Histamine Antagonists Flashcards
1st-2nd-3rd Generation Antagonists
diphenhydramine
first generation
chlorpheniramine
first generation
cyclizine
first generation
cyproheptadine
first generation
promethazine
first generation
loratidine
second generation
chlorpheniramine
first generation
cyproheptadine
first generation
cyclizine
first generation
terfenadine
second generation
cetirizine
second generation
desloratidine
third generation
fexofenadine
third generation
They are - sedating agents, can pass BBB, short duration
first generation antihistamine
They are- non-sedating, cannot pass BBB, long duration
second generation antihistamines
They are- derivatives of second generation drugs intended to have increased efficacy with fewer adverse drug reactions
Third generation antihistamines