HF and stable angina Flashcards

1
Q

Where is brain natriuretic peptide secreted from?

A

cardiac ventricles in repsonse to increased stress

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2
Q

adverse effects of BB

A

Beta blockers: Bradycardia, hypotension, fatigue, dizziness

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3
Q

adverse effects of ACei

A

Hyperkalaemia, renal impairment, dry cough, lightheadedness, fatigue, GI disturbances, angioedema

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4
Q

adverse effects of spironolactone

A

Hyperkalaemia, renal impairment, gynaecomastia, breast tenderness/hair growth in women, changes in libido

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5
Q

adverse effects of furosemide

A

Hypotension, hypoatraemia/kalaemia,

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6
Q

adverse effects of hydraliazine or nitrates

A

Headache, palpitation, flushing

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6
Q

adverse effects of hydraliazine or nitrates

A

Headache, palpitation, flushing

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7
Q

advserse effects of digoxin( only improves morbitdy worsens mortality)

A

Dizziness, blurred vision, GI disturbances

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8
Q

pharmacolgical mangement in HR

A

ACEi and BB ( ARB instead of ACEi and then hydralize if neiter of them)

furosemide or bumetanide - to imrpove symptoms but not mortality

after that nroamlly class 3 or 4
spironolcatone or eplerenone
hydralazine for afro

ivabradine - imparied ef

digoxin for if combined with AF

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9
Q

in tachycardias after vagal manouveres adenosine is given what happens if the patient is asthmatic

A

give verapamil

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10
Q

delta wave and short PR interval seen in

A

WPW

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11
Q

A 44-year-old female asthmatic patient presents to A&E after complaining of palpitations and shortness of breath. An ECG is performed which shows a supra-ventricular tachycardia of 180 beats per minute. Due to the rapid heart rate, it is not possible to identify the exact cause of the arrhythmia.

What is the most appropriate pharmacological agent to slow down the rate to be able to identify the arrhythmia?

A

verapamil 2.5-5mg

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12
Q

absent arm pulses in young woman

A

Takayasu’s arteritis is a rare form of larger artery vasculitis mainly affecting young women. The classic sign in absent arm pulses. It does not present with acute chest pain

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13
Q

A 23 year old male presents to his general practitioner with a 2 day history of intermittent central, sternal chest pain that feels worse when he wakes up and takes a inspires deeply. He is otherwise fit and well with no relevant past medical history and is a regular gym goer taking no regular medications.

On examination his observations are all within normal range and he has normal heart sounds, a clear chest and a soft and non tender abdomen.

What is the most likely cause of this patient’s chest pain?

A

Costochondritis

Costochondritis is inflammation of the costal cartilage causing pain on respiration. It can be extremely painful and can often be misdiagnosed as a heart attack, however in this young man with no other past medical history or risk factors for cardiac disease it is vanishingly unlikely to be caused by cardiac related issues. The exact aetiology of costocondritis is not well understood however it is thought to be often post-viral. Treatment consists of NSAIDs and adequate hydration with other analgesia as required

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14
Q

pain on respiration think

A

costocondritis - hydrate and pain relief

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15
Q

what CCB are dihydropyridine

A

felodipine, nifidipine and amlodipine - use with BB

diltiazem and verampil - are not - either or to BB at the start in stabel angina

16
Q

investigatons for stable angina

A

This is the correct answer. This patient has presented with 3 typical features of anginal pain and has a negative troponin:

Constriction like pain in chest/neck/arm/jaw
Brought on by physical exertion
Alleviated by rest
NICE guidelines recommend CT coronary angiography as first line for diagnosing stable angina. Second line diagnostic investigations include functional imaging:

Myocardial perfusion SPECT

Stress echo

MRI for regional wall motion abnormalities

Exercise or an inotrope such as dobutamine can be used for a stress echo. In elderly patients exercise testing may not be appropriate, therefore, myocardial perfusion/ MRI scans can be used