Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

immunology and serology high yield facts > HIGH YIELD > Flashcards

HIGH YIELD Flashcards

1
Q

ENHANCEMENT OF PHAGOCYTOSIS BY COATING OF FOREIGN PARTICLES WITH SERUM PROTEINS

A

OPSONIZATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Jenner’s work with cowpox which provided immunity against smallpox demonstrates

A

CROSS IMMUNITY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The structure formed by the fusion of engulfed material and enzymatic granules within the phagocytic cell

A

phagolysosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Two primary lymphoid organs

A

Bone marrow and thymus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Receptor on T cells responsible for rosetting with sheep RBC

A

CO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Antigen binding sites in typical IGM

A

10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Antibody best at agglutination and complement fixation

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Also known as T cell growth factor

A

IL-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The classical complement pathway is activated by

A

Ag-Ab complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Role of properdin in the alternative pathway

A

Stabilization of C3/C5 convertase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Factor H acts by competing with __ for the same binding site

A

Factor B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A technologist who observes a red rash on her hands after removing her gloves

A

LAtex allergy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In the chain of infection, a contaminated work area would serve as

A

Source

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The only biological waste that does not have to be discarded in a container with a biohazard symbol

A

urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

AN employee who receives an accidental needle stick should immediately

A

notify a supervisor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The first thing to do when acid is spilled on the skin is to

A

flush area with water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

When. combining acid and water

A

Acid is added to water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

To determine the chemical characteristics of sodium azide an employee would consult the

A

MSDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Normal ratio of CD4 and CD8

A

2:1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Orchestrator or master regulator of the immune system

A

Helper T cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Refer to as the leukocyte common antigen (LCA)

A

CD45

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Referred to as the common acute lymphoblastic leukemia antigen (CALLA)

A

CD10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Immature dendritic cells within the epidermidis

A

Langerhans cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

MHC-1 restricted T cell that recognizes endogenous peptides

A

Cytotoxic T cell (CD8)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

MHC-II restricted T cell that recognizes exogenous peptides

A

Helper T cell (CD4)

26
Q

Change in the class of antibody being produced by the plasma cell

A

Isotype switching

27
Q

Change in the class of antibody being produced by the plasma cell

A

Isotype switching

28
Q

Efficiency of immunoglobulin G transfer across placenta

A

IgG1>IgG3>IgG4>IgG2

29
Q

Immunoglobulin that can activate the Alternative pathway

A

IgA

30
Q

Also know as millionaire antibody

A

IgG

31
Q

Immature lymphocytes that recognize self-antigens in the central (generative) lymphoid organs are killed by apoptosis

A

Central tolerance/ Clonal deletion

32
Q

Mature lymphocytes that recognize self-antigens in peripheral tissues become functionally inactive

A

Peripheral tolerance/ Clonal anergy

33
Q

CREST syndrome

A

anti-centromere

34
Q

X-linked immunodeficiency disorder characterized by the failure of B-cell precursors (pro-B cells and pre-B cells) to mature into B cells

A

Bruton’s Agammaglobulinemia

35
Q

Risk of transmission of HIV is ___ with needle stick injury whereas the risk of hepatitis B is 30%

A

0.03%

36
Q

Potential reservoir of HIV

A

Follicular dendritic cell

37
Q

Most common cancer seen in px with AIDS

A

Kaposi’s sarcoma

38
Q

Most sensitive SCREENING test for HIV

A

ELISA

39
Q

Most specific CONFIRMATORY test for HIV

A

Western Blot

40
Q

Most important initial test before considering a kidney transplant donor

A

Test for ABO

41
Q

The only blood group system that affects clinical transplantation

A

ABO

42
Q

HSV generally found in and around the ORAL cavity and in skin lesions that occur above the waist

A

HSV-1

43
Q

Cross-reacting herpes

A

HSV-1 and HSV-2

44
Q

HSV isolated primarily from the genital tract and skin lesions below the waist

A

HSV-2

45
Q

Potential marker for stone disease
Cytokine that induces secretion of Ig and is a major factor in induction of the acute phase rnx; originally called interferon-B2 or B cell-stimulating factor-2

A

IL-6

46
Q

Information about the patient such as name, gender, age, or birth date, referring or attending physician

A

Patient demographics

47
Q

Anticoagulant for microlymphocytotoxicity testing

A

Acid citrated dextrose (ACD)

48
Q

Lymphocyte population

A

TBNK
T-cells (60%-80%)
B-cells (10%-20%)
NK cells (<10%)

49
Q

Complement-dependent cytotoxicity uses this type of microscope

A

Inverted phase contrast microscope

50
Q

IN fluorescence polarization immunoassay (FPIA) the degree of fluorescence polarization is ____ proportional to concentration of analyte

A

INVERSELY

51
Q

Hallmark rash of measles infection; bluish white spots with a red halo located on the buccal or labial mucosa

A

Koplik’s spot

52
Q

Antigenic determinant

A

EPITOPE

53
Q

Part of the antibody that binds to the antigen

A

PARATOPE

54
Q

Immortal cell that produces antibodies
Plasma cell fused with myeloma cells

A

HYbridoma cells

55
Q

Classic procedure for determining the HLA phenotype

A

Complement-Dependent Cytotoxicity test

56
Q

Acute phase reactant that is useful as a marker of sepsis and is utilized for differentiating bacterial and non-bacterial meningitis

A

PROCALCITONIN

57
Q

Gold standard in testing for contact dermatitis

A

PATCH TEST

58
Q

Gold standards of EBV serology methods

A

IFA (Indirect Immunofluorescence Assay)

59
Q

Gold standard for enumerating CD4 T cells

A

Immunophenotyping with flow cytometry

60
Q

Gold standard for detecting hepatitis C virus and monitoring therapy

A

RT-PCR

immunology and serology high yield facts (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions