Histology of the Ovary Flashcards

1
Q

what is the ovarian cortex?

A

the area around the outside
where the follicles are
(business end)

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2
Q

what are the supporting cells for oocytes?

A

(service area)

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2
Q

what are the primordial follicles?

A

the very first stage of development
dormant and a few develop and differentiate at puberty
present from birth

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3
Q

how do we classify primordial follicles?

A

they only have one layer of follicles

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4
Q

what is the zone pellucida?

A

glycoprotein coat that surrounds the developing oocyte

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5
Q

what is the antrum?

A

fluid filled space

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6
Q

what are the follicular cells that are closest to the developing oocyte called?

A

follicular granulose cells

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7
Q

what are the follicular theca cells?

A

go all the way around the follicle
go all around the outside edges

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8
Q

what do the theca cells produce?

A

androgens which get passed to the granulose cells

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9
Q

how do the granulose cells produce oestrogens?

A

they have an enzyme called aromatase which converts androgens to oestrogens

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10
Q

what does mallory stain do?

A

stains red blood cells an orangey red colour

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11
Q

what are the 2 types of theca cells?

A

theca interna and externa

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12
Q

which internal cells contain all the blood vessels?

A

theca interna
closest to the antrum

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13
Q

what is the theca externa?

A

external wall of the follicle

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14
Q

when can we call the follicle a secondary follicle?

A

when it has developed an antrum

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15
Q

what is follicular atresia or spontaneous degeneration?

A

hormonally controlled cell death
granulose cells die first and they can’t support the oocyte so the follicle will die

16
Q

what is the corpus luteum?

A

endocrine structure that supports a pregnancy
collapsed follicles
produces lots of progesterone

17
Q

what characterises luteal cells?

A

have a central nucleus and they radiate out from the centre
lots of cytoplasm with white spaces that is fat

18
Q

why do the luteal cells have fat present?

A

building blocks of steroid hormones is cholesterol
these must have fat in order to make lots of hormones

19
Q

why does the theca internal have many blood vessels?

A

play an important part in the formation of the corpus luteum if the follicle proceeds to ovulation

20
Q

what enzyme converts androgens to oestrogens in the follicle?

A

aromatase

21
Q

where do the lutein cells arise from?

A

granulosa and theca cells