and LVEF

Cx - arrhythmias

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4
Q

HTN

A

Risk factors:

  • T2DM
  • FHx of premature stroke/CVD
  • Smoking
  • ETOH
  • Obesity
  • High salt intake
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5
Q

Cardiac transplant

A
Cause of cardiac failure
?cardiac investigations - LHC, TTE
Symptoms prior to surgery
Treatment prior to surgery
How long since transpant, complications post op
Rejection, biopsies (weekly first 3/52, then 2wkly for months, then 6/12ly)
Admissions since
Drugs, immunosuppressants, complications of medications
Understanding re rejection
Impact on life and QoL
Control of other risk factors
Risk of cancer, skin cancer, HTN
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6
Q

Arrhythmias

A

Symptoms, SOB
Syncope, freq, duration etc.
HF symptoms

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7
Q

CKD

A

Risk factors:

  • Infections - HIV, HCV, HBV
  • AI conditions
  • CTD disease
  • Drugs
  • HTN
  • DM
  • Recent infections
  • FHx
  • Malignancies
  • Occupational exposures

Symptoms

  • Nocturia
  • Lethargy, anorexia
  • Fluid retention, weight, dry weight
  • Pruritis
  • Uricaemia: CP, pericarditis, confusion, GIB, neuropathy
  • Serositis

Precipitants:

  • NSAIDs
  • abx - trimethoprim, aminoglycosides
  • Contrast
  • Infection
  • ACEi, ARB
  • Dehydraiton
  • Anaemia

Complications:

  • MBD
  • Anaemia
  • HTN
  • Gout
  • HF, fluid overload
  • Peripheral neuropathy
  • Altered cognition
  • Nutrition
  • Mental health

Risk factors for progression

  • Low birth weight
  • HTN
  • AKI
  • Proteinuria
  • Smoking
  • Hyperuricaemia
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8
Q

Dialysis

A

Access

  • Fistula - when, how many, which side, USS
  • Permacath - when, where, how many
  • Vascath

HDx versus PD
Where dialysis happens
Regime

Side effects

  • HTN
  • Hypotension
  • Adjustment of medications
  • Issues with access
  • Pain
  • Bleeding
  • Infections

Transplant work-up
Social arrangement

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9
Q

Renal Transplant

A

Work up

  • Cause of ESRF
  • Management of ESRF
  • How long on list?

Contraindications

  • Recent malignancy
  • Frailty
  • Untreatable infection
  • Untreatable, severe IHD
  • Active vasculitis, anti-GBM
Previous transplant
- How many, kind of transplant
- Post op complications and course
- Improvement in Sx, QoL
Immunosuppression
- Which drugs
- Complications - HTN, DM, hair loss
Rejection episodes
- Symptoms
- How managed
- Signs to be aware of
Infection, CMV status
Thrombosis
Graft failure
Recurrence of disease
Malignancy
- Monitoring
- Biopsies, USS
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10
Q

Bronchiectasis

A
- Symptoms:
Haemoptysis
SOB, wheeze
Chronic sinusitis
CP
LoW, fever, anorexia
RHF (late event)

Risk factors:

  • Childhood whooping cough/measles
  • History of recurrent LRTI
  • Immunocompromise, HIV, AI conditions
  • Immunisation history
  • Smoking
  • COPD, airway disease
  • ABPA

Investigations

  • CXR, CT chest
  • Sputum mcs, history of bugs
  • Immunoglobulins, immune function
  • Testing for CF
  • Eosinophils

Management

  • ?Prophylaxis
  • Abx
  • Pulm rehab, clearance methods
  • Vaccinations
  • Home O2
  • Surgery? (uncommon)

Complications

  • Precipitating causes
  • History of hospital admissions, history of abx courses

How it impacts life

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11
Q

Lung Cancer

A

How and when diagnosed

  • Symptoms: LoW, fatigue, fever, night sweats, cough, haemoptysis, Sx of paraneoplastic/mets
  • Scans at time

Risk factors:

  • Smoking
  • COPD, b/g airway disease
  • Immunosuppression, CT
  • Systemic conditions
  • Genetics, FHx
  • Occupational exposures - asbestos, mining, uranium
  • Chronic scarring, TB, scleroderma, ILD

Ix:

  • CXR, CT
  • Bronchoscopy
  • Bx
  • PET scan

Management

  • CT, RT
  • Surgery
  • Follow up

Complications

  • CT and RT
  • Post op Cx
  • Mets
  • Paraneoplastic
  • SVC obstruction

Trajectory
Follow up, monitoring scans

Impact on QoL, SOB, independence

Prognosis, GoC
Pall care involvement

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12
Q

COPD

A

Risk factors:

  • Smoking
  • Workplace exposures, wood, charcoal, coal smoke, dust
  • Plastic, textile and rubber manufacturing
  • Leather and food industry

Ix:

