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Immuno > HighYield > Flashcards

HighYield Flashcards

1
Q

What foods are in the Prolamin superfamily?

A

seed storage proteins (seeds, tree nuts, legumes - CEREALS) ; lipid transfer proteins, alpha amylase/protein inhibitors)

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2
Q

What foods are in the cupin superfamily?

A

7s vicillin and 11s globulins (seeds, tree nuts, legumes)

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3
Q

Which foods are in the PR10 superfamily?

A

Betv1: apple, pear, stone fruits, celery, soybean, peanut

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4
Q

Milk allergen name

A

Bos d - casein, lactalbumin

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5
Q

Egg allergen name

A

Gal d - vovomucoid, ovalbumin, ovotransferrin

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6
Q

Wheat allregen name

A

Tri a

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7
Q

Peanut allergen name

A

Ara h

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8
Q

Shrimp allergen name

A

Lit v 1 (myosin Light chain), Pen a 1 (troPomyosin)

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9
Q

Fish allergen name

A

Gad c 1 (parvalbumin)

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10
Q

Soy allergen name

A

Gly m

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11
Q

Hazelnut allergenname

A

Cor a 8,9

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12
Q

Apple allergen name

A

Mal d

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13
Q

Legume and legume reaction risk?

A

5%

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14
Q

Tree nut and tree nut reaction risk?

A

37% (12-37%) ** must know on boards

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15
Q

Fish and other fish reaction risk?

A

50% (30-75%)

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16
Q

Shellfish allergy and other shellfish reaction risk?

A

75%

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17
Q

Grain allergy and other grain reaction risk?

A

20%

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18
Q

Cow’s milk allergy and beef reaction risk?

A

10%

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19
Q

Cow’s milk allergy and goat’s milk reaction risk?

A

92%

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20
Q

Cow’s milk allergy and mare’s milk reaction risk?

A

4%

21
Q

Pollen allergy and fruits/veg reaction risk?

A

55%

22
Q

Peach allergy and other Rosacea reaction risk?

A

55% (P3AC: peach, plum, pear, apple, cherry)

23
Q

melon allergy and other fruits reaction risk?

A

92%

24
Q

latex allergy and fruits reaction risk?

A

35%

25
Q

egg allergy and chicken allergy risk?

A

22-32%

26
Q

Crustacean allergy and other crustacean risk?

A

38% (35%)

27
Q

crustacean allergy and mollusk risk?

A

14% (15%)

28
Q

mollusk allergy and other mollusk risk

A

49% (50%)

29
Q

tree nut and peanut (legume) risk

A

35%

30
Q

peanut and soy allergy risk

A

5%

31
Q

Almond pair with?

A

Almond and Hazelnut

32
Q

Lentil pairs with?

A

Lentil and chickpea

33
Q

Pecan pairs with?

A

Pecan and walnut

34
Q

Hazelnut pairs with?

A

Hazelnut and almond

35
Q

What is the size of a grass pollen allergen?

A

20-45 micrograms

36
Q

Papain vs Pepsin

A

PApAin cleave Above hinge: 2 fab, 1 Fc

Pepsin cleaves below hinge: (fab)2

37
Q

Different between Fab one Fab2

A

Fab can bind and not cross link; Fab2 cannot bind or crosslink
- neither can fix complement or bind to the Fc receptor on the cell surface

38
Q

What is the difference between DNA-PK and ku?

A
  • DNA-PK: opens up hairpins at coding ends

- ku: binds broken DNA ends and recruits DNA-PK: “Think broKU DNA ends”

39
Q

Which cells secrete surfactant in the lung?

A

Type 2 alveolar cells

40
Q

What are the TCA antidepressants?

A

amitriptyline, nortriptyline, imipramine

41
Q

Effective doses for standardized pollens?

A

RaCe to the GDP(B)

  • RW: 1000-4000 AU
  • Cat: 1000-4000 BAU
  • Grass: 1000-4000 BAU
  • DM: 500-2000 AU
  • Bermuda: 300-1500 BAU
  • Venom: 100mcg single; 300 mcg mixed
42
Q

What is the effective dose for dog allergen in AIT?

A

15 micrograms of Can f 1

“My dog weighs 15 lbs”

43
Q

What is the effective dose for short ragweed allergen in AIT?

A

6-12 microgram of Amb a 1

44
Q

Which HLA , cytokines, and complement regulatory proteins are placental specific?

A
  • HLA-E, F, G
  • PGE2, IL-10, Il-4 - regulatory cytokines
  • CD46, DAF - prevent complement activation
45
Q

Muscarinic Receptor functions

A

M1: eosinophils in COPD; found in ganglia and mast cells
M2: Inhibitory rec on parasympathetic nerves: decreased in viral infections, increased Ach
M2: primary mediator of smooth muscle contraction in human airways - increases intracellular Ca, casting bronchoconstriction
– H1 blockers can have AntiAch effects via M3 receptor

46
Q

Steroid drug metabolism

A 
INCREASE LEVELS:
Cathy TROLls UP the RITunda looking to Kates Birth Control
- Clarithromycin
- troleandromyecin
- increase steroid levels 
- Ritonavir (Protease Inhibitor)
- Ketoconazole 
- OCP
47
Q

Sulfa antibiotic versus antibiotic: what is the difference?

A

Non-antibiotic does not have the aromatic amine at the N4 position (and why there is little cross reactivity)
- Sulfa antibiotic: SO2NH2 moiety

48
Q

Which extract has slow release of allergen?

A

Alum - works through the NLRP3 system

Immuno (2 decks)

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