Histamine Antagonists Flashcards

1st-2nd-3rd Generation Antagonists

1
Q

diphenhydramine

A

first generation

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2
Q

chlorpheniramine

A

first generation

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3
Q

cyclizine

A

first generation

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4
Q

cyproheptadine

A

first generation

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5
Q

promethazine

A

first generation

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5
Q

loratidine

A

second generation

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5
Q

chlorpheniramine

A

first generation

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5
Q

cyproheptadine

A

first generation

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5
Q

cyclizine

A

first generation

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6
Q

terfenadine

A

second generation

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7
Q

cetirizine

A

second generation

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8
Q

desloratidine

A

third generation

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9
Q

fexofenadine

A

third generation

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10
Q

They are - sedating agents, can pass BBB, short duration

A

first generation antihistamine

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11
Q

They are- non-sedating, cannot pass BBB, long duration

A

second generation antihistamines

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12
Q

They are- derivatives of second generation drugs intended to have increased efficacy with fewer adverse drug reactions

A

Third generation antihistamines