Hgb-oops

Question 1

How do Hemoglobinopathies form?

Answer 1

Defective amino acid sequencing via exchange/deletion/addition in a globin chain

Question 2

What’s the amino acid defect that causes Hgb S?

Answer 2

Beta- globin defect resulting in a substitution of Glutamic Acid by Valine (β6 Glu —> Val)

I just think of any Skyrim-ish name, Svarig vs “S-Val-Hgb”