Hirschsprung's Disease

Question 1

Failure to pass meconium within … h should raise suspicion of Hirschsprung’s disease. The sign of explosive diarrhoea following digital rectal examination is highly suggestive of Hirschsprung’s disease. The definitive investigation is rectal suction biopsy and histological examination.

Answer 1

Failure to pass meconium within 48 h should raise suspicion of Hirschsprung’s disease. The sign of explosive diarrhoea following digital rectal examination is highly suggestive of Hirschsprung’s disease. The definitive investigation is rectal suction biopsy and histological examination.

Question 2

Failure to pass meconium within 48 h should raise suspicion of Hirschsprung’s disease. The sign of explosive diarrhoea following digital rectal examination is highly suggestive of Hirschsprung’s disease. The definitive investigation is …

Answer 2

Failure to pass meconium within 48 h should raise suspicion of Hirschsprung’s disease. The sign of explosive diarrhoea following digital rectal examination is highly suggestive of Hirschsprung’s disease. The definitive investigation is rectal suction biopsy and histological examination.

Question 3

Failure to pass meconium within 48 h should raise suspicion of …

Answer 3

Failure to pass meconium within 48 h should raise suspicion of Hirschsprung’s disease. The sign of explosive diarrhoea following digital rectal examination is highly suggestive of Hirschsprung’s disease. The definitive investigation is rectal suction biopsy and histological examination.

Question 4

Hirchsprung’s Disease

Answer 4

As the baby develops in utero, the distal colon is not innervated correctly. The resulting aganglionic colon is shrunken and not able to distend properly. This causes a back pressure of stool trapped in the more proximal colon.