High risk Prostate Flashcards
1
Q
Stampede Trial
A
Phase III, Randomized trial
High risk prostate, locally advanced pts
to see long term hormone therapy results
4 arms
1
Q
RT01 Trial
A
Phase III, randomized
T1b-T3a
PSA > 50
.
.
.
Std dose
64Gy in 32 Fx
BFS: 43%
10 yr PFS: 61%
OS: 71%
MFS: 82%
.
.
.
Escalated dose
74Gy in 37 Fx
BFS: 55%
10 yr PFS: 69%
OS: 71%
MFS: 83%
.
.
Escalated dose had better Biochemical progression free survival
Better 10 year PFS
