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midterm exam > Histopath > Flashcards

Histopath Flashcards

1
Q

Hypertension and aortic valve disease can lead to which type of cellular adaptation?

A. Pathologic hypertrophy
B. Physiologic hyperplasia
C. Pathologic hyperplasia
D. Physiologic hyperplasia

A

A. Pathologic hypertrophy

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2
Q

Imperforate anus is an example of which of the following abnormalities in cell growth

A. Agenesia
B. Aplasia
C. Hypoplasia
D. Atresia

A

D. Atresia

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3
Q

Type of pathoogic atrophy that may develop secondary to pressure atrophy

A. Atrophy of disuse
B. Vascular atrophy
C. Endocrine atrophy
D. Exhaustion atrophy

A

B. Vascular atrophy

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4
Q

Secondary change in somatic death important in establishing time of death

A. putrefaction
B. algor mortis
C. rigor mortis
D. livor mortis

A

B. algor mortis

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5
Q

Removing part of liver can lead to:

A. Compensatory hypoplasia
B. Compensatory hypertrophy
C. Aplasia
D. None

A

B. Compensatory hypertrophy

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6
Q

Also referred as “atypical metaplasia”

A. Anaplasia
B. Dysplasia
C. Metaplasia
D. None of these

A

B. Dysplasia

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7
Q

Affected cells may appear as ghostly

A. Caseous necrosis
B. Liquefactive necrosis
C. Coagulative necrosis
D. Fibrinoid necrosis

A

C. Coagulative necrosis

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8
Q

Brain infarct is an example of which of the following types of necrosis?

A. Caseous necrosis
B. Liquefactive necrosis
C. Coagulative necrosis
D. Fibrinoid necrosis

A

B. Liquefactive necrosis

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9
Q

Autopsy technique that involves ‘en bloc” removal of organs

A. R. Virchow
B. A. Ghon
C. K. Rokitansky
D. M. Letulle

A

B. A. Ghon

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10
Q

Most common antibody label in IHC

A. colloidal gold
B. fluorescein isothiocyanate
C. radiolabel
D. horseradish peroxidase

A

D. horseradish peroxidase

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11
Q

Secondary change in somatic death that occurs 2-3hrs after death

A. livor mortis
B. rigor mortis
C. algor mortis
D. autolysis

A

B. rigor mortis

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12
Q

Necrosis type in TB and lymphoid granuloma

A. Caseous necrosis
B. Liquefactive necrosis
C. Coagulative necrosis
D. Fibrinoid necrosis

A

A. Caseous necrosis

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13
Q

Cellular infiltrate in acute inflammation

A. Neutrophils
B. Plasma cells
C. Macrophage
D. Lymphocytes

A

A. Neutrophils

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14
Q

Microscopic changes in reversible injury

  1. karyorrhexis
  2. fatty change
  3. pyknosis
  4. cellular swelling

A. 1 and 3
B. 1 and 4
C. 2 and 4
D. 2 and 3

A

A. 1 and 3

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15
Q

True of necrosis except

A. death of single cells in cluster of cells
B. cell swelling
C. inflammation in neighboring tissues
D. cellular contents leak out

A

A. death of single cells in cluster of cells

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16
Q

Cell adaptation mechanism characterized by adult-to-adult cell transformation

A. metaplasia
B. dysplasia
C. neoplasia
D. anaplasia

A

A. metaplasia

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17
Q

Change in cell shape, size, and orientation characterize which of the following cellular adaptation mechanisms?

A. Metaplasia
B. Dysplasia
C. Neoplasia
D. Anaplasia

A

B. Dysplasia

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18
Q

Type of necrosis seen in acute pancreatitis

A. Caseous necrosis
B. Liquefactive necrosis
C. Coagulative necrosis
D. Fibrinoid necrosis

A

E. none?

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19
Q

In IHC, use of chromogen diaminobenzidine will result in which of the following end color?

A. Brick red
B. Brown
C. Pink
D. Black

A

B. Brown

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20
Q

Observation of 50-75% differentiated and 25% undifferentiated cells may be reported as ____ in the Broder’s classification

A. Grade I
B. Grade II
C. Grade III
D. Grade IV

A

B. Grade II

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21
Q

Decrease in thymus size during puberty may be classified as what type of cellular adaptation

A. physiologic hyperplasia
B. hypoplasia
C. physiologic atrophy
D. agenesia

A

C. physiologic atrophy

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22
Q

Complete non-appearance of an organ

A. physiologic hyperplasia
B. hypoplasia
C. physiologic atrophy
D. agenesia

A

D. agenesia

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23
Q

Autopsy technique that involves “in-situ” dissection of organs

A. R. Virchow
B. A. Ghon
C. K. Rokitansky
D. M. Letulle

A

C. K. Rokitansky

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24
Q

Organs are removed en-masses is done in which of the ff autopsy techniques

A. R. Virchow
B. A. Ghon
C. K. Rokitansky
D. M. Letulle

A

D. M. Letulle

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25
Q

Developmental defect wherein affected organ shows no resemblance to normal mature structure

