Histology surface epithelium Flashcards

1
Q

protein of zona occludens that maintains barrier between adjacent cells and apical and lateral domains

A

Occludin

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2
Q

forms the backbone of each zonula occludens strand

forms the extracellular aqueous channels for paracellular passage of ions

A

claudins

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3
Q

formation of occluding junctions in endothelial cells betwwen endothelial cells amd monocytes
zipper and seal functions
barrier against paracellular diffusion

A

Junctional adhesion molecule (JAM)

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4
Q

pathway of substance transport that requires energy

across the plasma membrane of the epithelial cells

A

Transcellular pathway

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5
Q

across zonula occludens between two adjacent cells

A

paracellular pathway

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6
Q

The permeabilityy of occluding junction depends on:

A

molecular composition of aonula occludens strands
number of active aqueous channels
claudins

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7
Q

responsible for the formation of extracellular aqueuous channel

A

claudins

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8
Q

mechanical stability for epithelial cells
found on lateral cwll surface and basal domain of epithelial cells
structural unity
with signal transduction
cell to cell recognition
interacts with intrmediate filaments

A

Adhering or anchoring junction, zona adherens

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9
Q

part of every anchoring junction on. oth kayeral and basal cell surfaces

A

cell adhesion molecules (CAM)

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10
Q

allows cells to easily join and dissociate

A

selective adhesiveness

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11
Q

linked through a variety of intravellular proteins to components of cell cytoskeleton

A

cytoplasmic domains

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12
Q

transmembrane Ca+ dependent CAMS

regulate mechanisms of growth snd cell differentiation

A

Cadherins

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13
Q

interact with extracellular matrix molecules and with actin filaments of cytoskeleton
controls cell movement and shape

A

integrins

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14
Q

expressed on WBC wnd endothelial cells
mediate neutrophil-endothelial cell recognition
involved in directing lymphocytes

A

selectins

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15
Q

mediate homotypic cell to cell adhesion

A

Ig superfamily (IgSF)

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16
Q

for epithelial surface integrity
continuous band belt-like configuration
witn E cadherin

A

zonula adherens

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17
Q

anchoring crll to cell junction that provides a strong attchement

A

macula adherens (desmosome)

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18
Q

cytoplasmic bundles containing bundle

A

cillia

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19
Q

inter al structure found in the hair.ike extensionsof the apical plasma membrane

A

axoneme microtubule based

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20
Q

where axoneme. extends from centriole-derived microtubule

A

basal body

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21
Q

what are the classification of cillia?

A

motile
primary
nodal

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22
Q

numerous on the apical domain of many epithelial cells
with flagella to transports
erm
has 9+2 axonemal organization

A

motile cillia

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23
Q

solitary prijections found on eukaryotic cells
monocilia-single cilium per cell
immotile
chemosensors, light sensors, sound perception

A

primary ciliia (monocilia)

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24
Q

found in bilaminarembryonicdisc of the embryo(gastrulation)
surroundsprimitive node
performs rotational movement
for early embryonic development

A

nodal cillia

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25
Q

short, fine, hair-like structures

A

motil cilia

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26
Q

thin darkstaining band extending across the cell at the base of the cilia

A

basal bodies

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27
Q

from the tip of the cilium to its base

A

9+2 microtubule array

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28
Q

collar like extension between the transitional zone of basal body and plasma membrane

A

alar sheet (transitionak fiber)

29
Q

found in the midregion of thbasal body
for ciliary movement coordination
adjusting the badal bodies by rotating them

A

basal foot

30
Q

made of rootletin-containing protofilaments

projects and anchors the basal body within the apical cell cytoplasm

A

striated rootlet

31
Q

based on the movement of th doublet microtubules

A

ciliary activity

32
Q

initiated by dynein arms

exhibits rapid forward movement

A

ciliary activity

33
Q

cilia becomes flexible

slower return movement

A

recovery stroke

34
Q

moving mucus over epithelial surfaces

flow of fluid and other substances through tubular organs and ducts

A

cilia metachronal rhythm

35
Q

only one cilium
found on rete testis
ependymal cells cavities of CNS

A

primary cells

36
Q

cytoplasmic processes containing a core of actin filaments

A

microvili

37
Q

unusually long, immotile microvilli that extends from apical surfaces
found on epididymis
ductis deferens
sensory hair

A

stereocilia

38
Q

unusually long motile microvilli
resembles the hairs of a paint brush
supported by internal bundles of actin filaments cross-linked by fimbrin

A

streovilli

39
Q

impermeable
allow epithelial cells to function as a barrier
for primary intercellular diffusion barrier
prevent migration of lipids

A

Zona occludens

40
Q

Interface between dupport tissues and parencyma

A

Compartmentalization

41
Q

initiates development of basal lamina

A

Laminins

42
Q

Used to identify the basement membrane

A

Periodic acid schiff (PAS)

43
Q

main layer of basal lamina

A

Lamina densa

44
Q

major component of the basal lamina proteins

A

type IV collagen

45
Q

anchoring fibrils that link basal lamina to reticular lamina

A

Type VII

46
Q

stabilizing lamina in skeletal and cardiac muscle

A

Type XV

47
Q

in vascular and epithelial basal laminae for angiogenesis

A

Type XVII

48
Q

involved in he cell to extracellular matrix interactions
for basal lamina assembly
for development differentiation and remodeling of epithlium

A

laminins

49
Q

link between laminin and the type IV collagen network
bind Ca+
support cell adhesion
promote neutrophil chemotaxis and phgocytosis

A

Entactin/Nidogen

50
Q

pathway in between cells

A

paracellular pathway

51
Q

pathway through cells

A

transcellular pathway

52
Q

hearing receptors

mechanoreceptors

A

streocilia

53
Q

type of cilia that can move separately

passive

A

micorvilli

54
Q

has cytoplasmic ridges

moves dependently

A

streocillia

55
Q

seen on skin, cornea

A

ectoderm

56
Q

seen in alimentary tract, liver and pancreas

A

endoderm

57
Q

seen in kidneys, reproductive tissues, endothelium and mesothelium

A

mesoderm

58
Q

between basal lamina and th cell

clear tand electron lucent area

A

Lamina lucida

59
Q

layers composed of cells covering the extertior body surfaces

A

basal lamina

60
Q

an arifact, not a true layer

A

lamina lucida

61
Q

numerous on th apical domain of many epithelial cells

posses 9+2 axonemal organizAtion

A

motile cilia

62
Q

solitary projections found on eukaryotic cells
connecting stalks of photorceptor cells
ependymal cells lining fluid-filled cavities pf CNS

A

primary cilia (monocilia)

63
Q
found in bilaminar embryonic disc pf the embryo
gastrulation
surrounds primitive node
perform rotational movement
for early embryonic develoment
A

nodal cilia

64
Q

cilia + basal bodies

A

ciliary apparatus

65
Q

site of microfilAment is in the?

A

Zona adherens

66
Q

maintain the morphologic integrity of the epithelium-connective tissue interface

A

anchoring junctions

67
Q

anchor actin filaments of th cytoskeleton into the basement membrane

A

focal adhesio s

68
Q

anchor intermediate filaments of th cytoskeleton into the basement membrane

A

hemidesmosomes

69
Q

amino acid sequence of the cytoplasmic portions of all three proteins

A

PDZ-domain proteins