Histopath Flashcards

1
Q

70 year old gp tight chest pain radiates left arm , relieved by rest , her ecg revealed some st depression

A

Stable Angina

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2
Q

50 year old smoker
Hun
Continuous crushing central chest pain
Radiate left arm
Ecg st elevated

A

Acute MI

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3
Q

63 year old obese
Diabetic male
Presents a and e tight chest pain
Radiate left arm
Lasted less than 20 mins
CK wasn’t raised

A

Acute CS

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4
Q

68 year old man presents with sudden onset chest pain
Radiated to back
Patient was shocked
Hemiplegia and chest X-ray shows mediastinal enlargement

A

Aortic dissection

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5
Q

73 year known hx of peripheral vascular disease
A and e
Sudden onset hemiplegia resolved within 24 hours

A

TIA

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6
Q

What is decubitus angina?

A

When patient lays down
Complication of cardiac failure
Strain on heart

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7
Q

Acute MI , pansystolic murmur on auscultation

A

Myomalacia cordis

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8
Q

28 year old sportsman a and e
Severe chest pain and breathlessness
He has a hx of asthma
Systolic murmur

A

Hypertrophic cardiomyopathy

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9
Q

Sharp retrosetanl pain
Worst on inspiration

A

Pericarditis

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10
Q

Middle aged lady
Faint at gym
Systolic ejection murmur

A

Aortic stenosis

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11
Q

A & E our of breathe
Severe chest pain
Mid systolic click late systolic murmur

A

Myxomatous mitral valve

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12
Q

Young boy
Skin rash
Joint pain in elbow and knee
Ejection systolic murmur
Friction rub

A

Acute rheumatic fever

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13
Q

Woman
Sudden onset fever and malaise
No prev hx or heart disease
Auscultation= heart murmur
Sepsis

A

Acute bacterial endocarditis

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14
Q

40 year old man
Sharp chest pain
Percardial friction rub
Diminished heart sounds
Raised JVP

A

Pericarditis

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15
Q

25 year old
Palpitation
Chest x ray enlarged heart
Echo thickened septum

A

Hypertrophic cardiomyopathy

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16
Q

4 MI
Shortness of breath and ankle swelling
Enlarged liver
Echo shows dilated heart

A

Cardiac failure

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17
Q

Bronchiectasis
Inhaled tobramycin
Pseudomonal infection
Delta F508 mutation

A

Cystic fibrosis

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18
Q

Smoker
Jaundice
Abdo pain
Scratch marks
He has lost 5kg in 2 months
Dilated intrehepatic bile ducts

A

Carcinoma of head of pancreas

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19
Q

Severe diarrhoea
Hypokalaemia
Metabolic acidosis
RUQ mass
Stool bicarbonate high , urine anion gap negative

A

VIPoma - Werner Morrison syndrome

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20
Q

Back pain
Lose appetite
Dropping dress sizes
She recently diabetes
Large central mass ,
hepatosplenomegaly

A

Carcinoma tail of pancreas

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21
Q

Worsening abdo pain
Poor diet
And weight loss
Thiamine

A

Chronic alcohol pancreatitis

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22
Q

65 year old female
Large cystic mass on tail of pancreas
Further cytology
Reported presence of epithelium

A

Cystadenoma

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23
Q

55 year old
Diabetic
Afro Caribbean
Weight loss
Poor diet
Gnawing pain on his back
Felt under the chest

A

Carcinoma of pancreas

24
Q

Inflammatory condition
Exocrine pancreas
Injury to acinar cells

A

Pancreatitis

25
Q

ERCP finding incomplete fusing of pancreatic divisum

A

Pancreas divisum

26
Q

Pancreatic pseudo cyst and cystadenoma

A

Pancreatic pseudo cyst - Well defined capsule - fibrous and granulation tissue / combo of both

Cystadenoma - doesn’t possess an epithelial lining - contains a fluid collection

27
Q

Barrett oesophagus

A

Squamous turn to Columnar
GOR
Ulcer
Undergoing malignant change

28
Q

Causes of action acid and pepsin
Duodenal mucosa
Increased output of stomach acid
Include pain upper abdo
Esp when stomach is empty

