Hippocampus: Anatomy/ hippocampal afferents

Question 1

Entorhinal cortex projects to

Answer 1

dentate gyrus, CA3, CA1

Question 2

What projects to dentate gyrus, CA3, and CA1?

Answer 2

Entorhinal cortex

Question 3

Entorhinal receives input from

Answer 3

a. amygdala
b. various areas of limbic system
c. all association areas of brain either directly or indirectly via perirhinal and parahippocampal cortex

Question 4

What receives input from the amygdala, various areas of limbic system, all association areas of brain either directly or indirectly via perirhinal and parahippocampal cortex

Answer 4

Entorhinal cortex

Question 5

Subcortical input comes through

Answer 5

fornix

Question 6

Subcortical input to

Answer 6

hippocampus

Question 7

Dopamine input from

Answer 7

ventral tegmental area - mediates reinforcement

Question 8

Norepinephrine from

Answer 8

locus coeruleus - aruosal

Question 9

Acetylcholine from

Answer 9

Medial septum - arousal: 1. Ach theta waves to the hippocampus

2. Ltp occurs at peak of wave
3. Lt depression occurs at trough

Question 10

Subcortical systems regulate the functioning of the

Answer 10

Hippocampus

Question 11

Subcortical input to hippocampus

Answer 11

a. subcortical input comes thru fornix
b. dopamine input from ventral tegmental area – mediates reinforcement
c. norepinephrine from locus coeruleus – arousal
d. serotonin from raphe` nucleus – arousal et al
e. acetylcholine from medial septum – arousal
1. Ach theta waves to the hippocampus
2. Ltp occurs at peak of wave
3. Lt depression occurs at trough
f. these subcortical systems regulate the functioning of the hippo