Histology- Week 9 Applied Anatomy Flashcards

1
Q

What is the difference between anatomy and physiology~?

A

Anatomy= structure and shape of the body, its parts and their relationship to one another Physiology= study of how the body and its parts work or function

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2
Q

What is Histology?

A

The study of the tissues of the body- cell types and their arrangements

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3
Q

In order of size work from atoms to molecules to organelles……all the way to a whole organism

A

Atoms - smallest chemical unit Molecules - groups of atoms joined together Organelles - groups of molecules working together Cells - groups of organelles working together Tissues - groups of similar cells working together Organs - group of different tissues working together Organ systems - group or organs working together Organism - an individual

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4
Q

What are organs made up of ?

A

Group of 2 or more tissue types working together

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5
Q

Name 5 of the 10 Systems that exist within the human body.

A

Skeletal system Muscular System Nervous System Endocrine System Cardiovascular System Lymphatic System Respiratory System Digestive System Urinary System Reproductive System

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6
Q

Can you identify the organelles of a generic animal cell and outline their functions?

A

Cell membrane- control movement of substances in and out

  • fluid mosaic model and phospholipid bilayer

Secretory Vesicles - carry secretions to cell membrane

Golgi Apparatus- modify and package proteins (sent to it by

RER via vesicles-pinch off into vesicles)

Ribosome - protein synthesis. in cytoplasm or RER

RER - assemble/distribute proteins (e.g. fold into functional 3-D

shapes)

Nucleolus - Produce ribosomes (assembled)

DNA - genetic material/blueprint contains instructions of body

Chromatin - When cell not dividing its DNA combines with

protein and forms a loose network of threads

called chromatin. Cell dividing-chromatin coil and

condense to form dense chromosomes.

Nucleur membrane - double membrane regulating movement

of substances in and out of nucleus.

Nucleus - Directs cell activity and cell division

SER - assemble and distribute lipids and detox of drugs

Centrosome/centriole - support/formation of microtubules

Cytoplasm - site of cellular activity diffusion/dissolve

substances/enzymes

Mitochondria - double membrane make energy (ATP)

aerobically

Lysosome - break down/digest substances using enzymes

  • abundant in phagocyte cells
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7
Q

Name five tissues of the body

A
  • Epithelium (surface and lining)
  • Connective tissue (packing and support)
  • Muscle (contractile)
  • Nerve (excitable)
  • Glia (support in CNS)
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8
Q

Name 3 examples of where general connective tissue can be found in the body

A
  • Dermis of skin
  • Tendons and ligaments
  • Deep and superficial fascia
  • (tendon) sheaths
  • blood vessel walls
  • surrounding the parenchyma of organs
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9
Q

What different classes of connective tissue are there in the body?

A
  • Cartilage
  • Blood
  • Bone
  • General
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10
Q

Name some examples of the function of connective tissue

A
  • Protection (delicate or tough)
  • Support
  • Tensile strength
  • Weight Bearing
  • Trasmitts tension
  • Allows movement
  • Provides recoil momentum
  • Provides nutrition
  • Defence and repair any damage
  • Conserve heat (insulating)
  • Storing reserve fluid and energy
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11
Q

What is the basic structure of connective tissue?

A

1) THE MATRIX or extracellular material

This is made up of a) ground substance and b) fibres

a) ground substance is made up of fluid and proteoglycans (protein and sugar molecules which hold water into a gel/jelly
b) fibres (protein) made up of collagen, elastin and reticular
2) CELLS such as fibroblasts, macrophages, mast cells, plasma cells and adipocytes (fat cells)

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12
Q

How is connective tissue classfied?

A

Loose (less fibres, more ground substance and more cells)

  • Areolar
  • Reticular (reticular fibres)
  • adipose (adipose cells storing lipid-insulating)

Dense (more fibres)

  • Regular (collagen fibres arranged in rows)
  • Irregular (collagen fibres arranged irregularly)
  • Elastic (elastin fibres)
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13
Q

What are the most common types of connective tissue found in the body?

A

Loose areolar- found just under epithelial tissue and wrapping around organs

Dense regular- found in tendons and ligaments

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14
Q

What is cartilage? How does it differ from bone?

A

Specialised connective tissue. Provide support to withstand compressive forces as well as having tensile strength

Cartilage is more flexible than bone and has greater shock absorbing qualities

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15
Q

Where in the body can cartilage be found?

A
  • Embryo-bones start as cartilage
  • Epiphyseal growth plates
  • Anterior parts of the ribs
  • Ends of bones in articular cartilage
  • Larynx, ear and nose
  • Rings in trachea and bronchi
  • In some joints as shock absorbers e.g. menisucs of knee
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16
Q

Name some functions of cartilage

A
  • shock absorption
  • retains form
  • increases congruency between bones
  • facilitates movement
  • joint formation
  • greoth plates
17
Q

Name the properties of cartilage

A
  • semi-rigid
  • slightly compressive
  • light
  • flexible
  • pliable
  • smooth, low friction
  • growth
18
Q

What does avascular and anerual mean-in the context of cartilage?

A

Avascular= no blood supply

Aneural = no nerves

19
Q

Name the cells of cartilage:

Cartilage cell are called…

Actively secreting cartilage cells are called…

What are they secreting?

Name the cells dissolving/digesting the matrix…

A

Cartilage cells= Chondrocytes

Secreting cells= Chondroblasts

Cells to dissolve/digest = Chondroclasts

20
Q

Name the three main types of cartilage

A

Hyaline

most common, weakest, glass-like, pliable, comnects ribs to sternum. ground substance rich in proteoglycans

Elastic

Similar to hyaline with more elastin fibres. malleable recoil. found where strength and stretch required e.g ears

Fibro

strongest. shock-absorbing, plenty of collagen, withstands pressure. e.g. disks between vertebrae stop bones grinding together.

21
Q

How do tendons differ from ligaments?

A

Tendons attach muscle to bone

Ligaments attach bone to bone at joints. Ligaments are more stretchy and contain more elastic fibres than tendons.

22
Q

What are the 6 functions of bone

A
  1. levers for movement
  2. muscle attachments
  3. support and shape
  4. protection
  5. calcium metabolism
    immunity/blood forming
23
Q

What are the properties of bone?

A
  • rigidity
  • light
  • able to grow
  • able to remodel
  • able to repair
  • strong
  • flexible
  • responsive
  • resist tensile and shearing plus compressive forces
24
Q

what are the cells of bone?

Bone cells are called…

Secreting bone cells are called..

Digesting bone cells are called…

A

Bone cells =Osteocytes

Secreting cells= osteoblasts

Digesting = osteoclasts

25
Q

What is the makeup of the matrix in bone?

A

Collagen fibres impregnanted with calcium phosphate and magnesium phosphate-giving bone its rigidity.

collagen gives tensile strength and some flexibility.

matrix is hard and insoluble (no diffusion)