A

Duodenal ulcer

29
Q

Failure to produce IF
Reduction in absorption of b12 fr the bowel
Presence megaloblasr in bone marrow

A

Pernicious anaemia

30
Q

Dilated veins
Lowe oesophagus
Portal hypertension
Rupture life threatening haematemesis
Bleeding stopped compression balloon
Scleropathy
Applying elastic bands via endoscope

A

Oesophageal varices

31
Q

Spiral flagellated gram neg bacteria
Found stomach within mucosal layer
Occurs majority of Middle Aged people
Progressive gastritis
Duodenal and gastric ulceration

A

H pylori

32
Q

Breach in mucosa extends muscularis mucosa into submucosa and deeper

A

Peptic ulcer

33
Q

Present in almost all patients duodenal ulcer and 70 gastric ulcer

A

H pylori

34
Q

Duodenal ulcer and 70% gastric ulcer

A

H pylori infection

35
Q

10% primary lymphoma
HLA b8

A

Coeliac disease

36
Q

Commonest cause of oesophagitis

A

GORD

37
Q

Re epithelialisarjon by metaplatic columnar epithelium by goblet cells

A

Barrett’s oesophagus

38
Q

40 year old male
Long hx of burning epigastric pain
Worse on lying flat
Endoscopy reveals squamous lining and increases basal cell proliferation

A

GORD

39
Q

38 year old rheumatoid arthritis
Single ep of malaena
Neutrophilic infiltrate

A

Acute gastritis

40
Q

Diarrhoea
Weight loss
Biopsy of duodenum
Intraepithelial cytotoxic T cells

A

Coeliac disease

41
Q

Duodenal ulcer

A

Epigastrc pain
Relieved by antacids and meals
pos CLO test

42
Q

Epigastric pain
Endoscopy. Reveals 3.2cm columnar metaplasia
In lower oesophagus
Goblet cells are seen

A

Barrett oesophagus

43
Q

Epigastric pain
Dyspepsia
Pain gets worse at night when he is hungry
Nausea and flatulence NSAIDS

A

Duodenal ulcer

44
Q

Low retrosternal dysphagia
Initial to solids now also to liquids
Chest pain and WL over last 3 months
Social hx reveals she has been a heavy smoker
Drinks around 20 units of alcohol a week

A

Carcinoma of oesophagus

45
Q

Watery diarrhoea
Abdo cramps
Nausea
Vomit
Low grade fever
3 days after BBQ

A

Cryptosoporidiosis

46
Q

Zolinger Elinson syndrome

A

Haematemesis
Diarrhoea
Recurrent peptic ulceration
Persistently high serum gastrin levels
Large 3cm actively bleeding ulcer

47
Q

Chest pain
Regurgitation post solids and liquids
Occur after swallowing
Beak like tapering
Failure of relaxation of LOS

A

Achalasia

48
Q

3 month hx
Anorexia , wl , epigastric pain
Iron def anaemia
Leather bottle stomach
Signet ring

A

Adenocarcinoma

49
Q

Severe headache
Scalp tenderness
Esr and crP raised
Giant cells

A

Temporal arteritis

50
Q

Hep B
Weight loss
Muscle aches
Abdo pain
High bp
Blood and protein

A

Polyarteritis nodosa

51
Q

Treatment renal failure
Tingling wrist and hands

A

Haemodilayiss relayed amyloidosis

52
Q

Peripheral oedema
Hepatosplenomgealy
Bone Erosion
High levels kappa uniform lights chain

A

Myeloma associated amyloidosis

53
Q

Hodgkin

A

Painless enlarged lymph node
Hepatosplenomaly
No night sweats
Weight loss
Fever
Raise esr
Abnormal liver biochemistry

54
Q

Chronic rheumatology is disease
Abdo discomfort
Pos Congo red stain

A

Reactive amyloidosis

55
Q

Abdo discomfort
Fresh blood rectum
No palpable mass
Outpovhing though muscular layer

A

Diverticula’s disease

56
Q

Rectal bleed
Bright red
Constipated
Polyps in colon
Lost lots weight
Mass n right lumbar region - non tender

A

Colon cancer

57
Q

Crohns
T

A

Terminal ileum
Transmural inflammation with granulomas