  • PFT
  • CXR, CT chest
  • Blood gases
  • ECG
  • Echo
  • Alpha-1-antitrypsin

Management

  • Inhalers, steroids
  • CPAP, BiPAP
  • Smoking cessation
  • Abx prophylaxis
  • Vaccinations
  • Home O2
  • Management of pulmonary HTN
  • Lung transplant

Complications

  • Infections
  • PTX, chest drains
  • Cx of inhalers
  • Hospital admissions, ICU admissions
  • Cardiac
  • Pulmonary HTN

Trajectory
Prognosis

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13
Q

Sleep apnoea

A

Symptoms: daytime somnolescence, snoring, fatigue, unexplained resp failure

Risk factors

  • Obesity
  • ETOH
  • Meds
  • Tonsillar enlargement
  • COPD
  • Hypothyroidism

Ix

  • Sleep study
  • PFTs
  • Epworth sleepiness scale
  • Echo

Management

  • Sleep hygiene
  • Weight loss
  • Surgery
  • CPAP

Complications

  • Pulmonary HTN
  • HTN
  • CVD, CCF
  • Restless legs

Trajectory
Adherence

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14
Q

ILD

A

Symptoms: SOB, Low, fevers, fatigue, reduced ET
Duration

Risk factors:

  • Smoking
  • Occupational exposures
  • Pets
  • FHx
  • CTD, AI conditions
  • Meds: bleomycin, MTX, Amiodarone
  • TB, chronic infections
  • Pre-existing asthma
  • RT

Investigations:

  • CXR, HRCT
  • PFT
  • ABG
  • Blood film
  • TTE
  • Biopsy

Management

  • Depends on exposure
  • Smoking cessation
  • Antifibrotics (perfenidone)
  • Steroids
  • Home O2
  • Abx
  • Immunosuppressants
  • Lung transplant

Complications

  • Respiratory arrest
  • Infections, hospital admissions
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15
Q

Pulmonary HTN

A
Risk factors:
- FHx
- CTD
- COPD
- ILD
- Smoking
- HF, LH disease
- Drugs, CT
- HIV
- TB
- OSA, OHS
- Arteritis
Try to classify based on type of PHTN I guess

Ix

  • TTE
  • HRCT/CT chest
  • R heart cath
  • ECG
  • Blood gas

Management

  • Manage underlying condition
  • Prostacyclins
  • Sildenafil
  • Endothelin antagonists
  • Home O2
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16
Q

Sarcoidosis

A

Risk factors

  • FHx
  • Other AI conditions
  • Viral infections, triggers

Investigations

  • CXR, HRCT
  • ESR
  • ACE level (nonspecific)
  • Ca levels

Management

  • PNL
  • Other immunosuppressnts

Complications

  • Cutaneous: erythema nodosum, plaques, maculopapular, subcut nodules, migratory polyarthralgia
  • Lofgren
  • Eye: blurred vision, excess tears, uveitis, sicca
  • Nasal congestion
  • Renal disease
  • Neuro: faocial nerve palsy
  • Arthralgia
  • Cardiac: heart block, arrhythmias, PPM, ICD
  • Pregnancies: complications
  • GIT, liver
17
Q

CF

A

Risk factors

  • FHx
  • Other AI conditions

Investigations

  • Infancy - sweat test, DNA markers
  • CXR
  • CT chests

Management

  • CFTR inducers and potentiators
  • Abx courses, prophylaxis
  • Pulmonary rehab
  • Lung transplant
  • Vaccinations

Complications

  • Infections
  • Bronchiectasis
  • Pulmonary HTN
  • HF
  • Mental health
  • DM
  • Fertility/sexual fx
  • GIT
  • Nasal polyps, sinusitis

Trajectory
?work up for transplant
Adherence to therapy
Pt’s coping

Prognosis

18
Q

TB

A

Risk factors

  • Ethnicity/place of birth
  • Overseas travel
  • Immunosuppression/compromise

Ix

  • Mantoux, QFG
  • CXR, CT chest
  • Sputum AFB, TB PCR
  • Resistance testing
  • HIV, HBV, HCV
  • Bronch, biopsies

Management

  • RIPE treatment
  • Family tracing, contact tracing
18
Q

Lung Transplant

A

Why in hospital?

Cause of lung failure
Initial Sx
Risk factors
Contraindications, relative contraindications

Investigations

  • TTE
  • Heart cath
  • PFTs
  • Blood gases
  • CXR, CT imaging, PET scans

Management

  • One side? Both
  • Immunosuppression regimen
  • Subsequent imaging, biopsy
  • Post-op care

Complcations

  • Post-op, bleeding
  • Thrombosis
  • Infection
  • Rejection
  • Immunosuppressants
  • CVD, HF
  • Mental health
  • Disease recurrence
19
Q

IBS

A

Symptoms:

  • Pain
  • Diarrhoea/constipation
  • Bloating
  • ABSENCE of red flags/alarm symptoms: Onset >50yo, anaemia, Fe def, weight loss, rectal bleeding, FHx IBD, FHx coeliac, nocturnal symptoms
  • Nil structural cause found

