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Oxygen Physio > Historic Discoveries Exam 2 > Flashcards

Historic Discoveries Exam 2 Flashcards

1
Q

pericyte function, regulation of SkM, diffusion, krogh cylinder

A

August Krogh

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2
Q

first discovered the BBB

A

Ehrlich

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3
Q

stained the brain via spinal fluid

A

Goldman

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4
Q

proposed the “hematoencephalic barrier”

A

Lewandowsky

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5
Q

mean transit time (MTT) equation

A

Stewart

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6
Q

discovered AQPs

A

Agre

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7
Q

discovered gas channels

A

Boron

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8
Q

related Co2 to climate change, Q10, equation with activation energy

A

Arrhenius

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9
Q

warm blooded animals in cold climates are larger in body size than relatives in warm climates

A

Bergmann

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10
Q

scaling

A

Schmidt-Nielsen

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11
Q

larger animals live longer than smaller

A

Aristotle

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12
Q

symmorphosis

A

Weibel

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13
Q

“bioblasts”

A

Altman

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14
Q

coined “mitochondria”

A

Benda

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15
Q

stained mito with Janus B redox dye

A

Michaelis

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16
Q

suggested mito as the site of respiration

A

Kingsbury

17
Q

confirmed mito as the site of respiration

A

Kennedy and Lehninger

18
Q

endosymbiotic theory

A

Sagan

19
Q

genome complexity - euks have very high gene power (resulting in more proteins)

A

Nick Lane

20
Q

color of blood in artery (bright red) vs vein (dark red), homeostasis

A

Claude Bernard

21
Q

respiration occurs in the tissues

A

Pfluger

22
Q

absorption of O2Hb

absorption of deO2Hb

A

Seyler (O2Hb)

Strokes (deO2Hb)

23
Q

“histohaematin”

A

MacMunn

24
Q

“radiospectroscope”

A

Lubbers and Niesel

25
Q

chemiosmosis (ATP synthesis) is a “primary energy conserving event”

A

Peter Mitchell

26
Q

CytC aa3 reflectance spectrum, NIRs methods

A

Vandervliet

27
Q 
discovery of cytochrome oxidase 
3 cytochromes (a, b, c)
A

David Kaelin

28
Q

increased O2 = increased glycolysis

action spectra, “atmungsferment”

A

Otto Warburg

29
Q

5 states of mito respiration

A

Britton Chance

30
Q

just sufficient O2

A

LaManna

31
Q

mito defects implicated in lots of diseases (African mtDNA are most diverse)

A

Douglas Wallace

Oxygen Physio (2 decks)

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