A. agenesia
B. aplasia
C. atresia
D. hypoplasia
E. NONE

A

B. aplasia

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26
Q

Apoptosis is characterized by all of the following except:

A. intact cell outline
B. inflammation
C. cell shrinkage
D. none of these

A

B

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27
Q

Purplish discoloration of skin in somatic cell death

A. putrefaction
B. algor mortis
C. rigor mortis
D. livor mortis

A

D. livor mortis

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28
Q

Which may be considered to establish time of patient’s death?

A. putrefaction
B. algor mortis
C. rigor mortis
D. livor mortis

A

B

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29
Q

Solid organs like spleen and kidney may undergo which kind of necrosis most especially when the action of hydrolytic enzymes is blocked

A. caseous
B. fibrinoid
C. liquefactive
D. coagulative
E. none

A

D

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30
Q

Pre-neoplastic lesion

A. metaplasia
B. hyperplasia
C. anaplasia
D. dysplasia
E none

A

D

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31
Q

Ciliated columnar cells lining the bronchi transforming into squamous epithelium due to excessive cigar smoking is an example of:

A. metaplasia
B. neoplasia
C. dysplasia
D. anaplasia
E. none

A

A

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32
Q

The chromogen used in partnership with HRP

A. para dimethylaminobenzaldehyde
B. p-dimethyl-l-naphthylamide
C. diaminobenzidine
D. none

A

C

33
Q

Animal source for monoclonal antibody

A

MICE

34
Q

San galing polyclonal antibodies

A

RABBIT

35
Q

True of IHC except

A. used for drug development
B. to identify discrete tissue components
C. identification of antibodies in both paraffin
D. samples can be viewed using LM

A

C

36
Q

Can be used in proteolytic enzyme digestion in IHC

  1. lipase
  2. trypsin
  3. gelatinase
  4. protease

A. 1 and 3
B. 2 and 4
C. 1, 2, and 3
D. 1, 2, 3, and 4

A

B

37
Q

NOT an epithelial tumor marker

A. s-100 protein
B. PSA
C. CEA
D. TTF-1

A

A

38
Q

All are germ cell tumor markers except:

A. HCG
B. PLAP
C. myogenic tumor
D. APP

A

C

39
Q

Most commonly used to assess proliferation of tumor cells

A. Ki-67
B. CD68
C. LCA
D. PLAP

A

A

40
Q

Best screening marker for lymphoma

A

LCA

41
Q

Which can be helpful in the diagnosis of malignant fibrohistiocytic sarcoma

A. Ki-67
B. CD68
C. LCA
D. PLAP

A

B

42
Q

Found in neural secretory granules and can be a marker of neuroendocrine differentiation

A. synapthophisin
B. chromogranin
C. PCNA
D. HCG

A

B

43
Q

Marker for choriocarcinoma

A. synapthophisin
B. chromogranin
C. PCNA
D. HCG

A

D

44
Q

Optimal incubation time and temp for linking antibodies is at:

A. RT = 30-60mins
B. RT = 15-30mins
C. 37degC = 30-60mins
D. 42degC = 30-60mins

A

A

45
Q

Validity period of the DOH-LTO

A. 2yrs
B. 1yr
C. 3yrs
D. 6mos

A

B

46
Q

Responsible for policy-making and strategy formulating of the PH HIV AIDS policy act

A. secretary of health
B. president
C. PNAC
D. DOLE

A

PNAC

47
Q

Implementing arm of the DDB according to the Comprehensive Dangerous Drugs Act of 2002

A. PDEA
B. DOH
C. FDA
D. PRC

A

A

48
Q

Responsible for the regulation of blood services according to the Rules and Regulations Governing the Regulation of Blood Service Facilities

A. HFSRB
B. PDEA
C. DDB
D. DOH

A

A

49
Q

Classification of DTLs according to service capability

A. primary and secondary
B. screening and confirmatory
C. tertiary and quaternary
D. govt and private

A

B

50
Q

An individual included in the list of qualified voluntary blood donors who is ready to donate blood when needed in his/her community

A. voluntary donor
B. walking donor
C. donor
D. legatee

A

B

51
Q

Law that repealed RA 8504 and established the PH Natl AIDS Council (PNAC) as the planning, policy-making, and implementing body

A. RA 7719
B. RA 9165
C. RA 11166
D. RA 11223

A

C

52
Q

Minimum general avg required to pass the board exam

A

75%

53
Q

Minimum age requirement to be issued a certificate of registration (COR)

A

21 y/o

54
Q

How many months refresher course after failing 3 examinations

A

12months

55
Q

Magkano ung fee for the issuance of a certificate of registration (COR)

A

PHP150

56
Q

Minimum passing score for any major subject in the board exam

A. 40%
B. 45%
C. 50%
D. 55%

A

C

57
Q

Maximum period of suspension of the certificate of registration (COR)

A

2yrs

58
Q

Under present laws, pathologists are allowed to manage maximum of ilang laboratories / bloodbank?

