Histopath

Question 1

codmans triangle

Answer 1

osteosarcoma

Question 2

t(11:22)

Answer 2

ewings sarcoma

Question 3

cotton wool calcification

Answer 3

enchondroma

Question 4

soap bubble appearance

Answer 4

giant cell

Question 5

CD99+

Answer 5

ewings sarcoma

Question 6

shepherds crook deformity

Answer 6

fibrous dysplasia

Question 7

chinese letters

Answer 7

misshapen bone trabeculae - fibrous dysplasia

Question 8

onion skinning of periosteum

Answer 8

ewings sarcoma

Question 9

malignant bone tumour >40 years

Answer 9

chondrosarcoma

Question 10

sunburst appearance

Answer 10

osteosarcoma

Question 11

brown tumour

Answer 11

hyperparathyroidism (osteitis fibrosa cystica)

Question 12

loosers zones

Answer 12

pseudo fractures = osteomalacia

Question 13

radiolucency with sclerotic rim on xray

Answer 13

osteoid osteoma

Question 14

Olloers syndrome

Answer 14

multiple endrochondromas

Question 15

maffuci’s syndrome

Answer 15

multiple endrochondromas + haemangiomas

Question 16

tumour in hands/feet

Answer 16

endrochondrome - pain and swelling

benign tumours of CARTILAGE

Question 17

(McCune-)Albright syndrome

Answer 17

Fibrous dysplasia (bone replaced by fibrous tissue) 
\+
endocrine symptoms: cafe au lair spots, precocious puberty etc

Question 18

cartilage capped boney outgrowth from bone

Answer 18

osteochondroma

most common benign bone tumour

Question 19

type of bone responsible for calcium metabolism

Answer 19

cancellous

Question 20

pathological/immature bone

Answer 20

woven

Question 21

type of bone responsible for support and protection

Answer 21

cortical (80%)

Question 22

cradle cap

Answer 22

seborrhoeic dermatitis (yellow scales = yeast)

Question 23

Auspitz sign

Answer 23

pin point bleeding - psoriasis

Question 24

test tubes in a rack

Answer 24

clubbing of tete ridges = psoriasis

Question 25

saw toothing of tete ridges

Answer 25

lichen planus

Question 26

lacy appearance of mucous membranes

Answer 26

lichen planus

Question 27

erythema multiforme

Answer 27

annular target lesions - hands and feet Causes: infection (HSV, mycoplasma, fungi) drugs (penicillin, salicylates, anti-malarials, phenytoin)

Question 28

nikolsky (-)

Answer 28

pemphigoid

Question 29

nikolsky (+)

Answer 29

pemphigus

Question 30

sandpaper like scaly lesions

Answer 30

actinic keratosis

Question 31

bowens disease

Answer 31

flat red scaly patches = squamous cell carcinoma in situ

Question 32

dome shaped nodule, necrotic crusted centre, clears spontaneously after a few weeks

Answer 32

keratoacanthoma

Question 33

rodent ulcer

Answer 33

BCC

Question 34

salmon pink rash

Answer 34

pityriasis rosea

Question 35

rash in christmas tree distribution

Answer 35

pityriasis rosea

Question 36

fifth disease

Answer 36

parvovirus b19 = slapped cheek syndrome

Question 37

sixth disease

Answer 37

roseola infantum aka exanthema subitum = HHV-6

Question 38

kawasaki

Answer 38

``` red mouth eyes LN heart rash on hands and feet 5 days ```

Question 39

buergers

Answer 39

smoking corkscrew appearance on angiogram ulceration of feet and fingers

Question 40

gottron papules

Answer 40

violet scaley plaques over hand joints - polymyositis + dermatomyositis

Question 41

anti-Jo1

Answer 41

polymyositis + dermatomyositis

Question 42

LE bodies

Answer 42

SLE

Question 43

HLA DR3

Answer 43

SLE

Question 44

HLA DR5 +DRw8

Answer 44

limited/diffuse scleroderma

Question 45

churg straus

Answer 45

pANCA asthma eosinophilia

Question 46

haemodialysis ass amyloidosis

Answer 46

deposition of beta 2 microglobulin

Question 47

secondary amyloidosis

Answer 47

AA amyloidosis | secondary to chronic infections/inflammation

Question 48

primary amyloidosis

Answer 48

AL amyloidosis | ass with multiple myeloma/plasma cell dyscrasias