High-Yield Facts Flashcards
DIG FAST
D = Distractibility and easy frustration I = Irresponsibility and erratic uninhibited behavior G = Grandiosity
F = Flight of ideas A = Activity increased with weight loss and increased libido S = Sleep is decreased T = Talkativeness
SIG E CAPS
S leep changes: increase during day or decreased sleep at night I nterest (loss): of interest in activities that used to interest them G uilt (worthless): depressed elderly tend to devalue themselves
E nergy (lack): common presenting symptom (fatigue)
C ognition/C oncentration: reduced cognition &/or difficulty concentrating
A ppetite (wt. loss); usually declined, occasionally increased
P sychomotor: agitation (anxiety) or retardations (lethargic)
S uicide/death preocp.
1 manic or mixed episode for 7 days or hospitalization
BPAD I
Hypomanic episode + MDD
BPAD II
3/7 DIGFAST x 1 week or hospitalization, 4/7 if mood is irritable
BPAD I
3/7 DIGFAST x 4 days
BPAD II
MDD criteria
depressed mood OR anhedonia
+
4/8 SIGECAPS x 2 weeks
Distinction of MDD from adjustment disorder
Excessive guilt, worthlessness, psychomotor retardation, suicidality
Time limits of Adjustment Disorder
3 months within stressor, persisting up to 6 months
Atypical depression criteria
Leaden paralysis, hypersomnia, hyperphagia, reactive, rejection sensitivity
Rx for atypical depression
SSRI –> another SSRI –> MAO-I
Worst type of schizophrenia
DIsorganized (negative sx difficult to treat)
Best prognosis of schizophrenia
Paranoid (positive sx easier to tx)
Residual schizophrenia
Neg > pos, “burnout”
5 core symptoms of schizophrenia
> 2 for >1 month: delusions, hallucinations, disorganized speech, disorganized behavior, negative symptoms
OR
Bizarre delusions AH of running commentary AH of two voices conversing Alienation of thought Magical thinking Control
4 side effects of clozapine
Agranulocytosis (stop if WBC <1500); myocarditis; seizures; NMS
Side effect of lamotrigine
SJS, TEN
Side effects of Carbamazepine
SIADH, aplastic anemia, agranulocytosis
Causes of akathisia
Typicals, SSRIs, risperidone, aripiprazole
Symptoms of NMS
Lead-pipe rigidity, fever, autonomic instability, MS changes, leukocytosis, high CPK, rhabdomyolysis, renal failure
Treatment of NMS
Dantrolene, bromocriptine, hydration
Serotonin Syndrome
Fever, N/D, autonomic instability, myoclonus
Causes of SS
linezolid (antibiotic), tramadol (analgesic), SSRI, SNRI, TCA, MAOI), meperidine, triptans, dextromorphan, St. John’s wort
Treatment of HTNsive crisis
Phentolamine, nitroprusside
Indications for hemodialysis with lithium tox
seizure, delirium, stupor, coma
Mild lithium toxicity
Tremor, N/V, confusion, weakness, nystagmus, anorexia, stupor
Moderate lithium tox
Convulsions, oliguric renal failure
Severe lithium tox
Coma, CV collapse
Lithium side effects
Tremor, hypothyroidism, nephrogenic DI, acne, weight gain, leukocytosis, Ebstein’s anomaly in pregnancy
Valproate side effects
Thrombocytopenia, hair less, sedation, weight gain, tremor, dizziness, hepatotoxicity, pancreatitis, neural tube defects
Mesolimbic system
+ symptoms of schizo, too much DA
Mesocortical system
- symptoms of schizo, too little DA
Symptoms of PTSD/acute stress disorder
1) re-experiencing (nightmares, flashbacks) 2) hyperarousal (hypervigilant, on edge) and 3) avoidance/numbing, but acute stress also requires symptoms of dissociation
MDD v. bereavement
The key here is severity..Symptoms suggesting that bereavement has crossed into MDD are 1) excessive guilt 2) active SI 3) worthlessness 4) psychomotor retardation, 5) AH/VH other than seeing the deceased loved one [VH can occur in up to 30% of “normal” bereavement])
Complicated grief
> 6 mo., ambivalent relationship to deceased
Dysthymic disorder
depression + 2 of (ACHEWS [allergic to happiness] ↓/↑ appetite, ↓ concentration, hopeless, ↓ energy, worthless, ↓/↑ sleep) x 2 yrs. w/o intervening period of 2 months of euthymia
MDD with psychotic features
Psychosis only during depressive episodes
BPAD with psychotic features
Psychosis in either state
Schizoaffective
> 2 weeks of psychosis without mood symptoms
Cyclothymia
persistent mood episodes on most days for ≥ 2 yrs. straight without an intervening period of 2 mos. euthymia.
Social phobia
Intense fear of negative evaluation + avoidance