Risk factors

  • History of gastro
  • FHx of IBS
  • Food intolerances
  • PHx physical or sexual abuse
  • PHx somatisation
20
Q

Ulcers

A

Risk factors:

  • DM
  • Thyroid dysfunction
  • Hyperparathyroidism
  • CTD
  • PHx ulcers, gastric surgery
  • Meds, NSAIDs
  • FHx endocrine disorders, MEN1
  • Anticoagulation

Investigations: scope, imaging, biopsies

21
Q

Malabsorption, diarrhoea

A

Presenting symptoms

  • Steatorrhoea
  • LoW
  • weakness
  • anaemia
  • bone pain
  • glossitis, angular stomatitis
  • Bruising
  • Oedema
  • Peripheral neuropathy
  • Rashes
  • Amenorrhoea
  • Cognitive impairment

Aetiology

  • Gastrectomy
  • Liver disease
  • Drugs: ETOH, neomyucin, cholestyramine, isoniazid, PPIs
  • IBD
  • Previous RT
  • Coeliac disease
  • DM
  • HIV

Investigations:

  • AXR, CTAP
  • stool mcs, PCR
  • ?Whipples disease
  • Bloods
  • Vitamin deficiencies
  • Scopes, biopsies
22
Q

IBD

A

Symptoms

  • Diarrhoea, blood
  • Chronology of symptoms
  • Disease activity
  • Fever, malaise, LoW
  • Obstruction

Risk factors

  • FHx
  • Other AI conditions
  • PHx cancer
  • Smoking, ETOH

Investigations

  • CTAP, AXR
  • Bloods, antibodies
  • Scopes, biopsies
  • Genetic testing, NOD2
  • Faecal calprotectin
  • Cancer screening

Complications
- UC
> Intestinal: toxic megacolon, perforation, haemorrhage, strictures, CRC
> Extra-intestinal: ulcers, pyoderma gangrenosum, erythema nodosum, uveitis, conjunctivitis, episcleritis, NAFLD, PSC, cirrhosis, cholangiocarcinoma, amyloid, anaemia, VTE, arthropathy, ank spon
- CD
> Intestinal: anal disease, fistulas, fissures, abscesses, obstruction, toxic megacolon, CRC
> Extra-intestinal: ulcers, pyoderma gangrenosum, erythema nodosum, sweet syndrome, uveitis, conjunctivitis, episcleritis, stones, renal disease, malabsorption, osteomalacia

23
Q

CRC

A

Symptoms

  • LOW, anorexia, fever, night sweats
  • Change in bowel motions
  • Mets
  • IBD
  • Nerve pain

Risk factors

  • FHx, FAP, Lynch, MUTYH
  • IBD
  • Smoking
  • Polyps
  • Other cancers
  • PHx infections, SA, polymicrobial growths
  • DM
  • Immunosuppression/compromsie

Investigations

  • Imaging
  • Genetic testing
  • Scopes, biopsies
  • PET
  • Cancer screening
24
Q

CLD

A

Symptoms

  • Jaundice, pruritis
  • Confusion, hepatic encephalopathy
  • Change in bowel motions
  • Anaemia
  • Symptoms from portal HTN

Risk factor

  • ETOH
  • Viral infections: HIV, HBV, HCV
  • NAFLD, obesity, metabolic syndrome
  • IBD
  • DM, CCF, arthropathy
  • Haemochromatosis
  • Wilson’s disease
  • IVDU
  • AIH

Investigations

  • USS, fibroscan
  • Viral testing
  • Biopsy
  • LFTs, FBE

Management

  • Treatment of underlying cause
  • Diet advice
  • Banding
  • BB
  • Prophylaxis
  • Cancer screening
  • Vaccinations
  • Transplant work-up

Complications

  • Malnutrition
  • Portal HTN - varices, bleeding, ascites, SBP
  • Bleeding
  • CVD
  • HCC
  • Hepatorenal
  • Hepatocardiac
  • MBD
  • Complications of medications
  • Cryoglobulins
25
Q

Liver transplant

A

Symptoms

  • Initial cause of liver failure
  • Duration of disease
  • Timing of transplant

Contraindications

  • Active infection
  • Active/untreatable malignancy
  • Severe/untreatable CVD
  • CholangioCa
  • Ongoing ETOH
  • Onoging IVDU and non-compliance
  • AIDS
  • diffuse portal bein thrombosis, advanced hepatorenal/cardiac disease
  • Poor social support
  • Frailty

Investigations

  • TTE
  • Viruses, infections
  • Ca screening
  • ?heart cath
  • PFTs

Management

  • When was transplant
  • How many
  • Types of transplant
  • How long did they last
  • Immunosuppression

Complications

  • Immunosuppressants
  • Acute thrombosis
  • Infection
  • Rejection
  • CVD
  • Bleeding
  • Graft failure
  • CKD
  • DM
  • Recurrent disease
  • MBD
  • Nutrition
  • De novo cancer