Histo Vessels Flashcards
What are the three layers or coats that make up the wall of blood and lymphatic vessels?
Tunica Intima, Tunica Media, and Tunica Externa (Adventitia).
What is the structure of the tunica intima?
It is the innermost layer close to the lumen, made of endothelium (simple squamous epithelium) resting on a basal lamina with a subendothelial layer of loose connective tissue and an internal elastic lamina.
What is the composition and function of the tunica media?
It is composed of circular smooth muscle cells, elastic and reticular fibers. The smooth muscle cells regulate the diameter of the lumen, influencing blood pressure and flow.
What are the characteristics of large elastic (conducting) arteries like the aorta?
They have a thick tunica media with fenestrated elastic lamina and circular smooth muscle. The tunica externa is underdeveloped.
Why do major elastic arteries contain a large amount of elastic fibers?
Elastic fibers enable major arteries to stretch and accommodate the blood ejected from the heart during ventricular contraction.
What happens to arteries in atherosclerosis?
The tunica intima thickens due to cholesterol deposits and smooth muscle proliferation, leading to decreased elasticity, aneurysms, and possible rupture.
What is the structure of medium-sized muscular arteries?
Examples include the brachial, femoral, and renal arteries. They have a prominent internal elastic lamina, thick tunica media with smooth muscle, and a clear external elastic lamina.
What is the function of medium-sized muscular arteries?
They distribute blood to different body parts and regulate blood flow through their muscular walls under autonomic nervous system control.
What are the characteristics of arterioles?
Arterioles have a diameter greater than 0.1mm, with 1-5 layers of circular smooth muscle in the media, and a scant adventitia.
What are metarterioles, and where are they located?
Metarterioles are intermediate between arterioles and capillaries, containing interrupted layers of smooth muscle cells with precapillary sphincters.
What is the structure of capillaries?
Small, thin-walled blood vessels with a luminal diameter of 8-10μm, made of a single layer of endothelial cells on a basal lamina, with pericytes aiding in contraction.
What are the different types of capillaries?
Continuous (tight junctions), Fenestrated (with or without diaphragm), and Sinusoids (large endothelial fenestrations).
What are venules, and what is their function?
Venules are small veins that collect blood from capillaries. Their tunica media contains a few smooth muscle cells and fibroblasts, allowing phagocytic white blood cells to escape.
What are the characteristics of medium-sized veins?
These veins have thinner walls than arteries, a thicker adventitia, and contain valves to prevent blood backflow.
How do medium-sized arteries differ from medium-sized veins?
Arteries have thick walls and narrow lumens without valves, while veins have thin walls, wide lumens with valves, and thicker adventitia.