Hfpef Flashcards
Estimated prevalence of hfpef among pt with HF
55%
Rf for hfpef
Age, females, Htn obesity
Mortality on hfpef?
About half the mortality of systolic HF. 50% die from non cv causes
Physiologic measurement of diastolic dysfunction
Tau. 1/slope of log lvp/time
Normal <40 ms
Relaxation complete by 3.5 tau
What decreases tau
Catecholamines (phosphorylates phospholamban), increased heart rate
Name six things that lengthen tau
Age, afterload hypertrophy, systolic heart failure, ischemia, asynchrony
Prevalence of ph in hfpef
80%
Class I guidelines hfpef
BP <130/80
Control tachycardia
Reduce central blood volume
Class iia coronary revascularization
What anti hypertensive should you use in hfpef?0
Look for other diseases: Htn, dm, cad, Afib with rvr
Hfpef death
30 from non cardiovascular disease
25% die of sudden death.
What does Afterload do to tau
It lengthens it
Tau is 1/slope of lvp time
What improves tau
Heart rate, cathecholamines
Normal tau
<40
What is the effect of impaired relation with exercise
Very important to keep heart rate low, as they have limited time
Abn e prime
E/e prime
<.06
E/e prime less than 15 normal. > 15. Higeher filling pressures
