Histology Of Ovary Flashcards
The ovary is covered by a single layer of cuboidal (almost squamous cells) known as
Germinal épithélium
Epithelium is continuous with mesothelium lining the —-
Mesovarium
A dense connective tissue layer called the ———— lies between the germinal layer and the cortex
Tunica albuginea
Cortex consists of
Connective tissue stroma
Scattered smooth muscle fibres present in stroma around the follicles
ovarian follicles
Medulla contains
Loose connective tissue Blood vessels Nerves Lymphatics Located in central portion of ovary
Hilus cells of medulla are similar to interstitial cells of testis and secrete
Androgens
Why is the germinal epithelium misnomer
The epithelium does not produce germ cells
Oogonia develop from
primordial stem cells in Yolk sac endoderm
Primary oocyte is arrested at
Prophase of 1st meiosis
Primary oocyte completes the first méiotic division just before ———
Ovulation
Secondary oocyte remains arrested at ——— till fertilisation occurs
Metaphase
Ovulation takes place while the oocyte is in _______
Metaphase
Primordial follicle
Primary oocyte surrounded by follicular cells (flattened squamous cells)
Oocyte arrested in prophase of meiosis 1
The outer surface of these cells is separated from connective tissue by basal lamina
Primary follicle
Flattened follicular cells become cuboidal
Zona pellucida appears between the follicular cells and the oocyte
Late primary follicle
Multilayered mass of granulosa cells surrounding the oocyte
Innermost Layer of granulosa cells is adjacent to zona pellucida
The outermost layer of these cells rests on the Basal lamina which is adjacent to the stroma cells
Secondary follicle
Antrum filled with follicular fluid is visible in stratum granulosum
Multiple layers of theca interna cells and theca externa cells can be seen outside the basal lamina of the secondary follicle
Theca interna
Theca externa
Theca interna: cellular layer, cells are epithelium
Display the characteristic of endocrine cells steroid secreting cells
Theca externes
Connective tissue layer
Cells are spindle shaped
Graafian follicle
The antral cavities coalesce to form one large cavity
The follicle increases in size
Oocyte surrounded by a mould of follicular cells called cumulus oophorus
Follicular cells that surround the Antral cavity are referred to as the membrana granulosa
Corpus luteum
After ovulation the walls of the follicle collapses and becomes infolded
Blood vessels and stromal cells now invade the granulosa cells
The granulosa cells and theca interna cells become large and accumulate lipid
Become pale staining