A

4 lab
1 bloodbank

59
Q

The board may issue COR as Med Lab Tech w/out exam if:

A. application and payment of php20
B. passed civil service exam for medical technician given on march 21, 1965
C. finished 2-yr college course and has at least 1yr exp as medical technology technician
D. has failed to pass board exam but obtained general rating of at least 70%

A

D

60
Q

Functions and duties of the board except:

A. administer oaths
B. issue, suspend, and revoke CORs of medical technologists and medical technicians
C. look into conditions affecting the practice of MT in the PH
D. inspect diff medical technology schools in the country

A

D

61
Q

Qualifies an alien for the board exam except:

A. established reciprocity in the practice of the profession between PH and his/her country
B. 3yrs of permanent residence
C. curricula are substantially similar
D. dual citizenship

A

D

62
Q

To pass the board exam, a candidate must:

A. obtain gen avg of at least 75% in the written test
B. No rating below 50% in any major subj
C. has not failed in at least 60% of the subjects computed according to their relative weights
D. all of the above

A

D

63
Q

Which can perform red cell antibody screening

A. bloodbank
B. blood center
C. blood station
D. BCU

A

A

64
Q

Minimum requirement of lab personnel for screening drug laboratory

A. analyst, head patho, authorized spx collector
B. analyst, head patho
C. analyst, authorized spx collector
D. head patho, authorized spx collector

A

A

65
Q

NOT considered unlawful when mandatory testing is done

A. HIV testing
B. newborn screening
C. drug testing
D. paternity testing

A

C

66
Q

Who cannot practice MT in the PH?

A. Foreign professionals who are called by the govt for consultation, exchange profs, or instructors in the specialized branches
B. Foreign professionals who come to the PH by international convention
C. Foreigners who are allowed thru reciprocity
D. NONE

A

D

67
Q

Persons who may become legatees or donees except:

A. any hospital
B. any specified individual
C. organ bank storage facility
D. any clinical lab

A

D

68
Q

Exceptions to the confidentiality disclosure of HIV result except

A. reportorial requirements of DOH
B. informing other health workers directly involved in the treatment of a care of a PHLI???
C. nearest kin pf patient
D. responding to a subpoena issued by court

A

C

69
Q

Father of PAMET

A

Charlemagne Tamondong

70
Q

Under the ORGAN DONATION ACT OF 1992, which of the ff has the correct definition?

A. Decedent - an indiv authorized to donate all part of a decedent (next of kin, of legal age)
B. Testator - an indiv who receives a legacy or donation
C. Donor - an indiv authorized to donate all part of a decedent (next of kin, of legal age)
D. Legatees / Donees - deceased indiv, including a still-born infant or fetus

A

C

71
Q

Compulsory HIV testing are allowed in the ff except:

A. persons charged w/ serious and slight physical injuries, rape, or simple seduction
B. <15 y/o pregnant or engaged in high-risk behavior
C. resolution of issues under “The Family Code” in the PH
D. blood and organ donors

A

B

72
Q

The ff amended RA 5527 except:

A. RA 7719
B. RA 6138
C. PD 498
D. PD 1534

A

A

73
Q

The chairman of the TECHNICAL COMMITEE FOR MEDTECH EDUCATION

A. pamet pres
B. pasmeth pres
C. pasmeth member
D. PRC chairperson

A

B

74
Q

CMO 13 s.2017 states that all private HEIs intending to offer BSMT must first secure proper authority from

A. DOH
B. DepEd
C. PRC
D. CHED

A

D

75
Q

San Lazaro SACCL - STDs

RITM -

A. HIV/AIDS (indiv)
B. TTIs
C. cardiac markers
D. toxicology

A

B

76
Q

In AO 2021-0037, the minimum number of RMTs (including reliever) in a clinical lab operating in 8hrs is:

A

5

77
Q

Authenticates and allows the use of e-signature

A. DOH
B. PSP
C. DOST
D. DICT

A

D

78
Q

Newborn screening act

A. RA 11223
B. RA 10912
C. RA 4688
D. RA 9288

A

D

79
Q

Prohibited acts in the operations of clinical labs except:

A. making consistent errors in the performance of CL examinations
B. deviation from the standard test procedures including the uses of expired reagents
C. change in ownership, location, and HOL or lab personnel w/out informing the HFSRB
D. issuance of a lab report w/out the approval of the HOL

A

C

midterm exam (4 decks)

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