Histology of muscle Flashcards
Types of skeletal muscle connective tissue:
- Epimysium: surrounds entire muscle
- Perimysium: surrounds each fascicle
- Endomysium: surrounds each fibre/muscle cell.
Structure of skeletal muscle fibre
- Long unbranched cylindrical shape
- Multinucleated
- Nuclei positioned peripherally
- Striated
Thin (actin) filaments
From from Z disc to centre of sarcomere
Thick (myosin) filaments
In the centre of the sarcomere, contain ATPase enzymes.
A bands
Full length of thick filament (including parts of thin filament)
H zone
Centre part of A band, no thin filament.
M line
Centre of H zone
I band
Only thin filaments, lies within 2 adjacent sarcomeres.
T tubules
Runs around myofibrils in sarcolemma, makes sure all myofibrils contract simultaneously.
Sarcoplasmic reticulum
Interconnecting tubules surrounding each myofibril. Contains Ca2+
Nerve impulse direction in muscle
T-tubule –> release of Ca2+ from sarcoplasmic reticulum –> Ca2+ into cytoplasm –> contraction.
Sliding filament theory
- Thin filaments are pulled towards the centre of the sarcomere
- Sarcomere shortens
Smooth muscle cell structure
- Fibres are shorter than skeletal
- Spindle shaped
- Single nucleus in centre.
- No myofibrils or sarcomeres, so not striated
- Thin + thick filaments are scattered + attached to dense bodies throughout the sarcoplasm
- Have calveolae
Dense bodies
noncontractile intermediate filaments
Caveolae
Indentations in sarcolemma that act like T tubules.